-
公开(公告)号：US08409564B2
公开(公告)日：2013-04-02
申请号：US10969011
申请日：2004-10-21
IPC分类号： A61K41/00 , C07D311/82 , C12N13/00
CPC分类号： A61K41/0009 , A61K41/0057 , C07D311/82 , C12N5/0087
摘要： The present invention relates to the use of the photoactivable derivatives for the photodynamic treatment for the selective destruction and/or inactivation of immunologically reactive cells without affecting the normal cells and without causing systemic toxicity for the patient, wherein appropriate intracellular levels of said derivatives are achieved and irradiation of a suitable wavelength and intensity is applied.
摘要翻译： 本发明涉及可光活化衍生物用于光动力学治疗用于免疫反应性细胞的选择性破坏和/或灭活而不影响正常细胞并且不对患者造成全身毒性的用途，其中实现所述衍生物的适当的细胞内水平 并施加合适的波长和强度的照射。
-
公开(公告)号：US20060088507A1
公开(公告)日：2006-04-27
申请号：US10969011
申请日：2004-10-21
IPC分类号： A61K35/14 , A61K31/365
CPC分类号： A61K41/0009 , A61K41/0057 , C07D311/82 , C12N5/0087
摘要： The present invention relates to the use of the photoactivable derivatives for the photodynamic treatment for the selective destruction and/or inactivation of immunologically reactive cells without affecting the normal cells and without causing systemic toxicity for the patient, wherein appropriate intracellular levels of said derivatives are achieved and irradiation of a suitable wavelength and intensity is applied.
-
公开(公告)号：US20120328606A1
公开(公告)日：2012-12-27
申请号：US13474459
申请日：2012-05-17
IPC分类号： A61K39/395 , G06F19/00 , A61P9/00
CPC分类号： G01N33/56972 , G01N2800/12 , G01N2800/52 , G01N2800/60 , G06F19/00 , G06F19/3456 , G16H50/20
摘要： The present disclosure provides methods of diagnosing a subject as having a pulmonary disease or disorder, e.g., an eosinophilic disease or disorder based on the determination of white blood cell ratios. The disclosure also provides white blood cell ratio-based methods of treating, prognosing, or monitoring a pulmonary disease or disorder, as well as methods of methods of predicting a dosage regimen, identifying a candidate therapeutic agent, identifying a patient as a candidate for a therapeutic agent, and methods of designing a personalized therapy.
摘要翻译： 本公开提供了基于白细胞比率的确定将受试者诊断为具有肺部疾病或病症，例如嗜酸细胞性疾病或病症的方法。 本公开还提供了基于白细胞比例的治疗，预后或监测肺部疾病或病症的方法，以及预测剂量方案的方法，鉴定候选治疗剂，鉴定患者作为候选治疗剂的候选者 治疗剂和设计个性化疗法的方法。
-
公开(公告)号：US08961965B2
公开(公告)日：2015-02-24
申请号：US13474459
申请日：2012-05-17
IPC分类号： A61K39/395 , G01N33/569 , G06F19/00
CPC分类号： G01N33/56972 , G01N2800/12 , G01N2800/52 , G01N2800/60 , G06F19/00 , G06F19/3456 , G16H50/20
摘要： The present disclosure provides methods of diagnosing a subject as having a pulmonary disease or disorder, e.g., an eosinophilic disease or disorder based on the determination of white blood cell ratios. The disclosure also provides white blood cell ratio-based methods of treating, prognosing, or monitoring a pulmonary disease or disorder, as well as methods of methods of predicting a dosage regimen, identifying a candidate therapeutic agent, identifying a patient as a candidate for a therapeutic agent, and methods of designing a personalized therapy.
摘要翻译： 本公开提供了基于白细胞比率的确定将受试者诊断为具有肺部疾病或病症，例如嗜酸细胞性疾病或病症的方法。 本公开还提供了基于白细胞比例的治疗，预后或监测肺部疾病或病症的方法，以及预测剂量方案的方法，鉴定候选治疗剂，鉴定患者作为候选治疗剂的候选者 治疗剂和设计个性化疗法的方法。
-
-
-
搜索结果
4 条记录 (耗时 0.024 秒)
