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公开(公告)号：US20110159087A1
公开(公告)日：2011-06-30
申请号：US13060624
申请日：2009-09-02
申请人： Dhananjay Govind Sathe , Harish Kashinath Mondkar , Mantripragada Narayan Rao , Samadhan Daulat Patil , Tanaji Shamrao Jadhav , Ashok Omray , Varsha Shashank Choudhary , Yogesh Sharad Bhide
发明人： Dhananjay Govind Sathe , Harish Kashinath Mondkar , Mantripragada Narayan Rao , Samadhan Daulat Patil , Tanaji Shamrao Jadhav , Ashok Omray , Varsha Shashank Choudhary , Yogesh Sharad Bhide
IPC分类号： A61K9/48 , A61K31/785 , A61K9/14 , A61K9/20 , C08G73/02 , A61P3/00 , B02C23/18 , B32B5/00 , A61K9/28 , B29C43/02 , B65B1/20
CPC分类号： A61K31/785 , A61K9/2018 , A61K9/2027 , A61K9/2866 , Y10T428/2982
摘要： Disclosed herein are pharmaceutical compositions comprising wet granulated bile acid sequestrants having the general Formula I shown, and their process of preparation. The present invention also discloses process for preparation of Colesevelam hydrochloride, an antilipemic agent.
摘要翻译： 本文公开了包含具有所示通式I的湿法制粒胆固醇螯合剂及其制备方法的药物组合物。 本发明还公开了制备盐酸考利司他的方法，其是抗血药剂。
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2.发明申请公开(公告)号：US20090280178A1
公开(公告)日：2009-11-12
申请号：US12377129
申请日：2007-08-31
申请人： Deepak Anant Hedge , Varsha Shashank Choudhary , Venkatasubramanian Radhakrjshnan Tarur , Dhananjay Govind Sathe , Harish Kashinath Mondkar , Samadhan Daulat Patil , Sasikumar Mohan Thoovara , Yogesh Sharad Bhide
发明人： Deepak Anant Hedge , Varsha Shashank Choudhary , Venkatasubramanian Radhakrjshnan Tarur , Dhananjay Govind Sathe , Harish Kashinath Mondkar , Samadhan Daulat Patil , Sasikumar Mohan Thoovara , Yogesh Sharad Bhide
IPC分类号： A61K31/785 , C08G61/02 , A61P13/12 , A61K9/28
CPC分类号： A61K31/785 , A61K9/284 , A61K9/2846 , A61K9/2866 , C08F8/02 , C08F8/08 , C08F126/02
摘要： Disclosed herein is an improved process for preparation of Sevelamer hydrochloride having phosphate binding capacity of 4.7 to 6.4 mmol/g. Further, the invention discloses Sevelamer hydrochloride compositions and a novel process for preparation of said compositions comprising high shear non-aqueous granulation.
摘要翻译： 本文公开了一种改进的具有4.7至6.4mmol / g的磷酸盐结合能力的盐酸司维拉姆的制备方法。 此外，本发明公开了盐酸司维拉姆组合物和用于制备包含高剪切非水性造粒物的所述组合物的新方法。
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3.发明授权公开(公告)号：US08187634B2
公开(公告)日：2012-05-29
申请号：US12377129
申请日：2007-08-31
申请人： Deepak Anant Hegde , Varsha Shashank Choudhary , Venkatasubramanian Radhakrishnan Tarur , Dhananjay Govind Sathe , Harish Kashinath Mondkar , Samadhan Daulat Patil , Sasikumar Mohan Thoovara , Yogesh Sharad Bhide
发明人： Deepak Anant Hegde , Varsha Shashank Choudhary , Venkatasubramanian Radhakrishnan Tarur , Dhananjay Govind Sathe , Harish Kashinath Mondkar , Samadhan Daulat Patil , Sasikumar Mohan Thoovara , Yogesh Sharad Bhide
IPC分类号： A61K31/785 , A61K9/28 , A61P13/12 , C08G61/02
CPC分类号： A61K31/785 , A61K9/284 , A61K9/2846 , A61K9/2866 , C08F8/02 , C08F8/08 , C08F126/02
摘要： Disclosed herein is an improved process for preparation of Sevelamer hydrochloride having phosphate binding capacity of 4.7 to 6.4 mmol/g. Further, the invention discloses Sevelamer hydrochloride compositions and a novel process for preparation of said compositions comprising high shear non-aqueous granulation.
摘要翻译： 本文公开了一种改进的具有4.7至6.4mmol / g的磷酸盐结合能力的盐酸司维拉姆的制备方法。 此外，本发明公开了盐酸司维拉姆组合物和用于制备包含高剪切非水性造粒物的所述组合物的新方法。
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4.发明申请公开(公告)号：US20100092421A1
公开(公告)日：2010-04-15
申请号：US12620931
申请日：2009-11-18
申请人： Deepak Anant Hegde , Varsha Shashank Choudhary , Venkatasubramanian Radhakrishnan Tarur , Dhananjay Govind Sathe , Harish Kashinath Mondkar , Samadhan Daulat Patil , Sasikumar Mohan Thoovara , Yogesh Sharad Bhide
发明人： Deepak Anant Hegde , Varsha Shashank Choudhary , Venkatasubramanian Radhakrishnan Tarur , Dhananjay Govind Sathe , Harish Kashinath Mondkar , Samadhan Daulat Patil , Sasikumar Mohan Thoovara , Yogesh Sharad Bhide
IPC分类号： A61K31/785 , A61P13/12 , C08G61/02
CPC分类号： A61K31/785 , A61K9/284 , A61K9/2846 , A61K9/2866 , C08F8/02 , C08F8/08 , C08F126/02
摘要： Disclosed herein is an improved process for preparation of Sevelamer hydrochloride having phosphate binding capacity of 4.7 to 6.4 mmol/g. Further, the invention discloses Sevelamer hydrochloride compositions and a novel process for preparation of said compositions comprising high shear non-aqueous granulation.
摘要翻译： 本文公开了一种改进的具有4.7至6.4mmol / g的磷酸盐结合能力的盐酸司维拉姆的制备方法。 此外，本发明公开了盐酸司维拉姆组合物和用于制备包含高剪切非水性造粒物的所述组合物的新方法。
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公开(公告)号：US07964182B2
公开(公告)日：2011-06-21
申请号：US12957810
申请日：2010-12-01
IPC分类号： A61K31/77 , A61K31/765 , A61K9/50 , C08G79/02
CPC分类号： A61K9/284 , A61K9/1641 , A61K9/2045 , A61K9/2095 , A61K9/2846 , A61K9/2866 , A61K31/785 , C08F8/00 , C08F26/02
摘要： The present invention discloses pharmaceutical composition comprising phosphate binding polymers such as Sevelamer carbonate substantially free of monovalent anion other than bicarbonate anion. Particularly, monovalent anion content is less than about 0.05% (w/w). Disclosed are compositions comprising wet granulated Sevelamer carbonate free of added metal ions and/or added monovalent anion source.
摘要翻译： 本发明公开了包含磷酸盐结合聚合物如基本上不含碳酸氢根阴离子以外的一价阴离子的赛维拉姆碳酸酯的药物组合物。 特别地，一价阴离子含量小于约0.05％（w / w）。 公开了包含不含添加的金属离子和/或添加的一价阴离子源的湿法制粒的赛维米尔碳酸盐的组合物。
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公开(公告)号：US20110064820A1
公开(公告)日：2011-03-17
申请号：US12957810
申请日：2010-12-01
IPC分类号： A61K9/14 , A61K31/785 , A61P13/12 , C08G67/00
CPC分类号： A61K9/284 , A61K9/1641 , A61K9/2045 , A61K9/2095 , A61K9/2846 , A61K9/2866 , A61K31/785 , C08F8/00 , C08F26/02
摘要： The present invention discloses pharmaceutical composition comprising phosphate binding polymers such as Sevelamer carbonate substantially free of monovalent anion other than bicarbonate anion. Particularly, monovalent anion content is less than about 0.05% (w/w). Disclosed are compositions comprising wet granulated Sevelamer carbonate free of added metal ions and/or added monovalent anion source.
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7.发明授权公开(公告)号：US07846425B2
公开(公告)日：2010-12-07
申请号：US12620931
申请日：2009-11-18
IPC分类号： A61K31/785 , A61P13/12 , C08G61/02
CPC分类号： A61K31/785 , A61K9/284 , A61K9/2846 , A61K9/2866 , C08F8/02 , C08F8/08 , C08F126/02
摘要： Disclosed herein is an improved process for preparation of Sevelamer hydrochloride having phosphate binding capacity of 4.7 to 6.4 mmol/g. Further, the invention discloses Sevelamer hydrochloride compositions and a novel process for preparation of said compositions comprising high shear non-aqueous granulation.
摘要翻译： 本文公开了一种改进的具有4.7至6.4mmol / g的磷酸盐结合能力的盐酸司维拉姆的制备方法。 此外，本发明公开了盐酸司维拉姆组合物和用于制备包含高剪切非水性造粒物的所述组合物的新方法。
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