公开(公告)号：US07682318B2

公开(公告)日：2010-03-23

申请号：US10363508

申请日：2002-06-12

申请人： Don Alden ,  Dominique M. Freeman ,  Paul Lum ,  Vladimir Drbal ,  Catherine K. Templin ,  Dirk Boecker

发明人： Don Alden ,  Dominique M. Freeman ,  Paul Lum ,  Vladimir Drbal ,  Catherine K. Templin ,  Dirk Boecker

IPC分类号： A61B5/00

CPC分类号： A61B5/15186 ,  A61B5/150022 ,  A61B5/150099 ,  A61B5/150152 ,  A61B5/150167 ,  A61B5/15019 ,  A61B5/150213 ,  A61B5/150221 ,  A61B5/150229 ,  A61B5/150412 ,  A61B5/150435 ,  A61B5/150503 ,  A61B5/150572 ,  A61B5/150916 ,  A61B5/15111 ,  A61B5/15117 ,  A61B5/15146 ,  A61B5/15151 ,  A61B5/15174

摘要： Blood samples can be collected without substantial contamination from ambient air, such that the blood sample may be analyzed accurately for gaseous components such as oxygen and carbon dioxide. An embodiment of the device has integrated actuation, lancing, and sample acquisition components, which in some embodiments are miniaturized and/or disposable.

摘要翻译： 可以收集血液样本而没有来自环境空气的实质污染，使得可以准确地分析血液样品用于气体组分如氧气和二氧化碳。 该装置的一个实施例具有集成的致动，采血和采样部件，其在一些实施例中是小型化和/或一次性的。

公开(公告)号：US07056475B2

公开(公告)日：2006-06-06

申请号：US10058797

申请日：2002-01-30

申请人： Paul Lum ,  Ganapati R. Mauze ,  Catherine K. Templin

发明人： Paul Lum ,  Ganapati R. Mauze ,  Catherine K. Templin

IPC分类号： G01N33/00

CPC分类号： B01L3/50273 ,  B01L2300/0816 ,  B01L2400/0481 ,  B01L2400/0633 ,  F04B43/043 ,  F04B43/082 ,  F04B43/1223 ,  G01N1/38 ,  Y10T436/2575

摘要： An apparatus and method for pumping and optionally mixing of small quantities of biological fluid wherein the pumping mechanism is segregated from the biological fluid being pumped. The micro-pump pushes the biological fluid by compressing a cartridge housing the blood and reagents with collapsible walls with a roller or ball bearing, synchronized perpendicular plungers, or an acutely-angled member to push the biological fluid by collapsing the walls of the cartridge in the direction of flow.

公开(公告)号：US5593564A

公开(公告)日：1997-01-14

申请号：US506233

申请日：1995-07-24

申请人： Catherine K. Templin ,  Douglass McManigill

发明人： Catherine K. Templin ,  Douglass McManigill

IPC分类号： G01N27/447 ,  C25B7/00 ,  G01N27/26

CPC分类号： G01N27/44743 ,  G01N27/44717

摘要： A flow gating interface system including a first microcolumnar section, a second microcolumnar section, and a channel for interfacing a first fluid conduit and a second fluid conduit is provided. The channel, having an inwardly facing wall, encloses at least a portion each of the first microcolumnar section and the second microcolumnar section for conducting a flush fluid flow past the outlet end of the first microcolumnar section and the inlet end of the second microcolumnar section. The inwardly facing wall of the channel nonfixedly constrains and aligns the end portions of the first and second microcolumnar sections. The outlet end of the first fluid conduit is connected to and in fluid communication with the first microcolumnar section of the flow gating interface. The inlet end of the second fluid conduit is connected to and in fluid communication with the second microcolumnar section of the flow gating interface.

摘要翻译： 提供了一种流动浇口界面系统，其包括第一微柱段，第二微柱段和用于与第一流体导管和第二流体导管连接的通道。 具有向内的壁的通道包围第一微柱段和第二微柱段中的每一个的至少一部分，用于使冲洗流体流经第一微柱段的出口端和第二微柱段的入口端。 通道的面向内的壁不固定地约束和对准第一和第二微柱段的端部。 第一流体导管的出口端与流动浇口界面的第一微柱部分连接并流体连通。 第二流体管道的入口端连接到流动浇口界面的第二微柱段并与其流体连通。