摘要:
The present invention is directed to a novel process for the preparation of substituted triazole compounds, useful in the treating or ameliorating a selective kinase or dual-kinase mediated disorder. The process of the present invention preferentially produces the desired regioisomer of the substituted triazole compounds.
摘要:
The present invention is directed to novel processes for the preparation of substituted piperazinyl and diazepanyl benzamides, useful for the treatment of disorders and conditions mediated by the histamine receptor.
摘要:
The present invention is directed to novel processes for the preparation of cyclopropyl-amide derivatives, useful for the treatment of disorders and conditions mediated by the histamine receptor.
摘要:
An improved wheel cover for large commercial vehicle trailers is disclosed. It includes simple and robust mechanism for attachment with the wheel, facilitates easy installation and removal, and provides better aerodynamics and fuel efficiency during travel. In a preferred embodiment, an annular flexible shell cover (covering an annular magnet) of the wheel cover, deforms and frictionally fits into hollow of a corresponding wheel flange, and the annular magnet (lying under the shell cover) keeps the shell cover magnetically attached (with a strong magnetic bonding) with the flange. Hence, in addition to the magnetic bonding, the installed wheel cover is held in place by a friction fitting between the shell cover and the flange. The outer side of the wheel cover can either be kept planar or curved, and its surface can be dimpled or smooth.
摘要:
An apparatus for supporting an object on the frame structure (chassis) of a vehicle includes a U-shaped top bracket and an L-shaped bottom bracket. To mount the apparatus onto the frame structure, the top bracket is first positioned and held against the frame structure. A tongue on the bottom bracket is then inserted through a slot in the top bracket, and a bolt on the bottom bracket is inserted through an aperture in the top bracket. A nut is then screwed onto the bolt, and tightened to hold the apparatus around the frame structure. Sizing inserts can be appropriately positioned between the apparatus and the frame structure, and the top bracket can include a mounting plate for supporting the object.
摘要:
Various techniques are disclosed for facilitating gesture-based interactions with intelligent multi-player electronic gaming systems which include a multi-user, multi-touch input display surface capable of concurrently supporting contact-based and/or non-contact-based gestures performed by one or more users at or near the input display surface. Gestures may include single touch, multi-touch, and/or near-touch gestures. Some gaming system embodiments may include automated hand tracking functionality for identifying and/or tracking the hands of users interacting with the display surface. In some gaming system embodiments, the multi-user, multi-touch input display surface may be implemented using a multi-layered display (MLD) display device which includes multiple layered display screens. Various types of MLD-related display techniques disclosed herein may be advantageously used for facilitating gesture-based user interactions with a MLD-based multi-user, multi-touch input display surface and/or for facilitating various types of activities conducted at the gaming system, including, for example, various types of game-related and/or wager-related activities. According to various embodiments, users interacting with the multi-user, multi-touch input display surface may convey game play instructions, wagering instructions, and/or other types of instructions to the gaming system by performing various types of gestures at or over the multi-user, multi-touch input display surface. In some embodiments, the gaming system may include gesture processing functionality for: detecting users' gestures, identifying the user who performed a detected gesture, recognizing the gesture, interpreting the gesture, mapping the gesture to one or more appropriate function(s), and/or initiating the function(s). In at least some embodiments, such gesture processing may take into account various external factors, conditions, and/or information which, for example, may facilitate proper and/or appropriate gesture recognition, gesture interpretation, and/or gesture-function mapping.
摘要:
The present invention is directed to a manual bulk liquid pump control and distribution system that utilizes a single-handle manual operation for direction of flow and speed, along with providing a neutral position for standby. The system can be operated at a rate of 0 to 250 gallons per minute and be reversed with a single motion of the operating handle. The pump operates in one direction at a fixed RPM, resulting in longer pump life and safer operation. For added safety, the system utilizes the pump's relief valve for both discharge and suction operation. It has the ability of sucking the liquid out of the lines and hoses after each transfer operation. This system has an aluminum flow-reversing valve or two-way valve at the center of the design. This valve allows the flow of the product to be precisely controlled in either direction, along with the flow rate and pressure. This gives the operator the ability to control the product regardless of viscosity or volume. The system has been designed with pressure-tested manifolds and custom design brackets along with a sampling valve and an easily accessible angled strainer basket. The design allows for safe and convenient pump operation as well as for the proper handling of liquids during environmentally sensitive times.
摘要:
The present invention is directed to a novel process for the preparation of piperazinyl and diazepanyl benzamide derivatives, useful for the treatment of disorders and conditions mediated by a histamine receptor, preferably the H3 receptor.
摘要:
The present invention is directed to a manual bulk liquid pump control and distribution system that utilizes a single-handle manual operation for direction of flow and speed, along with providing a neutral position for standby. The system can be operated at a rate of 0 to 250 gallons per minute and be reversed with a single motion of the operating handle. The pump operates in one direction at a fixed RPM, resulting in longer pump life and safer operation. For added safety, the system utilizes the pump's relief valve for both discharge and suction operation. It has the ability of sucking the liquid out of the lines and hoses after each transfer operation. This system has an aluminum flow-reversing valve or two-way valve at the center of the design. This valve allows the flow of the product to be precisely controlled in either direction, along with the flow rate and pressure. This gives the operator the ability to control the product regardless of viscosity or volume. The system has been designed with pressure-tested manifolds and custom design brackets along with a sampling valve and an easily accessible angled strainer basket. The design allows for safe and convenient pump operation as well as for the proper handling of liquids during environmentally sensitive times.