公开(公告)号：US07647836B2

公开(公告)日：2010-01-19

申请号：US11748803

申请日：2007-05-15

申请人： David O'Brien ,  Christophe Courcimault ,  Liang You ,  Mark Allen ,  Michael Fonseca ,  Florent Cros

发明人： David O'Brien ,  Christophe Courcimault ,  Liang You ,  Mark Allen ,  Michael Fonseca ,  Florent Cros

IPC分类号： G01L7/00

CPC分类号： G01L9/0075 ,  G01L9/0042 ,  G01L9/0055 ,  Y10T29/49002

摘要： A pressure cavity is durable, stable, and biocompatible and configured in such a way that it constitutes pico to nanoliter-scale volume. The pressure cavity is hermetically sealed from the exterior environment while maintaining the ability to communicate with other devices. Micromachined, hermetically-sealed sensors are configured to receive power and return information through direct electrical contact with external electronics. The pressure cavity and sensor components disposed therein are hermetically sealed from the ambient in order to reduce drift and instability within the sensor. The sensor is designed for harsh and biological environments, e.g. intracorporeal implantation and in vivo use. Additionally, novel manufacturing methods are employed to construct the sensors.

摘要翻译： 压力腔是耐用的，稳定的和生物相容的并且被配置成使得其构成微微至纳升级体积的量。 压力腔与外部环境密封，同时保持与其他设备通信的能力。 微加工的密封传感器配置为通过与外部电子设备的直接电气接触来接收电力并返回信息。 设置在其中的压力腔和传感器部件与环境密封，以便减少传感器内的漂移和不稳定性。 传感器设计用于苛刻和生物环境，例如 体内植入和体内使用。 另外，采用新的制造方法构造传感器。

公开(公告)号：US20070107524A1

公开(公告)日：2007-05-17

申请号：US11582669

申请日：2006-10-18

申请人： David O'Brien ,  Christophe Courcimault ,  Liang You ,  Yeun-Ho Joung ,  Mark Allen

发明人： David O'Brien ,  Christophe Courcimault ,  Liang You ,  Yeun-Ho Joung ,  Mark Allen

IPC分类号： G01L9/00

CPC分类号： G01L9/0073

摘要： An exemplary pressure cavity is disclosed that is durable, stable, and biocompatible and configured in such a way that it constitutes pico to nanoliter-scale volume. The exemplary pressure cavity is hermetically sealed from the exterior environment while maintaining the ability to communicate with other devices. Micromachined, hermetically-sealed sensors are configured to receive power and return information through direct electrical contact with external electronics. The pressure cavity and sensor components disposed therein are hermetically sealed from ambient pressure in order to reduce drift and instability within the sensor. The sensor is designed for harsh and biological environments, e.g., intracorporeal implantation and in vivo use. Additionally, novel manufacturing methods are employed to construct the sensors.

摘要翻译： 公开了一种示例性的压力腔，其是耐用的，稳定的和生物相容的并且以这样的方式配置，使得其构成微微至纳升级体积。 示例性压力腔与外部环境气密密封，同时保持与其他装置通信的能力。 微加工的密封传感器配置为通过与外部电子设备的直接电气接触来接收电力并返回信息。 设置在其中的压力腔和传感器部件与环境压力密封，以减少传感器内的漂移和不稳定性。 传感器设计用于恶劣和生物环境，例如体内植入和体内使用。 另外，采用新的制造方法构造传感器。

公开(公告)号：US07748277B2

公开(公告)日：2010-07-06

申请号：US11582669

申请日：2006-10-18

申请人： David O'Brien ,  Christophe Courcimault ,  Liang You ,  Yeun-Ho Joung ,  Mark Allen

发明人： David O'Brien ,  Christophe Courcimault ,  Liang You ,  Yeun-Ho Joung ,  Mark Allen

IPC分类号： G01L9/00 ,  G01L9/12 ,  G01L9/06

CPC分类号： G01L9/0073

摘要： An exemplary pressure cavity is disclosed that is durable, stable, and biocompatible and configured in such a way that it constitutes pico to nanoliter-scale volume. The exemplary pressure cavity is hermetically sealed from the exterior environment while maintaining the ability to communicate with other devices. Micromachined, hermetically-sealed sensors are configured to receive power and return information through direct electrical contact with external electronics. The pressure cavity and sensor components disposed therein are hermetically sealed from ambient pressure in order to reduce drift and instability within the sensor. The sensor is designed for harsh and biological environments, e.g., intracorporeal implantation and in vivo use. Additionally, novel manufacturing methods are employed to construct the sensors.

摘要翻译： 公开了一种示例性的压力腔，其是耐用的，稳定的和生物相容的并且以这样的方式配置，使得其构成微微至纳升级体积。 示例性压力腔与外部环境气密密封，同时保持与其他装置通信的能力。 微加工的密封传感器配置为通过与外部电子设备的直接电气接触来接收电力并返回信息。 设置在其中的压力腔和传感器部件与环境压力密封，以减少传感器内的漂移和不稳定性。 传感器设计用于恶劣和生物环境，例如体内植入和体内使用。 另外，采用新的制造方法构造传感器。

公开(公告)号：US20070261497A1

公开(公告)日：2007-11-15

申请号：US11748803

申请日：2007-05-15

申请人： David O'Brien ,  Christophe Courcimault ,  Liang You

发明人： David O'Brien ,  Christophe Courcimault ,  Liang You

IPC分类号： G01L9/12 ,  G01L7/00

CPC分类号： G01L9/0075 ,  G01L9/0042 ,  G01L9/0055 ,  Y10T29/49002

摘要： A pressure cavity is durable, stable, and biocompatible and configured in such a way that it constitutes pico to nanoliter-scale volume. The pressure cavity is hermetically sealed from the exterior environment while maintaining the ability to communicate with other devices. Mi cromachined, hermetically-sealed sensors are configured to receive power and return information through direct electrical contact with external electronics. The pressure cavity and sensor components disposed therein are hermetically sealed from the ambient in order to reduce drift and instability within the sensor. The sensor is designed for harsh and biological environments, e.g. intracorporeal implantation and in vivo use. Additionally, novel manufacturing methods are employed to construct the sensors.

摘要翻译： 压力腔是耐用的，稳定的和生物相容的并且被配置成使得其构成微微至纳升级体积的量。 压力腔与外部环境密封，同时保持与其他设备通信的能力。 密封的密封传感器配置为通过与外部电子设备的直接电气接触来接收电力和返回信息。 设置在其中的压力腔和传感器部件与环境密封，以便减少传感器内的漂移和不稳定性。 传感器设计用于苛刻和生物环境，例如 体内植入和体内使用。 另外，采用新的制造方法构造传感器。

公开(公告)号：US20090278553A1

公开(公告)日：2009-11-12

申请号：US12416904

申请日：2009-04-01

申请人： Jason Kroh ,  Florent Cros ,  Christophe Courcimault

发明人： Jason Kroh ,  Florent Cros ,  Christophe Courcimault

IPC分类号： G01R27/04 ,  G01R27/28

CPC分类号： A61B5/055 ,  A61B5/0031 ,  A61B5/05 ,  A61B5/076 ,  A61B5/4514 ,  A61B2560/0219 ,  A61B2560/0223 ,  H01Q7/00

摘要： A system and apparatus for providing an in-vivo assessment of relative movement of an implant that is positioned in a living being is provided that comprises a first assembly and a second assembly that are positioned within the living being. The first assembly comprises a passive electrical resonant circuit that is configured to be selectively electromagnetically coupled to an ex-vivo source of RF energy and, in response to the electromagnetic coupling, generates an output signal characterized by a frequency that is dependent upon a distance between the first assembly and the second assembly at the time of the electromagnetic coupling.

摘要翻译： 提供了一种用于提供对位于生物体内的植入物的相对运动的体内评估的系统和装置，其包括位于生物体内的第一组件和第二组件。 第一组件包括无源电谐振电路，其被配置为选择性地电磁耦合到离体RF能量源，并且响应于电磁耦合，产生以由频率表示的频率的输出信号，该频率取决于 第一组件和第二组件在电磁耦合时。

公开(公告)号：US08278941B2

公开(公告)日：2012-10-02

申请号：US12416916

申请日：2009-04-01

申请人： Jason Kroh ,  Florent Cros ,  Christophe Courcimault

发明人： Jason Kroh ,  Florent Cros ,  Christophe Courcimault

IPC分类号： G01R27/02

CPC分类号： G01L9/0073 ,  A61B5/0031 ,  A61B5/076 ,  A61B5/1116 ,  A61B5/4504 ,  A61B5/686 ,  A61B17/7002 ,  A61B2017/00221 ,  A61B2560/0219 ,  A61B2560/0223 ,  A61B2562/0261 ,  G01F15/066 ,  G01L1/14 ,  H01Q7/00

摘要： This application relates to an apparatus and system for sensing strain on a portion of an implant positioned in a living being. In one aspect, the apparatus has at least one sensor assembly that can be mountable thereon a portion of the implant and that has a passive electrical resonant circuit that can be configured to be selectively electromagnetically coupled to an ex-vivo source of RF energy. Each sensor assembly, in response to the electromagnetic coupling, can be configured to generate an output signal characterized by a frequency that is dependent upon urged movement of a portion of the passive electrical resonant circuit and is indicative of strain applied thereon a portion of the respective sensor assembly.

摘要翻译： 本申请涉及用于感测定位在生物体内的植入物的一部分上的应变的装置和系统。 在一个方面，该装置具有至少一个传感器组件，其可以安装在其上的植入物的一部分上，并且具有无源电谐振电路，其可被配置为选择性地电磁耦合到离体RF能量源。 响应于电磁耦合，每个传感器组件可被配置成产生一个输出信号，该输出信号的特征在于取决于被动电谐振电路的一部分被推动的移动的频率，并且指示施加在其上的相应的一部分的应变 传感器组件。

公开(公告)号：US08026729B2

公开(公告)日：2011-09-27

申请号：US12416904

申请日：2009-04-01

申请人： Jason Kroh ,  Florent Cros ,  Christophe Courcimault

发明人： Jason Kroh ,  Florent Cros ,  Christophe Courcimault

IPC分类号： G01R27/04

CPC分类号： A61B5/055 ,  A61B5/0031 ,  A61B5/05 ,  A61B5/076 ,  A61B5/4514 ,  A61B2560/0219 ,  A61B2560/0223 ,  H01Q7/00

摘要： A system and apparatus for providing an in-vivo assessment of relative movement of an implant that is positioned in a living being is provided that includes a first assembly and a second assembly that are positioned within the living being. The first assembly includes a passive electrical resonant circuit that is configured to be selectively electromagnetically coupled to an ex-vivo source of RF energy and, in response to the electromagnetic coupling, generates an output signal characterized by a frequency that is dependent upon a distance between the first assembly and the second assembly at the time of the electromagnetic coupling.

摘要翻译： 提供了一种用于提供定位在生活中的植入物的相对运动的体内评估的系统和装置，其包括位于生物体内的第一组件和第二组件。 第一组件包括无源电谐振电路，其被配置为选择性地电磁耦合到离体RF能量源，并且响应于电磁耦合，产生以由频率表示的频率的输出信号，该频率取决于 第一组件和第二组件在电磁耦合时。

公开(公告)号：US20120016228A1

公开(公告)日：2012-01-19

申请号：US13245553

申请日：2011-09-26

申请人： Jason Kroh ,  Florent Cros ,  Christophe Courcimault

发明人： Jason Kroh ,  Florent Cros ,  Christophe Courcimault

IPC分类号： A61B5/05

CPC分类号： A61B5/055 ,  A61B5/0031 ,  A61B5/05 ,  A61B5/076 ,  A61B5/4514 ,  A61B2560/0219 ,  A61B2560/0223 ,  H01Q7/00

摘要： A method for providing an in-vivo assessment of relative movement of an implant that is positioned in a living being is provided that comprises a first assembly and a second assembly that are positioned within the living being. The first assembly comprises a passive electrical resonant circuit that is configured to be selectively electromagnetically coupled to an ex-vivo source of RF energy and, in response to the electromagnetic coupling, generates an output signal characterized by a frequency that is dependent upon a distance between the first assembly and the second assembly at the time of the electromagnetic coupling.

摘要翻译： 提供了一种用于提供对位于生物中的植入物的相对运动的体内评估的方法，其包括位于生物体内的第一组件和第二组件。 第一组件包括无源电谐振电路，其被配置为选择性地电磁耦合到离体RF能量源，并且响应于电磁耦合，产生以由频率表示的频率的输出信号，该频率取决于 第一组件和第二组件在电磁耦合时。

公开(公告)号：US20090273353A1

公开(公告)日：2009-11-05

申请号：US12416916

申请日：2009-04-01

申请人： Jason Kroh ,  Florent Cros ,  Christophe Courcimault

发明人： Jason Kroh ,  Florent Cros ,  Christophe Courcimault

IPC分类号： G01L1/00 ,  G01R27/28

CPC分类号： G01L9/0073 ,  A61B5/0031 ,  A61B5/076 ,  A61B5/1116 ,  A61B5/4504 ,  A61B5/686 ,  A61B17/7002 ,  A61B2017/00221 ,  A61B2560/0219 ,  A61B2560/0223 ,  A61B2562/0261 ,  G01F15/066 ,  G01L1/14 ,  H01Q7/00

摘要： This application relates to an apparatus and system for sensing strain on a portion of an implant positioned in a living being. In one aspect, the apparatus has at least one sensor assembly that can be mountable thereon a portion of the implant and that has a passive electrical resonant circuit that can be configured to be selectively electromagnetically coupled to an ex-vivo source of RF energy. Each sensor assembly, in response to the electromagnetic coupling, can be configured to generate an output signal characterized by a frequency that is dependent upon urged movement of a portion of the passive electrical resonant circuit and is indicative of strain applied thereon a portion of the respective sensor assembly.

摘要翻译： 本申请涉及用于感测定位在生物体内的植入物的一部分上的应变的装置和系统。 在一个方面，该装置具有至少一个传感器组件，其可以安装在其上的植入物的一部分上，并且具有无源电谐振电路，其可被配置为选择性地电磁耦合到离体RF能量源。 响应于电磁耦合，每个传感器组件可被配置成产生一个输出信号，该输出信号的特征在于取决于被动电谐振电路的一部分被推动的移动的频率，并且指示施加在其上的相应的一部分的应变 传感器组件。

公开(公告)号：US08896324B2

公开(公告)日：2014-11-25

申请号：US13245553

申请日：2011-09-26

申请人： Jason Kroh ,  Florent Cros ,  Christophe Courcimault

发明人： Jason Kroh ,  Florent Cros ,  Christophe Courcimault

IPC分类号： G01R27/04 ,  A61B5/055 ,  A61B5/00 ,  A61B5/05 ,  H01Q7/00 ,  A61B5/07

CPC分类号： A61B5/055 ,  A61B5/0031 ,  A61B5/05 ,  A61B5/076 ,  A61B5/4514 ,  A61B2560/0219 ,  A61B2560/0223 ,  H01Q7/00

摘要： A method for providing an in-vivo assessment of relative movement of an implant that is positioned in a living being is provided wherein a first assembly and a second assembly are positioned within the living being. The first assembly includes a passive electrical resonant circuit that is configured to be selectively electromagnetically coupled to an ex-vivo source of RF energy and, in response to the electromagnetic coupling, generates an output signal characterized by a frequency that is dependent upon a distance between the first assembly and the second assembly at the time of the electromagnetic coupling.

摘要翻译： 提供了一种用于提供对位于生物体内的植入体的相对运动的体内评估的方法，其中第一组件和第二组件位于生物体内。 第一组件包括无源电谐振电路，其被配置为选择性地电磁耦合到离体RF能量源，并且响应于电磁耦合，产生以由频率表示的频率的输出信号，该频率取决于 第一组件和第二组件在电磁耦合时。