RAPID ANALYSIS OF ORAL BIOAVAILABILITY
    5.
    发明申请
    RAPID ANALYSIS OF ORAL BIOAVAILABILITY 审中-公开
    口服生物利用率的快速分析

    公开(公告)号:US20080160503A1

    公开(公告)日:2008-07-03

    申请号:US11924505

    申请日:2007-10-25

    IPC分类号: C12Q1/00 G01N33/50 H01J49/00

    CPC分类号: G01N33/6848 Y10T436/24

    摘要: Provided herein are procedures for rapidly determining oral bioavailability of two or more compounds by administering the two or more compounds to an animal, extracting fluid from an eye region of the animal and determining the amount of each of the two or more compounds in the fluid by mass spectrometry. Such procedures can provide cost advantages for determining oral bioavailability as they allow for (i) utilizing relatively small animals, (ii) extracting multiple samples from a single animal, and (iii) analyzing multiple compounds in a single animal, for example.

    摘要翻译: 本文提供了通过将两种或更多种化合物施用于动物来快速测定两种或更多种化合物的口服生物利用度的方法,从动物的眼睛区域中提取液体并通过以下方式确定流体中两种或更多种化合物的量 质谱。 这样的程序可以为确定口服生物利用度提供成本优势,因为它们允许(i)利用相对较小的动物,(ii)从单一动物中提取多个样品,和(iii)分析单个动物中的多种化合物。

    METHODS FOR TREATING OPHTHALMIC DISORDERS
    7.
    发明申请
    METHODS FOR TREATING OPHTHALMIC DISORDERS 审中-公开
    治疗眼底疾病的方法

    公开(公告)号:US20080318939A1

    公开(公告)日:2008-12-25

    申请号:US12143256

    申请日:2008-06-20

    CPC分类号: A61K31/496 A61K31/5383

    摘要: The invention relates in part to methods for treating ophthalmic conditions using compounds described herein. The conditions to be treated include various ocular cancers. The compositions employed include a polycyclic quinolinone derivative or related heteroaromatic analog thereof.

    摘要翻译: 本发明部分地涉及使用本文所述的化合物治疗眼科病症的方法。 待治疗的病症包括各种眼部癌症。 所用的组合物包括多环喹啉酮衍生物或其相关杂芳族类似物。

    METHOD FOR ACHIEVING COMPLIANT SUB-RESOLUTION ASSIST FEATURES
    9.
    发明申请
    METHOD FOR ACHIEVING COMPLIANT SUB-RESOLUTION ASSIST FEATURES 审中-公开
    实现合适分解辅助特征的方法

    公开(公告)号:US20080063948A1

    公开(公告)日:2008-03-13

    申请号:US11531048

    申请日:2006-09-12

    申请人: Sean O'Brien

    发明人: Sean O'Brien

    IPC分类号: G03C5/00 G06F17/50 G03F1/00

    CPC分类号: G03F1/36

    摘要: The present application is directed to a process of forming a photomask pattern comprising one or more sub-resolution assist features (SRAF). The process comprises generating a first set of SRAF patterns. Each of the SRAF patterns in the first set having a first assigned mask position. After the first set of SRAF patterns are generated, determining if the SRAF patterns of the first set comply with a preselected set of rules, wherein one or more of the SRAF patterns are found to be illegal because they do not comply with at least one of the preselected rules. One or more of the illegal SRAF patterns are reassigned to second mask positions that are different from the first mask positions, the second mask positions allowing the illegal SRAF patterns to comply with the at least one preselected rule to form corrected SRAF patterns. The present application also discloses systems for generating a sub-resolution assist feature pattern for a photomask, as well as SRAF modules embodied on a computer readable medium comprising instructions operable to carry out the processes of the present application.

    摘要翻译: 本申请涉及形成包括一个或多个子分辨率辅助特征(SRAF)的光掩模图案的过程。 该过程包括生成第一组SRAF模式。 第一组中的每个SRAF图案具有第一分配的屏蔽位置。 在生成第一组SRAF模式之后,确定第一组的SRAF模式是否符合预选的一组规则,其中发现一个或多个SRAF模式是非法的,因为它们不符合以下中的至少一个: 预选规则。 一个或多个非法SRAF图案被重新分配给与第一掩模位置不同的第二掩模位置,允许非法SRAF图案的第二掩码位置符合至少一个预选规则以形成校正的SRAF图案。 本申请还公开了用于生成用于光掩模的子分辨率辅助特征图案的系统,以及体现在包括可操作以执行本申请的处理的指令的计算机可读介质上的SRAF模块。

    Software and method for advertisor sponsored events within a private centrally managed local or distributed network of users and an optional associated private network card for specialty marketing identification or banking
    10.
    发明申请
    Software and method for advertisor sponsored events within a private centrally managed local or distributed network of users and an optional associated private network card for specialty marketing identification or banking 审中-公开
    私人集中管理的本地或分布式用户网络中的广告赞助活动的软件和方法以及可选的相关专用网卡,用于专业营销识别或银行业务

    公开(公告)号:US20060143084A1

    公开(公告)日:2006-06-29

    申请号:US11319996

    申请日:2005-12-27

    IPC分类号: G06Q30/00

    摘要: The present invention provides a business method, computer system and software that permit a digital media peer-to-peer or server-to-peer exchange, with sponsored media access, while providing a secure and high speed transmission of media files across an internet, intranet or cable network in such a manner as to avoid illegal or un-permitted end user digital file sharing or copying. More particularly, the invention provides a method that combines a digital media encryption technique and unique user key to permit transmission of digital media information in a very compressed or compacted small-size file that is essentially incapable of being decoded without a legitimate user key. The network or virtual private network provides computer hardware, software and at least one interface for advertisers to view marketing factor listings corresponding to network end users and to provide sponsored digital media access for selected listings of end users in exchange for targeted advertising of users.

    摘要翻译: 本发明提供一种商业方法,计算机系统和软件,其允许具有赞助的媒体访问的数字媒体对等或服务器到对等交换,同时在互联网上提供媒体文件的安全和高速传输, 内部网或有线网络,以避免非法或不允许的最终用户数字文件共享或复制。 更具体地,本发明提供了一种组合数字媒体加密技术和唯一用户密钥以允许在非压缩或压缩的小尺寸文件中传输数字媒体信息的方法,该小型文件基本上不能在没有合法用户密钥的情况下进行解码。 网络或虚拟专用网络为广告商提供计算机硬件,软件和至少一个接口,以查看与网络终端用户相对应的营销因素列表,并为最终用户的选定列表提供赞助的数字媒体访问,以换取用户的有针对性的广告。