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公开(公告)号:US08048439B2
公开(公告)日:2011-11-01
申请号:US11128265
申请日:2005-05-13
申请人: David Dakin Iorwerth Wright , Anthony David Harman , Nikki Robinson , Garry Hodges , Adil Kadar , Geoffrey D. Moggridge , Hugh Van Liew , William John Jenkins
发明人: David Dakin Iorwerth Wright , Anthony David Harman , Nikki Robinson , Garry Hodges , Adil Kadar , Geoffrey D. Moggridge , Hugh Van Liew , William John Jenkins
IPC分类号: A61K9/08
CPC分类号: A61K9/122
摘要: A therapeutic foam for the treatment of, inter alia, varicose veins comprises a sclerosing solution foamed with a physiological gas such as carbon dioxide, oxygen or a mixture thereof. The foam has a nitrogen content of less than 0.8%. It may be generated using a pressurized canister system incorporating a fine mesh of micron dimensions through which the gas and sclerosing liquid are passed to make the foam. Alternatively, the foam may be generated by passing gas and solution between two syringes through a fine mesh. Techniques are described for minimizing the amount of nitrogen in a canister or syringe based product. A technique for generating and delivering foam simultaneously using a syringe based device is also disclosed.
摘要翻译: 用于治疗静脉曲张的治疗性泡沫包括用诸如二氧化碳,氧气或其混合物的生理气体发泡的硬化溶液。 泡沫的氮含量小于0.8%。 它可以使用包含微米尺寸的精细网格的加压罐系统来产生,气体和硬化液通过该微孔尺寸通过以制造泡沫。 或者,泡沫可以通过气体和溶液在两个注射器之间通过细网而产生。 描述了用于最小化基于罐或注射器的产品中氮的量的技术。 还公开了一种使用基于注射器的装置同时产生和递送泡沫的技术。
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公开(公告)号:US07731986B2
公开(公告)日:2010-06-08
申请号:US10522527
申请日:2004-11-17
申请人: David Dakin Iorwerth Wright , Anthony David Harman , Nikki Robinson , Garry Hodges , Adil Kadar , Geoffrey D. Moggridge , Hugh Van Liew
发明人: David Dakin Iorwerth Wright , Anthony David Harman , Nikki Robinson , Garry Hodges , Adil Kadar , Geoffrey D. Moggridge , Hugh Van Liew
IPC分类号: A61K9/08
CPC分类号: B65B3/003 , A61B17/00008 , A61B17/00491 , A61B17/12022 , A61B17/12109 , A61B17/12186 , A61B2017/00495 , A61K9/0019 , A61K9/08 , A61K9/122 , A61K9/124 , A61K31/08 , A61K47/02 , A61K47/10 , A61K47/20 , A61K47/32 , A61M5/178 , A61M5/19 , A61M16/00 , A61M2202/00 , A61M2210/086 , A61M2210/12 , B01F3/04446 , B01F5/0685 , B01F5/0693 , B01F13/0023 , B65B31/00 , Y10S514/945
摘要: A therapeutic foam for the treatment of, inter alia, varicose veins comprises a sclerosing solution foamed with a physiological gas such as carbon dioxide, oxygen or a mixture thereof. The foam has a nitrogen content of less than 0.8%. It may be generated using a pressurised canister system incorporating a fine mesh of micron dimensions through which the gas and sclerosing liquid are passed to make the foam. Alternatively, the foam may be generated by passing gas and solution between two syringes through a fine mesh. Techniques are described for minimising the amount of nitrogen in a canister or syringe based product. A technique for generating and delivering foam simultaneously using a syringe based device is also disclosed.
摘要翻译: 用于治疗静脉曲张的治疗性泡沫包括用诸如二氧化碳,氧气或其混合物的生理气体发泡的硬化溶液。 泡沫的氮含量小于0.8%。 它可以使用包含微米尺寸的精细网格的加压罐系统来产生,气体和硬化液通过该微孔尺寸通过以制造泡沫。 或者,泡沫可以通过气体和溶液在两个注射器之间通过细网而产生。 描述了用于最小化基于罐或注射器的产品中氮的量的技术。 还公开了一种使用基于注射器的装置同时产生和递送泡沫的技术。
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公开(公告)号:US20130059923A1
公开(公告)日:2013-03-07
申请号:US13667296
申请日:2012-11-02
申请人: David Dakin Iorwerth Wright , Anthony David Harman , Nikki Robinson , Garry Hodges, SR. , Adil Kadar , Geoffrey D. Moggridge , Hugh Van Liew
发明人: David Dakin Iorwerth Wright , Anthony David Harman , Nikki Robinson , Garry Hodges, SR. , Adil Kadar , Geoffrey D. Moggridge , Hugh Van Liew
CPC分类号: B65B3/003 , A61B17/00008 , A61B17/00491 , A61B17/12022 , A61B17/12109 , A61B17/12186 , A61B2017/00495 , A61K9/0019 , A61K9/08 , A61K9/122 , A61K9/124 , A61K31/08 , A61K47/02 , A61K47/10 , A61K47/20 , A61K47/32 , A61M5/178 , A61M5/19 , A61M16/00 , A61M2202/00 , A61M2210/086 , A61M2210/12 , B01F3/04446 , B01F5/0685 , B01F5/0693 , B01F13/0023 , B65B31/00 , Y10S514/945
摘要: A therapeutic foam for the treatment of, inter alia, varicose veins comprises a sclerosing solution foamed with a physiological gas such as carbon dioxide, oxygen or a mixture thereof. The foam has a nitrogen content of less than 0.8%. It may be generated using a pressurised canister system incorporating a fine mesh of micron dimensions through which the gas and sclerosing liquid are passed to make the foam. Alternatively, the foam may be generated by passing gas and solution between two syringes through a fine mesh. Techniques are described for minimising the amount of nitrogen in a canister or syringe based product. A technique for generating and delivering foam simultaneously using a syringe based device is also disclosed.
摘要翻译: 用于治疗静脉曲张的治疗性泡沫包括用诸如二氧化碳,氧气或其混合物的生理气体发泡的硬化溶液。 泡沫的氮含量小于0.8%。 它可以使用包含微米尺寸的精细网格的加压罐系统来产生,气体和硬化液通过该微孔尺寸通过以制造泡沫。 或者,泡沫可以通过气体和溶液在两个注射器之间通过细网而产生。 描述了用于最小化基于罐或注射器的产品中氮的量的技术。 还公开了一种使用基于注射器的装置同时产生和递送泡沫的技术。
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公开(公告)号:US07763269B2
公开(公告)日:2010-07-27
申请号:US10522528
申请日:2004-11-17
申请人: David Dakin Iorwerth Wright , Anthony David Harman , Nikki Robinson , Garry Hodges , Adil Kadar , Geoffrey D. Moggridge , Hugh Van Liew
发明人: David Dakin Iorwerth Wright , Anthony David Harman , Nikki Robinson , Garry Hodges , Adil Kadar , Geoffrey D. Moggridge , Hugh Van Liew
CPC分类号: B65B3/003 , A61B17/00008 , A61B17/00491 , A61B17/12022 , A61B17/12109 , A61B17/12186 , A61B2017/00495 , A61K9/0019 , A61K9/08 , A61K9/122 , A61K9/124 , A61K31/08 , A61K47/02 , A61K47/10 , A61K47/20 , A61K47/32 , A61M5/178 , A61M5/19 , A61M16/00 , A61M2202/00 , A61M2210/086 , A61M2210/12 , B01F3/04446 , B01F5/0685 , B01F5/0693 , B01F13/0023 , B65B31/00 , Y10S514/945
摘要: A therapeutic foam for the treatment of, inter alia, varicose veins comprises a sclerosing solution foamed with a physiological gas such as carbon dioxide, oxygen or a mixture thereof. The foam has a nitrogen content of less than 0.8%. It may be generated using a pressurised canister system incorporating a fine mesh of micron dimensions through which the gas and sclerosing liquid are passed to make the foam. Alternatively, the foam may be generated by passing gas and solution between two syringes through a fine mesh. Techniques are described for minimising the amount of nitrogen in a canister or syringe based product. A technique for generating and delivering foam simultaneously using a syringe based device is also disclosed.
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公开(公告)号:US08323677B2
公开(公告)日:2012-12-04
申请号:US12765980
申请日:2010-04-23
申请人: David Dakin Iorwerth Wright , Anthony David Harman , Nikki Robinson , Garry Hodges , Adil Kadar , Geoffrey D. Moggridge , Hugh Van Liew
发明人: David Dakin Iorwerth Wright , Anthony David Harman , Nikki Robinson , Garry Hodges , Adil Kadar , Geoffrey D. Moggridge , Hugh Van Liew
IPC分类号: A61K9/08
CPC分类号: B65B3/003 , A61B17/00008 , A61B17/00491 , A61B17/12022 , A61B17/12109 , A61B17/12186 , A61B2017/00495 , A61K9/0019 , A61K9/08 , A61K9/122 , A61K9/124 , A61K31/08 , A61K47/02 , A61K47/10 , A61K47/20 , A61K47/32 , A61M5/178 , A61M5/19 , A61M16/00 , A61M2202/00 , A61M2210/086 , A61M2210/12 , B01F3/04446 , B01F5/0685 , B01F5/0693 , B01F13/0023 , B65B31/00 , Y10S514/945
摘要: A therapeutic foam for the treatment of, inter alia, varicose veins comprises a sclerosing solution foamed with a physiological gas such as carbon dioxide, oxygen or a mixture thereof. The foam has a nitrogen content of less than 0.8%. It may be generated using a pressurized canister system incorporating a fine mesh of micron dimensions through which the gas and sclerosing liquid are passed to make the foam. Alternatively, the foam may be generated by passing gas and solution between two syringes through a fine mesh. Techniques are described for minimizing the amount of nitrogen in a canister or syringe based product. A technique for generating and delivering foam simultaneously using a syringe based device is also disclosed.
摘要翻译: 用于治疗静脉曲张的治疗性泡沫包括用诸如二氧化碳,氧气或其混合物的生理气体发泡的硬化溶液。 泡沫的氮含量小于0.8%。 它可以使用包含微米尺寸的精细网格的加压罐系统来产生,气体和硬化液通过该微孔尺寸通过以制造泡沫。 或者,泡沫可以通过气体和溶液在两个注射器之间通过细网而产生。 描述了用于最小化基于罐或注射器的产品中氮的量的技术。 还公开了一种使用基于注射器的装置同时产生和递送泡沫的技术。
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公开(公告)号:US20100203171A1
公开(公告)日:2010-08-12
申请号:US12765980
申请日:2010-04-23
申请人: David Dakin Iorwerth WRIGHT , Anthony David Harman , Nikki Robinson , Garry Hodges , Adil Kadar , Geoffrey D. Moggridge , Hugh Van Liew
发明人: David Dakin Iorwerth WRIGHT , Anthony David Harman , Nikki Robinson , Garry Hodges , Adil Kadar , Geoffrey D. Moggridge , Hugh Van Liew
CPC分类号: B65B3/003 , A61B17/00008 , A61B17/00491 , A61B17/12022 , A61B17/12109 , A61B17/12186 , A61B2017/00495 , A61K9/0019 , A61K9/08 , A61K9/122 , A61K9/124 , A61K31/08 , A61K47/02 , A61K47/10 , A61K47/20 , A61K47/32 , A61M5/178 , A61M5/19 , A61M16/00 , A61M2202/00 , A61M2210/086 , A61M2210/12 , B01F3/04446 , B01F5/0685 , B01F5/0693 , B01F13/0023 , B65B31/00 , Y10S514/945
摘要: A therapeutic foam for the treatment of, inter alia, varicose veins comprises a sclerosing solution foamed with a physiological gas such as carbon dioxide, oxygen or a mixture thereof. The foam has a nitrogen content of less than 0.8%. It may be generated using a pressurised canister system incorporating a fine mesh of micron dimensions through which the gas and sclerosing liquid are passed to make the foam. Alternatively, the foam may be generated by passing gas and solution between two syringes through a fine mesh. Techniques are described for minimising the amount of nitrogen in a canister or syringe based product. A technique for generating and delivering foam simultaneously using a syringe based device is also disclosed.
摘要翻译: 用于治疗静脉曲张的治疗性泡沫包括用诸如二氧化碳,氧气或其混合物的生理气体发泡的硬化溶液。 泡沫的氮含量小于0.8%。 它可以使用包含微米尺寸的精细网格的加压罐系统来产生,气体和硬化液通过该微孔尺寸通过以制造泡沫。 或者,泡沫可以通过气体和溶液在两个注射器之间通过细网而产生。 描述了用于最小化基于罐或注射器的产品中氮的量的技术。 还公开了一种使用基于注射器的装置同时产生和递送泡沫的技术。
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公开(公告)号:US20080274060A1
公开(公告)日:2008-11-06
申请号:US11914190
申请日:2006-05-12
申请人: David Dakin Iorwerth Wright , Anthony David Harman , Nikki Robinson , Garry Hodges , Adil Kadar , Hugh Van Liew , Geoffrey D. Moggridge , William John Jenkins
发明人: David Dakin Iorwerth Wright , Anthony David Harman , Nikki Robinson , Garry Hodges , Adil Kadar , Hugh Van Liew , Geoffrey D. Moggridge , William John Jenkins
CPC分类号: A61K9/0019 , A61K9/122 , A61K9/124 , A61K31/77
摘要: A foam is described for injection treatment of varicose veins. The foam comprises a sclerosant liquid, e.g. polidocanol solution, and a gas. The gas comprises xenon, optionally together with at least one other physiologically acceptable gas which is readily absorbed in the body or blood of a patient. The gas comprises only a minimal amount of gaseous nitrogen, between 0.0001% and 0.8%.
摘要翻译: 描述了用于静脉曲张的注射治疗的泡沫。 泡沫包括硬化液体,例如, 波多契醇溶液和气体。 气体包括氙,任选地与至少一种容易被吸收在患者体内或血液中的生理上可接受的气体组合。 气体仅包含最小量的气态氮,介于0.0001%和0.8%之间。
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公开(公告)号:US08235935B2
公开(公告)日:2012-08-07
申请号:US12518479
申请日:2007-12-21
申请人: David Dakin Iorwerth Wright , Anthony David Harman , Garry Hodges , David John Targell , Mark Simpson Yeoman , Jeremy Francis Donnan
发明人: David Dakin Iorwerth Wright , Anthony David Harman , Garry Hodges , David John Targell , Mark Simpson Yeoman , Jeremy Francis Donnan
CPC分类号: B29C44/3442 , A61K9/122 , B01F3/04446 , B01F5/102
摘要: A device and a method for generating therapeutic foam from a sclerosing solution such as polidocanol and a gas which is absorbable or dissolvable in the body comprises a disposable cassette including a liquid container and a flexible chamber containing gas, chamber being formed as a loop. Located in the loop chamber is a foam generating mesh. In use, liquid is introduced into the chamber and then the cassette is inserted into a pumping machine where it is engaged by a peristaltic pump which circulates the contents of the loop chamber through the mesh, thus creating foam. When a steady state is reached, foam may be withdrawn using a syringe via either a port or septum.
摘要翻译: 一种用于从诸如波多契醇和可吸收或可溶于体内的气体产生治疗性泡沫的装置和方法包括:一个包含液体容器的一次性盒和一个容纳气体的柔性室,形成为环。 位于环形室中的是泡沫生成网。 在使用中,将液体引入室中,然后将盒子插入泵送机器中,其中蠕动泵将蠕动泵接合,循环泵的内容物通过网孔循环,从而产生泡沫。 当达到稳定状态时,可以使用注射器通过端口或隔膜抽出泡沫。
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公开(公告)号:US20120273977A1
公开(公告)日:2012-11-01
申请号:US13544984
申请日:2012-07-09
申请人: David Dakin Iorwerth Wright , Anthony David Harman , Garry Hodges , David John Targell , Mark Simpson Yeoman , Jeremy Francis Donnan
发明人: David Dakin Iorwerth Wright , Anthony David Harman , Garry Hodges , David John Targell , Mark Simpson Yeoman , Jeremy Francis Donnan
IPC分类号: B01F3/04
CPC分类号: B29C44/3442 , A61K9/122 , B01F3/04446 , B01F5/102
摘要: A device and a method for generating therapeutic foam from a sclerosing solution such as polidocanol and a gas which is absorbable or dissolvable in the body comprises a disposable cassette including a liquid container and a flexible chamber containing gas, chamber being formed as a loop. Located in the loop chamber is a foam generating mesh. In use, liquid is introduced into the chamber and then the cassette is inserted into a pumping machine where it is engaged by a peristaltic pump which circulates the contents of the loop chamber through the mesh, thus creating foam. When a steady state is reached, foam may be withdrawn using a syringe via either a port or septum.
摘要翻译: 一种用于从诸如波多契醇和可吸收或可溶于体内的气体产生治疗性泡沫的装置和方法包括:一个包含液体容器的一次性盒和一个容纳气体的柔性室,形成为环。 位于环形室中的是泡沫生成网。 在使用中,将液体引入室中,然后将盒子插入泵送机器中,其中蠕动泵将蠕动泵接合,循环泵的内容物通过网孔循环,从而产生泡沫。 当达到稳定状态时,可以使用注射器通过端口或隔膜抽出泡沫。
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公开(公告)号:US20100099778A1
公开(公告)日:2010-04-22
申请号:US12518479
申请日:2007-12-21
申请人: David Dakin Iorwerth Wright , Anthony David Harman , Garry Hodges , David John Targell , Mark Simpson Yeoman , Jeremy Francis Donnan
发明人: David Dakin Iorwerth Wright , Anthony David Harman , Garry Hodges , David John Targell , Mark Simpson Yeoman , Jeremy Francis Donnan
CPC分类号: B29C44/3442 , A61K9/122 , B01F3/04446 , B01F5/102
摘要: A device and a method for generating therapeutic foam from a sclerosing solution such as polidocanol and a gas which is absorbable or dissolvable in the body comprises a disposable cassette including a liquid container and a flexible chamber containing gas, chamber being formed as a loop. Located in the loop chamber is a foam generating mesh. In use, liquid is introduced into the chamber and then the cassette is inserted into a pumping machine where it is engaged by a peristaltic pump which circulates the contents of the loop chamber through the mesh, thus creating foam. When a steady state is reached, foam may be withdrawn using a syringe via either a port or septum.
摘要翻译: 一种用于从诸如波多契醇和可吸收或可溶于体内的气体产生治疗性泡沫的装置和方法包括:一个包含液体容器的一次性盒和一个容纳气体的柔性室,形成为环。 位于环形室中的是泡沫生成网。 在使用中,将液体引入室中,然后将盒子插入泵送机器中,其中蠕动泵将蠕动泵接合,循环泵的内容物通过网孔循环,从而产生泡沫。 当达到稳定状态时,可以使用注射器通过端口或隔膜抽出泡沫。
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