ULTRA-SENSITIVE DETECTION OF ENZYMES BY CAPTURE-AND-RELEASE FOLLOWED BY QUANTIFICATION
    1.
    发明申请
    ULTRA-SENSITIVE DETECTION OF ENZYMES BY CAPTURE-AND-RELEASE FOLLOWED BY QUANTIFICATION 审中-公开
    通过定量检测和释放对酶的超敏感检测

    公开(公告)号:US20100075355A1

    公开(公告)日:2010-03-25

    申请号:US12236490

    申请日:2008-09-23

    IPC分类号: C12Q1/34 C12Q1/28

    摘要: The present invention relates to systems and methods for detecting analyte molecules or particles in a fluid sample and in some cases, determining a measure of the concentration of the molecules or particles in the fluid sample. Methods of the present invention may comprise immobilizing a plurality of analyte molecules or particles to form a plurality of complexes, releasing at least a portion of some of the plurality of complexes, determining at least a portion of the plurality of complexes released, and determining a measure of the concentration of the analyte molecules or particles in a fluid sample.

    摘要翻译: 本发明涉及用于检测流体样品中的分析物分子或颗粒的系统和方法,并且在某些情况下,确定流体样品中分子或颗粒的浓度的量度。 本发明的方法可以包括固定多个分析物分子或颗粒以形成多个复合物,释放所述多个复合物中的至少一部分,确定所述多个复合物的至少一部分被释放,并且确定 测量流体样品中分析物分子或颗粒的浓度。

    Ultra-sensitive detection of molecules on single molecule arrays
    2.
    发明授权
    Ultra-sensitive detection of molecules on single molecule arrays 有权
    单分子阵列上分子的超灵敏检测

    公开(公告)号:US08222047B2

    公开(公告)日:2012-07-17

    申请号:US12236486

    申请日:2008-09-23

    IPC分类号: G01N33/543

    摘要: The present invention relates to systems and methods for detecting analyte molecules or particles in a fluid sample and in some cases, determining a measure of the concentration of the molecules or particles in the fluid sample. Methods of the present invention may comprise immobilizing a plurality of analyte molecules or particles to form a plurality of complexes, releasing at least a portion of some of the plurality of complexes, determining at least a portion of the plurality of complexes released, and determining a measure of the concentration of the analyte molecules or particles in a fluid sample.

    摘要翻译: 本发明涉及用于检测流体样品中的分析物分子或颗粒的系统和方法,并且在某些情况下,确定流体样品中分子或颗粒的浓度的量度。 本发明的方法可以包括固定多个分析物分子或颗粒以形成多个复合物,释放所述多个复合物中的至少一部分,确定所述多个复合物的至少一部分被释放,并且确定 测量流体样品中分析物分子或颗粒的浓度。

    Ultra-sensitive detection of molecules on single molecule arrays
    3.
    发明授权
    Ultra-sensitive detection of molecules on single molecule arrays 有权
    单分子阵列上分子的超灵敏检测

    公开(公告)号:US08846415B2

    公开(公告)日:2014-09-30

    申请号:US13527210

    申请日:2012-06-19

    IPC分类号: G01N33/543

    摘要: The present invention relates to systems and methods for detecting analyte molecules or particles in a fluid sample and in some cases, determining a measure of the concentration of the molecules or particles in the fluid sample. Methods of the present invention may comprise immobilizing a plurality of analyte molecules or particles to form a plurality of complexes, releasing at least a portion of some of the plurality of complexes, determining at least a portion of the plurality of complexes released, and determining a measure of the concentration of the analyte molecules or particles in a fluid sample.

    摘要翻译: 本发明涉及用于检测流体样品中的分析物分子或颗粒的系统和方法,并且在某些情况下,确定流体样品中分子或颗粒的浓度的量度。 本发明的方法可以包括固定多个分析物分子或颗粒以形成多个复合物,释放所述多个复合物中的至少一部分,确定所述多个复合物的至少一部分被释放,并且确定 测量流体样品中分析物分子或颗粒的浓度。

    ULTRA-SENSITIVE DETECTION OF MOLECULES ON SINGLE MOLECULE ARRAYS
    4.
    发明申请
    ULTRA-SENSITIVE DETECTION OF MOLECULES ON SINGLE MOLECULE ARRAYS 有权
    对单分子阵列分子的超敏感检测

    公开(公告)号:US20140243223A1

    公开(公告)日:2014-08-28

    申请号:US13527210

    申请日:2012-06-19

    IPC分类号: G01N33/543 C12Q1/68

    摘要: The present invention relates to systems and methods for detecting analyte molecules or particles in a fluid sample and in some cases, determining a measure of the concentration of the molecules or particles in the fluid sample. Methods of the present invention may comprise immobilizing a plurality of analyte molecules or particles to form a plurality of complexes, releasing at least a portion of some of the plurality of complexes, determining at least a portion of the plurality of complexes released, and determining a measure of the concentration of the analyte molecules or particles in a fluid sample.

    摘要翻译: 本发明涉及用于检测流体样品中的分析物分子或颗粒的系统和方法,并且在某些情况下,确定流体样品中分子或颗粒的浓度的量度。 本发明的方法可以包括固定多个分析物分子或颗粒以形成多个复合物,释放所述多个复合物中的至少一部分,确定所述多个复合物的至少一部分被释放,并且确定 测量流体样品中分析物分子或颗粒的浓度。

    ULTRA-SENSITIVE DETECTION OF MOLECULES BY CAPTURE-AND-RELEASE USING REDUCING AGENTS FOLLOWED BY QUANTIFICATION
    5.
    发明申请
    ULTRA-SENSITIVE DETECTION OF MOLECULES BY CAPTURE-AND-RELEASE USING REDUCING AGENTS FOLLOWED BY QUANTIFICATION 审中-公开
    通过使用量化后的还原剂捕获和释放分子的超敏感性检测

    公开(公告)号:US20100075439A1

    公开(公告)日:2010-03-25

    申请号:US12236488

    申请日:2008-09-23

    IPC分类号: G01N33/543

    CPC分类号: G01N33/54306

    摘要: The present invention relates to systems and methods for detecting analyte molecules or particles in a fluid sample and in some cases, determining a measure of the concentration of the molecules or particles in the fluid sample. Methods of the present invention may comprise immobilizing a plurality of analyte molecules or particles to form a plurality of complexes, releasing at least a portion of some of the plurality of complexes, determining at least a portion of the plurality of complexes released, and determining a measure of the concentration of the analyte molecules or particles in a fluid sample.

    摘要翻译: 本发明涉及用于检测流体样品中的分析物分子或颗粒的系统和方法,并且在某些情况下,确定流体样品中分子或颗粒的浓度的量度。 本发明的方法可以包括固定多个分析物分子或颗粒以形成多个复合物,释放所述多个复合物中的至少一部分,确定所述多个复合物的至少一部分被释放,并且确定 测量流体样品中分析物分子或颗粒的浓度。

    ULTRA-SENSITIVE DETECTION OF MOLECULES ON SINGLE MOLECULE ARRAYS
    6.
    发明申请
    ULTRA-SENSITIVE DETECTION OF MOLECULES ON SINGLE MOLECULE ARRAYS 有权
    对单分子阵列分子的超敏感检测

    公开(公告)号:US20100075407A1

    公开(公告)日:2010-03-25

    申请号:US12236486

    申请日:2008-09-23

    IPC分类号: C12M1/34 G01N33/573

    摘要: The present invention relates to systems and methods for detecting analyte molecules or particles in a fluid sample and in some cases, determining a measure of the concentration of the molecules or particles in the fluid sample. Methods of the present invention may comprise immobilizing a plurality of analyte molecules or particles to form a plurality of complexes, releasing at least a portion of some of the plurality of complexes, determining at least a portion of the plurality of complexes released, and determining a measure of the concentration of the analyte molecules or particles in a fluid sample.

    摘要翻译: 本发明涉及用于检测流体样品中的分析物分子或颗粒的系统和方法,并且在某些情况下,确定流体样品中分子或颗粒的浓度的量度。 本发明的方法可以包括固定多个分析物分子或颗粒以形成多个复合物,释放所述多个复合物中的至少一部分,确定所述多个复合物的至少一部分被释放,并且确定 测量流体样品中分析物分子或颗粒的浓度。