Compositions and methods for enhancing or treating female sexual response
    2.
    发明授权
    Compositions and methods for enhancing or treating female sexual response 有权
    用于增强或治疗女性性反应的组合物和方法

    公开(公告)号:US07875299B2

    公开(公告)日:2011-01-25

    申请号:US10834162

    申请日:2004-04-29

    IPC分类号: A01N65/00

    摘要: The present invention relates to compositions, articles of manufacture, methods of preparation thereof, methods of use thereof, etc., for enhancement of sexual pleasure, conditions, disorders, and diseases related to reproductive physiology and systems, especially of mammalian females. For instance, the present invention relates to all aspects of modulating the female sexual response, including female sexual dysfunction, such as female sexual arousal disorders (FSAD), orgasmic disorders, and sexual pain disorders, and enhancing female sexual pleasure and satisfaction of the female sexual experience. Accordingly, the present invention relates to compositions comprising botanical extracts, active agents, etc., which are useful to treat or affect any of the aforementioned conditions. For example, the present invention relates to a composition, preferably for topical or local use, which comprises one or more of the following ingredients, including, but not limited to, borage seed oil, Angelica pubescens root and other angelica species, Coleus forskohlii extract, vinpocetine, ferulic acid, magnesium, ascorbyl palmitate, capric/caprylic triglyceride, silica, and equivalents thereof.

    摘要翻译: 本发明涉及组合物,制品,其制备方法,使用方法等,用于增强性快感,病症,病症以及与生殖生理学和系统特别是哺乳动物雌性有关的疾病。 例如,本发明涉及调节女性性反应的所有方面,包括女性性功能障碍,例如女性性唤起障碍(FSAD),性高潮障碍和性疼痛障碍,以及增强女性性快感和对女性的满意度 性经验。 因此,本发明涉及可用于治疗或影响任何上述病症的植物提取物,活性剂等的组合物。 例如,本发明涉及一种组合物,优选用于局部或局部使用,其包含以下成分中的一种或多种,​​包括但不限于琉璃苣种子油,当归根和当归等,提取物Coleus forskohlii提取物 ,长春西汀,阿魏酸,镁,抗坏血酸棕榈酸酯,癸酸/辛酸甘油三酯,二氧化硅及其等同物。

    Compositions and methods for enhancing or treating female sexual response
    3.
    发明授权
    Compositions and methods for enhancing or treating female sexual response 有权
    用于增强或治疗女性性反应的组合物和方法

    公开(公告)号:US06737084B2

    公开(公告)日:2004-05-18

    申请号:US09891526

    申请日:2001-06-27

    IPC分类号: A61K3578

    摘要: The present invention relates to compositions and methods for enhancement of sexual pleasure and disorders related to sexual pleasure especially in mammalian females. The present invention relates to all aspects of modulating the female sexual response, including female sexual dysfunction such as female sexual arousal disorders (FSAD), orgasmic disorders, sexual pain disorders and enhancing female sexual pleasure and satisfaction. The present invention relates to compositions comprising botanical extracts and active agents which are useful to treat or affect any of the aforementioned conditions. The present invention relates to a composition, preferably for topical or local use, which comprises one or more of the following ingredients; including, but not limited to, borage seed oil, Angelica pubescens root and other Angelica species, Coleus forskohlii extract, vinpocetine, ferulic acid, magnesium, ascorbyl palmitate, capric triglyceride, caprylic triglyceride, silica and equivalents thereof.

    摘要翻译: 本发明涉及用于增强与快乐有关的性快乐和障碍的组合物和方法,特别是在哺乳动物雌性中。 本发明涉及调节女性性反应的所有方面,包括女性性功能障碍如女性性唤起障碍(FSAD),性高潮障碍,性疼痛障碍和增强女性性快感和满意度。 本发明涉及包含可用于治疗或影响任何上述病症的植物提取物和活性剂的组合物。 本发明涉及一种组合物,优选用于局部或局部使用,其包含一种或多种以下成分; 包括但不限于琉璃苣种子油,当归等当归,柯氏梭菌提取物,长春西汀,阿魏酸,镁,抗坏血酸棕榈酸酯,癸酸甘油三酯,辛酸甘油三酯,二氧化硅及其等同物。

    Folding apparatus with multiple speed folding jaw cylinder
    4.
    发明授权
    Folding apparatus with multiple speed folding jaw cylinder 失效
    具有多速折叠颚圆柱的折叠装置

    公开(公告)号:US5522586A

    公开(公告)日:1996-06-04

    申请号:US301822

    申请日:1994-09-07

    CPC分类号: B65H45/168

    摘要: Continuous web-fed rotary tuck and jaw type folding apparatus, typically for high speed periodical, catalogue or newspaper production, is speedily and readily convertible to produce differently page sized and differently folded signatures. Said apparatus has severing means for cutting the web into a stream of discrete signatures; a first rotary cylinder having pin or other transport means and first tuck means carrying those signatures on its periphery, a second rotary cylinder having first or main jaw means coacting with said first tuck means whereby a central cross fold is created in each signature as it is taken off the first cylinder periphery onto the second cylinder periphery to provide a tabloid format signature; and one or more third cylinders each provided with independently operable sets of gripper and second jaw means, the gripper means operating with the third cylinder running in timed relationship so that they take off said tabloid folded signatures for onward transmission, and the second jaw means operating with the third cylinder running in timed relationship to second tucking means of the second cylinder so as to form a further central cross fold in each tabloid signature as it is taken off the second cylinder periphery to provide a double-parallel folded signature.

    摘要翻译: 通常用于高速定期,目录或报纸生产的连续卷筒纸式旋转卷取和颚式折叠装置可快速且容易地转换成不同尺寸和不同的折叠签名。 所述装置具有切割装置,用于将网状物切割成离散的签名流; 具有销或其他输送装置的第一旋转圆筒和在其周边上承载这些标记的第一回转装置,具有与所述第一收集装置共同作用的第一或主颚构件的第二旋转圆筒,因此在每个特征中产生中心十字折叠,因为它是 从第一圆筒周边排出到第二圆筒周边以提供小报格式签名; 以及一个或多个第三气缸,每个气缸均设置有可独立操作的夹持器和第二钳口装置组,所述夹持装置以与时间关系运行的第三气缸一起工作,使得它们脱离所述小报折叠签名用于向前传送,并且第二钳口装置操作 其中第三圆柱体以与第二圆柱体的第二折叠装置成时关系的方式运行,以便当它从第二圆筒周边取出以提供双平行折叠签名时,在每个小报签名中形成另外的中心十字折叠。

    Shared inverter outputs delay system
    5.
    发明授权
    Shared inverter outputs delay system 失效
    共享逆变器输出延时系统

    公开(公告)号:US5049767A

    公开(公告)日:1991-09-17

    申请号:US345926

    申请日:1989-05-01

    IPC分类号: H03K5/00 H03K5/13

    CPC分类号: H03K5/133 H03K2005/00163

    摘要: A delay timer formed by a sequence of inverters alternating in type, some with single and some with multiple outputs each having an output connected to the input of the next. An output from each of the multiple output inverters is connected to the timer output.

    摘要翻译: 由一系列逆变器形成的延迟定时器,其类型交替,一些具有单个,一些具有多个输出,每个具有连接到下一个的输入的输出。 来自多个输出反相器的每一个的输出连接到定时器输出。

    Continuous tone decoder/encoder
    6.
    发明授权
    Continuous tone decoder/encoder 失效
    连续音解码器/编码器

    公开(公告)号:US4484354A

    公开(公告)日:1984-11-20

    申请号:US197408

    申请日:1980-10-16

    IPC分类号: H04W88/02 H04B1/48 H04Q1/45

    CPC分类号: H04W88/027

    摘要: An improved encoder/decoder circuit which utilizes a phase locked loop frequency synthesizer configuration to permit both encoder and decoder operation. In addition, a sampling filter detector is employed to permit monolithic integration of the circuit and minimize sensitivity to vibration. The sampling filter detector has digitally controlled bandwidth which permits rapid response to reverse burst turn-off. In addition, the circuit includes a pulse adder to implement an energy limited reverse burst turn-off mode.

    摘要翻译: 一种改进的编码器/解码器电路,其利用锁相环频率合成器配置来允许编码器和解码器操作。 此外,使用采样滤波器检测器来允许电路的单片集成并且使对振动的灵敏度最小化。 采样滤波器检测器具有数字控制的带宽,允许快速响应反向脉冲串关断。 此外,该电路包括一个脉冲加法器,以实现能量限制反向脉冲串关断模式。

    Mammalian cell surface DNA receptor-encoding nucleic acid
    7.
    发明授权
    Mammalian cell surface DNA receptor-encoding nucleic acid 失效
    哺乳动物细胞表面DNA受体编码核酸

    公开(公告)号:US06602707B2

    公开(公告)日:2003-08-05

    申请号:US09921099

    申请日:2001-08-01

    IPC分类号: C07H2104

    摘要: The present invention relates to novel mammalian DNA-R proteins and genes that encode such proteins. The invention is directed toward the isolation and characterization of mammalian DNA-R proteins. The invention specifically provides isolated complementary DNA copies of mRNA corresponding to rat and human homologues of a mammalian DNA-R gene. Also provided are recombinant expression constructs capable of expressing the mammalian DNA-R genes of the invention in cultures of transformed prokaryotic and eukaryotic cells, as well as such cultures of transformed cells that synthesize the mammalian catecholamine receptor proteins encoded therein. The invention also provides methods for screening compounds in vitro that are capable of binding to the mammalian DNA-R proteins of the invention, and further characterizing the binding properties of such compounds in comparison with known DNA-R agonists and antagonists. Improved methods of pharmacological screening are provided thereby.

    摘要翻译: 本发明涉及新型哺乳动物DNA-R蛋白和编码这种蛋白质的基因。 本发明涉及哺乳动物DNA-R蛋白的分离和表征。 本发明特别提供了与哺乳动物DNA-R基因的大鼠和人类同系物相对应的mRNA的分离的互补DNA拷贝。 还提供了能够在转化的原核和真核细胞的培养物中表达本发明的哺乳动物DNA-R基因以及合成其中编码的哺乳动物儿茶酚胺受体蛋白质的转化细胞的这种培养物的重组表达构建体。 本发明还提供了在体外筛选能够结合本发明的哺乳动物DNA-R蛋白的方法,并且与已知的DNA-R激动剂和拮抗剂相比进一步表征了这些化合物的结合特性。 从而提供改进的药理学筛选方法。

    Current replication circuit and method for use in exhaust gas oxygen
monitoring
    8.
    发明授权
    Current replication circuit and method for use in exhaust gas oxygen monitoring 失效
    目前复制电路和废气监测中使用的方法

    公开(公告)号:US5429105A

    公开(公告)日:1995-07-04

    申请号:US241105

    申请日:1994-05-11

    CPC分类号: G01N27/4065

    摘要: A method and circuit for generating an output signal representative of the pumping current required to equalize the oxygen diffusion between the sensing cell and the pumping cell of an oxygen-ion concentration proportional sensor located in the exhaust system of an internal combustion engine. A replication current, which is isolated from but representative of the pumping current, is generated. The replication current is then passed through a load resistance for generating the output signal. The replication current is generated simultaneously with but isolated from the pumping current, thereby eliminating the need for separate amplification of a sensed version of the pumping current.

    摘要翻译: 一种用于产生代表泵浦电流的输出信号的方法和电路,用于使位于内燃机的排气系统中的氧离子浓度比例传感器的感测单元和泵浦单元之间的氧气扩散相等。 产生与泵浦电流隔离但代表泵浦电流的复制电流。 然后复制电流通过用于产生输出信号的负载电阻。 复制电流与泵浦电流同时产生,但是与泵浦电流隔离,从而消除了对感测型式的泵浦电流的单独放大的需要。

    Therapeutic treatment of fibromyalgia
    9.
    发明授权
    Therapeutic treatment of fibromyalgia 失效
    纤维肌痛的治疗方法

    公开(公告)号:US5378686A

    公开(公告)日:1995-01-03

    申请号:US947792

    申请日:1992-09-21

    申请人: Robert M. Bennett

    发明人: Robert M. Bennett

    IPC分类号: A61K38/27 A61K37/36

    CPC分类号: A61K38/27

    摘要: Disclosed is a therapeutic regime for treating patients with fibromyalgia (FM) and other syndromes characterized by non-restorative sleep and musculoskeletal pain. Supplemental growth hormone (GH) is administered and somatomedin-C (SMC) levels monitored until SMC levels reach optimal levels and musculoskeletal pain and fatiguability symptoms subside.

    摘要翻译: 公开了一种用于治疗纤维肌痛(FM)和其他以非恢复性睡眠和肌肉骨骼疼痛为特征的综合征患者的治疗方案。 给予补充生长激素(GH),监测生长调节素C(SMC)水平,直到SMC水平达到最佳水平,肌肉骨骼疼痛和疲劳症状消退。

    Compositions and methods for enhancing and treating female sexual response
    10.
    发明授权
    Compositions and methods for enhancing and treating female sexual response 有权
    用于增强和治疗女性性反应的组合和方法

    公开(公告)号:US08128972B2

    公开(公告)日:2012-03-06

    申请号:US13010756

    申请日:2011-01-20

    IPC分类号: A01N65/00

    摘要: The present invention relates to compositions, articles of manufacture, methods of preparation thereof, methods of use thereof, etc., for enhancement of sexual pleasure, conditions, disorders, and diseases related to reproductive physiology and systems, especially of mammalian females. For instance, the present invention relates to all aspects of modulating the female sexual response, including female sexual dysfunction, such as female sexual arousal disorders (FSAD), orgasmic disorders, and sexual pain disorders, and enhancing female sexual pleasure and satisfaction of the female sexual experience. Accordingly, the present invention relates to compositions comprising botanical extracts, active agents, etc., which are useful to treat or affect any of the aforementioned conditions. For example, the present invention relates to a composition, preferably for topical or local use, which comprises one or more of the following ingredients, including, but not limited to, borage seed oil, Angelica pubescens root and other angelica species, Coleus forskohlii extract, vinpocetine, ferulic acid, magnesium, ascorbyl palmitate, capric/caprylic triglyceride, silica, and equivalents thereof.

    摘要翻译: 本发明涉及组合物,制品,其制备方法,使用方法等,用于增强性快感,病症,病症以及与生殖生理学和系统特别是哺乳动物雌性有关的疾病。 例如,本发明涉及调节女性性反应的所有方面,包括女性性功能障碍,例如女性性唤起障碍(FSAD),性高潮障碍和性疼痛障碍,以及增强女性性快感和对女性的满意度 性经验。 因此,本发明涉及可用于治疗或影响任何上述病症的植物提取物,活性剂等的组合物。 例如,本发明涉及一种组合物,优选用于局部或局部使用,其包含以下成分中的一种或多种,​​包括但不限于琉璃苣种子油,当归根和当归等,提取物Coleus forskohlii提取物 ,长春西汀,阿魏酸,镁,抗坏血酸棕榈酸酯,癸酸/辛酸甘油三酯,二氧化硅及其等同物。