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    Antiviral drugs for treatment of arenavirus infection
    2.
    发明授权
    Antiviral drugs for treatment of arenavirus infection 有权
    用于治疗斑马鱼病毒感染的抗病毒药物

    公开(公告)号：US08148428B2

    公开(公告)日：2012-04-03

    申请号：US12281081

    申请日：2007-03-02

    申请人： Dennis E. Hruby ,  Tove C. Bolken ,  Sean Amberg ,  Dongcheng Dai

    发明人： Dennis E. Hruby ,  Tove C. Bolken ,  Sean Amberg ,  Dongcheng Dai

    IPC分类号： A61K31/16

    CPC分类号： C07C251/86 ,  A61K31/165 ,  A61K31/343 ,  C07C251/76 ,  C07C251/82 ,  C07C2601/02 ,  C07C2601/14 ,  C07C2603/20 ,  C07D209/40 ,  C07D307/68 ,  C07D333/22 ,  C07D333/38 ,  Y02A50/387 ,  Y02A50/397

    摘要： Compounds, methods and pharmaceutical compositions for treating viral infections, by administering certain novel compounds in therapeutically effective amounts are disclosed. Methods for preparing the compounds and methods of using the compounds and pharmaceutical compositions thereof are also disclosed. In particular, the treatment and prophylaxis of viral infections such as caused by hemorrhagic fever viruses is disclosed, i.e., including but not limited to, Arenaviridae (Junin, Machupo, Guanarito, Sabia, Lassa, Tacaribe, and Pichinde), Filoviridae (Ebola and Marburg viruses), Flaviviridae (yellow fever, Omsk hemorrhagic fever and Kyasanur Forest disease viruses), and Bunyaviridae (Rift Valley fever).

    摘要翻译： 公开了通过施用治疗有效量的某些新化合物来治疗病毒感染的化合物，方法和药物组合物。 还公开了制备化合物的方法和使用该化合物的方法及其药物组合物。 特别地，公开了治疗和预防由出血热病毒引起的病毒感染，即，包括但不限于：链球菌科（Junin，Machupo，Guanarito，Sabia，Lassa，Tacaribe和Pichinde），丝状病毒科（埃博拉 马尔堡病毒），黄病毒科（黄热病，鄂木斯克出血热和Kyasanur森林病毒）和布尼瓦病毒（裂谷热）。

    Antiviral drugs for treatment of arenavirus infection
    4.
    发明授权
    Antiviral drugs for treatment of arenavirus infection 有权
    用于治疗斑马鱼病毒感染的抗病毒药物

    公开(公告)号：US07977365B2

    公开(公告)日：2011-07-12

    申请号：US12111778

    申请日：2008-04-29

    申请人： Dennis E. Hruby ,  Tove C. Bolken ,  Sean Amberg ,  Dongcheng Dai ,  Ryan A. Larson

    发明人： Dennis E. Hruby ,  Tove C. Bolken ,  Sean Amberg ,  Dongcheng Dai ,  Ryan A. Larson

    IPC分类号： A61K31/415

    CPC分类号： A61K31/4164 ,  C07D235/06 ,  Y02A50/387 ,  Y02A50/397

    摘要： Compounds, methods and pharmaceutical compositions for treating viral infections, by administering certain novel compounds in therapeutically effective amounts are disclosed. Methods for preparing the compounds and methods of using the compounds and pharmaceutical compositions thereof are also disclosed. In particular, the treatment and prophylaxis of viral infections such as caused by hemorrhagic fever viruses is disclosed, i.e., including but not limited to, Arenaviridae (Junin, Machupo, Guanarito, Sabia, Lassa, Tacaribe, Pichinde, and LCMV), Filoviridae (Ebola and Marburg viruses), Flaviviridae (yellow fever, Omsk hemorrhagic fever and Kyasanur Forest disease viruses), and Bunyaviridae (Rift Valley fever and Crimean-Congo hemorrhagic fever).

    摘要翻译： 公开了通过施用治疗有效量的某些新化合物来治疗病毒感染的化合物，方法和药物组合物。 还公开了制备化合物的方法和使用该化合物的方法及其药物组合物。 具体地，公开了治疗和预防由出血热病毒引起的病毒感染，即，包括但不限于：金杆菌科（Junin，Machupo，Guanarito，Sabia，Lassa，Tacaribe，Pichinde和LCMV），丝状病毒科 埃博拉病毒和马尔堡病毒），黄病毒科（黄热病，鄂木斯克出血热和Kyasanur森林病毒）和布尼亚病毒科（裂谷热和克里米亚 - 刚果出血热）。

    ANTIVIRAL DRUGS FOR TREATMENT OF ARENAVRUS INFECTION
    5.
    发明申请
    ANTIVIRAL DRUGS FOR TREATMENT OF ARENAVRUS INFECTION 有权
    用于治疗ARENAVRUS感染的抗病毒药物

    公开(公告)号：US20080300265A1

    公开(公告)日：2008-12-04

    申请号：US12111778

    申请日：2008-04-29

    申请人： Dennis E. Hruby ,  Tove C. Bolken ,  Sean Amberg ,  Dongcheng Dai ,  Ryan A. Larson

    发明人： Dennis E. Hruby ,  Tove C. Bolken ,  Sean Amberg ,  Dongcheng Dai ,  Ryan A. Larson

    IPC分类号： A61K31/513 ,  A61K31/4184 ,  A61P31/12

    CPC分类号： A61K31/4164 ,  C07D235/06 ,  Y02A50/387 ,  Y02A50/397

    摘要： Compounds, methods and pharmaceutical compositions for treating viral infections, by administering certain novel compounds in therapeutically effective amounts are disclosed. Methods for preparing the compounds and methods of using the compounds and pharmaceutical compositions thereof are also disclosed. In particular, the treatment and prophylaxis of viral infections such as caused by hemorrhagic fever viruses is disclosed, i.e., including but not limited to, Arenaviridae (Junin, Machupo, Guanarito, Sabia, Lassa, Tacaribe, Pichinde, and LCMV), Filoviridae (Ebola and Marburg viruses), Flaviviridae (yellow fever, Omsk hemorrhagic fever and Kyasanur Forest disease viruses), and Bunyaviridae (Rift Valley fever and Crimean-Congo hemorrhagic fever).

    摘要翻译： 公开了通过施用治疗有效量的某些新化合物来治疗病毒感染的化合物，方法和药物组合物。 还公开了制备化合物的方法和使用该化合物的方法及其药物组合物。 具体地，公开了治疗和预防由出血热病毒引起的病毒感染，即，包括但不限于：金杆菌科（Junin，Machupo，Guanarito，Sabia，Lassa，Tacaribe，Pichinde和LCMV），丝状病毒科 埃博拉病毒和马尔堡病毒），黄病毒科（黄热病，鄂木斯克出血热和Kyasanur森林病毒）和布尼亚病毒科（裂谷热和克里米亚 - 刚果出血热）。

    Antiviral drugs for treatment of arenavirus infection
    7.
    发明授权
    Antiviral drugs for treatment of arenavirus infection 有权
    用于治疗斑马鱼病毒感染的抗病毒药物

    公开(公告)号：US07872037B2

    公开(公告)日：2011-01-18

    申请号：US11712918

    申请日：2007-03-02

    申请人： Dennis E. Hruby ,  Tové C. Bolken ,  Sean Amberg ,  Dongcheng Dai

    发明人： Dennis E. Hruby ,  Tové C. Bolken ,  Sean Amberg ,  Dongcheng Dai

    IPC分类号： A61K31/4164 ,  A61P31/14

    CPC分类号： C07D235/06 ,  A61K31/4164 ,  Y02A50/387 ,  Y02A50/397

    摘要： Compounds, methods and pharmaceutical compositions for treating viral infections, by administering certain novel compounds in therapeutically effective amounts are disclosed. Methods for preparing the compounds and methods of using the compounds and pharmaceutical compositions thereof are also disclosed. In particular, the treatment and prophylaxis of viral infections such as caused by hemorrhagic fever viruses is disclosed, i.e., including but not limited to, Arenaviridae (Junin, Machupo, Guanarito, Sabia, Lassa, Tacaribe, Pichinde, and LCMV), Filoviridae (Ebola and Marburg viruses), Flaviviridae (yellow fever, Omsk hemorrhagic fever and Kyasanur Forest disease viruses), and Bunyaviridae (Rift Valley fever).

    摘要翻译： 公开了通过施用治疗有效量的某些新化合物来治疗病毒感染的化合物，方法和药物组合物。 还公开了制备化合物的方法和使用该化合物的方法及其药物组合物。 具体地，公开了治疗和预防由出血热病毒引起的病毒感染，即，包括但不限于：金杆菌科（Junin，Machupo，Guanarito，Sabia，Lassa，Tacaribe，Pichinde和LCMV），丝状病毒科 埃博拉病毒和马尔堡病毒），黄病毒科（黄热病，鄂木斯克出血热和Kyasanur森林病毒）和布亚病毒科（裂谷热）。

    Antiviral drugs for treatment of arenavirus infection
    8.
    发明申请
    Antiviral drugs for treatment of arenavirus infection 有权
    用于治疗斑马鱼病毒感染的抗病毒药物

    公开(公告)号：US20070254934A1

    公开(公告)日：2007-11-01

    申请号：US11712918

    申请日：2007-03-02

    申请人： Dennis Hruby ,  Tove Bolken ,  Sean Amberg ,  Dongcheng Dai

    发明人： Dennis Hruby ,  Tove Bolken ,  Sean Amberg ,  Dongcheng Dai

    IPC分类号： A61K31/4164 ,  A61P31/14 ,  C07D235/04

    CPC分类号： C07D235/06 ,  A61K31/4164 ,  Y02A50/387 ,  Y02A50/397

    摘要： Compounds, methods and pharmaceutical compositions for treating viral infections, by administering certain novel compounds in therapeutically effective amounts are disclosed. Methods for preparing the compounds and methods of using the compounds and pharmaceutical compositions thereof are also disclosed. In particular, the treatment and prophylaxis of viral infections such as caused by hemorrhagic fever viruses is disclosed, i.e., including but not limited to, Arenaviridae (Junin, Machupo, Guanarito, Sabia, Lassa, Tacaribe, Pichinde, and LCMV), Filoviridae (Ebola and Marburg viruses), Flaviviridae (yellow fever, Omsk hemorrhagic fever and Kyasanur Forest disease viruses), and Bunyaviridae (Rift Valley fever).

    摘要翻译： 公开了通过施用治疗有效量的某些新化合物来治疗病毒感染的化合物，方法和药物组合物。 还公开了制备化合物的方法和使用该化合物的方法及其药物组合物。 具体地，公开了治疗和预防由出血热病毒引起的病毒感染，即，包括但不限于：金杆菌科（Junin，Machupo，Guanarito，Sabia，Lassa，Tacaribe，Pichinde和LCMV），丝状病毒科 埃博拉病毒和马尔堡病毒），黄病毒科（黄热病，鄂木斯克出血热和Kyasanur森林病毒）和布亚病毒科（裂谷热）。