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公开(公告)号：US08886308B2
公开(公告)日：2014-11-11
申请号：US13401965
申请日：2012-02-22
CPC分类号： A61N1/3987 , A61N1/3682 , A61N1/3937 , A61N1/3962
摘要： An atrial event and a ventricular event can be received, and an atrioventricular (AV) delay can be provided using information about the atrial and ventricular events. The AV delay can be increased after a first condition is satisfied to allow a heart to regain intrinsic control of ventricular activation, and changed after a second condition is satisfied to allow the heart to remain in intrinsic control of ventricular activation.
摘要翻译： 可以接收心房事件和心室事件，并且可以使用关于心房和心室事件的信息来提供房室（AV）延迟。 在满足第一条件以允许心脏恢复心室激活的内在控制之后，AV延迟可以增加，并且在第二个条件被满足以允许心脏保持在心室激活的内在控制之后改变。
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公开(公告)号：US20120150254A1
公开(公告)日：2012-06-14
申请号：US13401965
申请日：2012-02-22
IPC分类号： A61N1/365
CPC分类号： A61N1/3987 , A61N1/3682 , A61N1/3937 , A61N1/3962
摘要： An atrial event and a ventricular event can be received, and an atrioventricular (AV) delay can be provided using information about the atrial and ventricular events. The AV delay can be increased after a first condition is satisfied to allow a heart to regain intrinsic control of ventricular activation, and changed after a second condition is satisfied to allow the heart to remain in intrinsic control of ventricular activation.
摘要翻译： 可以接收心房事件和心室事件，并且可以使用关于心房和心室事件的信息来提供房室（AV）延迟。 在满足第一条件以允许心脏恢复心室激活的内在控制之后，AV延迟可以增加，并且在第二个条件被满足以允许心脏保持在心室激活的内在控制之后改变。
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公开(公告)号：US06427084B2
公开(公告)日：2002-07-30
申请号：US09514813
申请日：2000-02-28
IPC分类号： A61N1362
CPC分类号： A61N1/368 , A61N1/3622 , A61N1/3684
摘要： A hybrid cardiac pacemaker in which the operation of the device is controlled by hardware-based controller as supervised by a microprocessor-based controller. The hardware-based controller comprises a plurality of timers that expire when they reach timer limit values stored in registers updatable by the microprocessor, and a combinational logic array for causing the device to generate pace outputs in accordance with timer expirations and sense signals. The combinational logic array may operate the pacemaker in a number of programmed modes in accordance with a mode value stored in a mode control register by the microprocessor.
摘要翻译： 一种混合心脏起搏器，其中由基于微处理器的控制器监控的由基于硬件的控制器控制该设备的操作。 基于硬件的控制器包括多个定时器，当它们达到存储在可由微处理器更新的寄存器中的定时器限制值时，该定时器到期，以及组合逻辑阵列，用于使该设备根据定时器期满和感测信号产生步进输出。 组合逻辑阵列可以根据由微处理器存储在模式控制寄存器中的模式值，以多种编程模式操作起搏器。
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公开(公告)号：US20120197323A1
公开(公告)日：2012-08-02
申请号：US13353515
申请日：2012-01-19
申请人： Efdal Elferri , Randall L. McPherson , Donald L. Hopper , Gary T. Seim , James O. Gilkerson , Dan Li , David L. Perschbacher
发明人： Efdal Elferri , Randall L. McPherson , Donald L. Hopper , Gary T. Seim , James O. Gilkerson , Dan Li , David L. Perschbacher
IPC分类号： A61N1/39 , A61N1/365 , A61B5/0205
CPC分类号： A61N1/36585 , A61B5/0464 , A61B5/0538 , A61B5/0809 , A61B5/091 , A61B5/686 , A61N1/3962
摘要： An implantable or ambulatory medical device can include a cardiac signal sensing circuit configured to provide a sensed cardiac depolarization signal of a heart of a subject, a respiration sensing circuit configured to provide a signal representative of respiration of the subject, and a control circuit communicatively coupled to the cardiac signal sensing circuit and the respiration circuit. The control circuit includes a tachyarrhythmia detection circuit configured to determine heart rate using the depolarization signal, determine a respiration parameter of the subject using the respiration signal, calculate a ratio using the determined heart rate and the determined respiration parameter, generate an indication of tachyarrhythmia when the calculated ratio satisfies a specified detection ratio threshold value, and provide the indication of tachyarrhythmia to a user or process.
摘要翻译： 植入式或动态医疗装置可以包括心脏信号感测电路，该心脏信号感测电路被配置为提供受检者的心脏的感测的心脏去极化信号，被配置为提供代表对象呼吸的信号的呼吸感测电路，以及通信耦合的控制电路 到心脏信号感测电路和呼吸电路。 控制电路包括快速性心律失常检测电路，其被配置为使用去极化信号来确定心率，使用呼吸信号确定受试者的呼吸参数，使用所确定的心率和确定的呼吸参数来计算比率，产生快速性心律失常的指示， 所计算的比率满足规定的检测率阈值，并向用户或过程提供快速性心律失常的指示。
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公开(公告)号：US20090149907A1
公开(公告)日：2009-06-11
申请号：US12330869
申请日：2008-12-09
IPC分类号： A61N1/368
CPC分类号： A61N1/3987 , A61N1/3682 , A61N1/3937 , A61N1/3962
摘要： An atrial event and a ventricular event can be received, and an atrioventricular (AV) delay can be provided using information about the atrial and ventricular events. The AV delay can be increased after a first condition is satisfied to allow a heart to regain intrinsic control of ventricular activation, and changed after a second condition is satisfied to allow the heart to remain in intrinsic control of ventricular activation.
摘要翻译： 可以接收心房事件和心室事件，并且可以使用关于心房和心室事件的信息来提供房室（AV）延迟。 在满足第一条件以允许心脏恢复心室激活的内在控制之后，AV延迟可以增加，并且在第二个条件被满足以允许心脏保持在心室激活的内在控制之后改变。
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公开(公告)号：US08639324B2
公开(公告)日：2014-01-28
申请号：US13353515
申请日：2012-01-19
申请人： Efdal Elferri , Randall L. McPherson , Donald L. Hopper , Gary T. Seim , James O. Gilkerson , Dan Li , David L. Perschbacher
发明人： Efdal Elferri , Randall L. McPherson , Donald L. Hopper , Gary T. Seim , James O. Gilkerson , Dan Li , David L. Perschbacher
IPC分类号： A61B5/0205 , A61N1/365 , A61N1/39
CPC分类号： A61N1/36585 , A61B5/0464 , A61B5/0538 , A61B5/0809 , A61B5/091 , A61B5/686 , A61N1/3962
摘要： An implantable or ambulatory medical device can include a cardiac signal sensing circuit configured to provide a sensed cardiac depolarization signal of a heart of a subject, a respiration sensing circuit configured to provide a signal representative of respiration of the subject, and a control circuit communicatively coupled to the cardiac signal sensing circuit and the respiration circuit. The control circuit includes a tachyarrhythmia detection circuit configured to determine heart rate using the depolarization signal, determine a respiration parameter of the subject using the respiration signal, calculate a ratio using the determined heart rate and the determined respiration parameter, generate an indication of tachyarrhythmia when the calculated ratio satisfies a specified detection ratio threshold value, and provide the indication of tachyarrhythmia to a user or process.
摘要翻译： 植入式或动态医疗装置可以包括心脏信号感测电路，该心脏信号感测电路被配置为提供受检者的心脏的感测的心脏去极化信号，被配置为提供代表对象呼吸的信号的呼吸感测电路，以及通信耦合的控制电路 到心脏信号感测电路和呼吸电路。 控制电路包括快速性心律失常检测电路，其被配置为使用去极化信号来确定心率，使用呼吸信号确定受试者的呼吸参数，使用所确定的心率和确定的呼吸参数来计算比率，产生快速性心律失常的指示， 所计算的比率满足规定的检测率阈值，并向用户或过程提供快速性心律失常的指示。
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公开(公告)号：US08126551B2
公开(公告)日：2012-02-28
申请号：US12330869
申请日：2008-12-09
IPC分类号： A61N1/00
CPC分类号： A61N1/3987 , A61N1/3682 , A61N1/3937 , A61N1/3962
摘要： An atrial event and a ventricular event can be received, and an atrioventricular (AV) delay can be provided using information about the atrial and ventricular events. The AV delay can be increased after a first condition is satisfied to allow a heart to regain intrinsic control of ventricular activation, and changed after a second condition is satisfied to allow the heart to remain in intrinsic control of ventricular activation.
摘要翻译： 可以接收心房事件和心室事件，并且可以使用关于心房和心室事件的信息来提供房室（AV）延迟。 在满足第一条件以允许心脏恢复心室激活的内在控制之后，AV延迟可以增加，并且在第二个条件被满足以允许心脏保持在心室激活的内在控制之后改变。
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公开(公告)号：US06920355B2
公开(公告)日：2005-07-19
申请号：US10150297
申请日：2002-05-17
CPC分类号： A61N1/368 , A61N1/3622 , A61N1/3684
摘要： A hybrid cardiac pacemaker in which the operation of the device is controlled by hardware-based controller as supervised by a microprocessor-based controller. The hardware-based controller comprises a plurality of timers that expire when they reach timer limit values stored in registers updatable by the microprocessor, and a combinational logic array for causing the device to generate pace outputs in accordance with timer expirations and sense signals. The combinational logic array may operate the pacemaker in a number of programmed modes in accordance with a mode value stored in a mode control register by the microprocessor.
摘要翻译： 一种混合心脏起搏器，其中由基于微处理器的控制器监控的由基于硬件的控制器控制该设备的操作。 基于硬件的控制器包括多个定时器，当它们达到存储在可由微处理器更新的寄存器中的定时器限制值时，该定时器到期，以及组合逻辑阵列，用于使该设备根据定时器期满和感测信号产生步进输出。 组合逻辑阵列可以根据由微处理器存储在模式控制寄存器中的模式值，以多种编程模式操作起搏器。
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公开(公告)号：US20100305643A1
公开(公告)日：2010-12-02
申请号：US12784151
申请日：2010-05-20
申请人： Paul F. Emerson , Gary T. Seim , Michael A. Querimit , Donald L. Hopper , Stephen R. Pitzl , Daniel O'Brien
发明人： Paul F. Emerson , Gary T. Seim , Michael A. Querimit , Donald L. Hopper , Stephen R. Pitzl , Daniel O'Brien
IPC分类号： A61N1/365
CPC分类号： A61N1/36521 , A61N1/362 , A61N1/365 , A61N1/37
摘要： A cardiac rhythm management (CRM) device can extract ventilation information from thoracic impedance or other information, and adjust a delivery rate of the CRM therapy. A tidal volume of a patient is measured and used to adjust a ventilation rate response factor. The measured tidal volume can optionally be adjusted using a ventilation rate dependent adjustment factor. The ventilation rate response factor can also be adjusted using a maximum voluntary ventilation (MVV), an age predicted maximum heart rate, a resting heart rate, and a resting ventilation determined for the patient. In various examples, a global ventilation sensor rate response factor (for a population) can be programmed into the CRM device, and automatically tailored to be appropriate for a particular patient.
摘要翻译： 心脏节律管理（CRM）设备可以从胸部阻抗或其他信息中提取通气信息，并调整CRM治疗的输送速率。 测量患者的潮气量并用于调节通气率反应因子。 测量的潮气量可以任选地使用通风率依赖调节因子进行调整。 通气率反应因子也可以使用最大自主通气（MVV），年龄预测最大心率，静息心率和为患者确定的休息通气进行调整。 在各种示例中，可将全球通气传感器速率响应因子（对于群体）编程到CRM设备中，并且被自动调整为适合于特定患者。
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10.发明申请Methods and Systems for Mitigating the Occurrence of Arrhythmia During Atrial Pacing 有权心房起搏减轻心律失常发生的方法和系统公开(公告)号：US20100286743A1
公开(公告)日：2010-11-11
申请号：US12772725
申请日：2010-05-03
申请人： Eric K. Enrooth , Yanting Dong , Kenneth N. Hayes , Gary T. Seim , Kevin John Stalsberg , Aaron McCabe
发明人： Eric K. Enrooth , Yanting Dong , Kenneth N. Hayes , Gary T. Seim , Kevin John Stalsberg , Aaron McCabe
IPC分类号： A61N1/37
CPC分类号： A61N1/3712 , A61N1/3622 , A61N1/3714
摘要： Noncaptured atrial paces can result in long-short cardiac cycles which are proarrhythmic for ventricular tachyarrhythmia. Approaches are described which are directed to avoiding proarrhythmic long-short cycles. For cardiac cycles in which the atrial pace captures the atrium, a first post ventricular refractory period (PVARP) and a first A-A interval are used. For cardiac cycles in which the atrial pace does not capture the atrium, both an extended PVARP and an extended A-A interval are used. The A-A interval following a noncaptured atrial pace is extended from an atrial depolarization sensed during the extended PVARP.
摘要翻译： 非心房颤动可导致心律失常的心律失常的长时间心脏周期。 描述了旨在避免心律失常长时间短周期的方法。 对于心房搏动捕获心房的心脏周期，使用第一个心室后不应期（PVARP）和第一个A-A间隔。 对于其中心房速度不捕获心房的心脏周期，使用延长的PVARP和延长的A-A间隔。 在非扩张性PVARP期间感觉到的心房去极化之后，A-A间隔未被捕获。
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