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公开(公告)号：US20080242759A1
公开(公告)日：2008-10-02
申请号：US12137206
申请日：2008-06-11
申请人： Dong Wu , Brant U. Kolb , Sumita B. Mitra , Bradley D. Craig , Brian N. Holmes , Richard P. Rusin , Mark S. Windisch
发明人： Dong Wu , Brant U. Kolb , Sumita B. Mitra , Bradley D. Craig , Brian N. Holmes , Richard P. Rusin , Mark S. Windisch
CPC分类号： A61K6/083 , A61K6/0017 , A61K6/0023 , A61K6/0088 , A61K6/087 , C08L33/04 , C08L63/00 , C08L33/00
摘要： The present invention provides a dental paste, a dental article, methods of making and using the dental paste, and compositions prepared therefrom. In one embodiment, the dental paste includes (a) a filler including porous, non-pyrogenic silica having a silane treated surface and being substantially free of heavy metals and (b) a filler including non-aggregated primary silica particles, with the fillers being dispersed in a hardenable resin.
摘要翻译： 本发明提供牙膏，牙科用品，牙膏的制造和使用方法以及由其制备的组合物。 在一个实施方案中，牙膏包括（a）填料，其包括具有硅烷处理表面并且基本上不含重金属的多孔非热解二氧化硅，和（b）包含非聚集的一次二氧化硅颗粒的填料，其中填料为 分散在可硬化的树脂中。
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公开(公告)号：US07393882B2
公开(公告)日：2008-07-01
申请号：US10353505
申请日：2003-01-29
申请人： Dong Wu , Brant U. Kolb , Sumita B. Mitra , Bradley D. Craig , Brian N. Holmes , Richard P. Rusin , Mark S. Windisch
发明人： Dong Wu , Brant U. Kolb , Sumita B. Mitra , Bradley D. Craig , Brian N. Holmes , Richard P. Rusin , Mark S. Windisch
CPC分类号： A61K6/083 , A61K6/0017 , A61K6/0023 , A61K6/0088 , A61K6/087 , C08L33/04 , C08L63/00 , C08L33/00
摘要： The present invention provides a dental paste, a dental article, methods of making and using the dental paste, and compositions prepared therefrom. In one embodiment, the dental paste includes (a) a filler including porous, non-pyrogenic silica having a silane treated surface and being substantially free of heavy metals and (b) a filler including non-aggregated primary silica particles, with the fillers being dispersed in a hardenable resin.
摘要翻译： 本发明提供牙膏，牙科用品，牙膏的制造和使用方法以及由其制备的组合物。 在一个实施方案中，牙膏包括（a）填料，其包括具有硅烷处理表面并且基本上不含重金属的多孔非热解二氧化硅，和（b）包含非聚集的一次二氧化硅颗粒的填料，其中填料为 分散在可硬化的树脂中。
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3.发明授权Radiopaque cationically polymerizable compositions comprising a radiopacifying filler, and method for polymerizing same 有权包含放射性填料的不透射线的阳离子聚合性组合物及其聚合方法公开(公告)号：US06306926B1
公开(公告)日：2001-10-23
申请号：US09168051
申请日：1998-10-07
申请人： Kathyrn R. Bretscher , Richard P. Rusin , Bradley D. Craig , Sumita B. Mitra , Joel D. Oxman , Janis R. Gust , Cheryl A. Hayne , James W. Westberg , Matthew C. Trom , Brant U. Kolb , Dwight W. Jacobs , David A. Kaisaki , James A. Baker
发明人： Kathyrn R. Bretscher , Richard P. Rusin , Bradley D. Craig , Sumita B. Mitra , Joel D. Oxman , Janis R. Gust , Cheryl A. Hayne , James W. Westberg , Matthew C. Trom , Brant U. Kolb , Dwight W. Jacobs , David A. Kaisaki , James A. Baker
IPC分类号： A61K6087
CPC分类号： A61K6/083 , A61K6/0073 , A61K6/087 , C01P2006/12 , C08K3/013 , C09C1/00 , C09C1/3045 , C09C1/40 , Y10S522/908 , Y10T428/2993 , C08L33/00 , C08L63/00
摘要： Polymerizable compositions that include: (a) a cationically active functional group; (b) an initiation system capable of initiating cationic polymerization of the cationically active functional group; and (c) a filler composition that includes various radiopacifying fillers in an amount sufficient to render the polymerizable composition radiopaque. Components (a), (b), and (c) are selected such that the polymerizable composition polymerizes to form a polymerized composition having a Barcol hardness, measured using a GYZJ-935 meter, of at least 10 within 30 minutes following initiation of the cationically active functional group at a reaction temperature of 25° C.
摘要翻译： 可聚合组合物，其包括：（a）阳离子活性官能团; （b）能够引发阳离子活性官能团的阳离子聚合的引发体系; 和（c）包含足以使可聚合组合物不透射线的量的各种放射性填料的填料组合物。 选择组分（a），（b）和（c），使得可聚合组合物聚合以形成具有Barcol硬度的聚合组合物，其在使用GYZJ-935米测量时在30分钟内至少10分钟 阳离子活性官能团的反应温度为25℃
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公开(公告)号：US06572693B1
公开(公告)日：2003-06-03
申请号：US09698986
申请日：2000-10-27
申请人： Dong Wu , Brian N. Holmes , Brant U. Kolb , Sumita B. Mitra , Wendy L. Thompson
发明人： Dong Wu , Brian N. Holmes , Brant U. Kolb , Sumita B. Mitra , Wendy L. Thompson
IPC分类号： A61K700
CPC分类号： B82Y30/00 , A61K6/0017 , A61K6/0023 , A61K6/007 , A61K6/083 , A61K6/087 , B01J13/0008 , C01G25/02 , C01P2004/62 , C01P2004/64 , C08K3/22 , C08K2003/2244 , C08K2201/011 , C08K2201/014 , C08L33/00 , C08L63/00
摘要： The invention provides for a material comprising(a) a hardenable resin; and (b) a filler comprising (i) clusters of nano-sized particles, the clusters comprising non-beavy metal oxide particles and heavy metal oxides, and being not fully densified particles and (ii) non-agglomerated nano-sized particles selected from the group consisting of non-heavy metal oxide particles, heavy metal oxide particles, and combinations thereof. The material is suitable for use as dental materials.
摘要翻译： 本发明提供了包含（a）可硬化树脂的材料; 和（b）填料，其包含（i）纳米尺寸颗粒簇，所述簇包含非金属氧化物颗粒和重金属氧化物，并且不是完全致密化的颗粒，和（ii）非聚集的纳米尺寸颗粒， 由非重金属氧化物颗粒，重金属氧化物颗粒及其组合组成的组。 该材料适用于牙科材料。
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公开(公告)号：US07030049B2
公开(公告)日：2006-04-18
申请号：US10269131
申请日：2002-10-11
申请人： Richard P. Rusin , Bradley D. Craig , Joel D. Oxman , James W. Westberg , Matthew C. Trom , Brant U. Kolb , James A. Baker
发明人： Richard P. Rusin , Bradley D. Craig , Joel D. Oxman , James W. Westberg , Matthew C. Trom , Brant U. Kolb , James A. Baker
IPC分类号： C04B35/14
CPC分类号： A61K6/083 , A61K6/0073 , A61K6/087 , C01P2006/12 , C08K3/013 , C09C1/00 , C09C1/3045 , C09C1/40 , Y10S522/908 , Y10T428/2993 , C08L33/00 , C08L63/00
摘要： Polymerizable compositions that include: (a) a cationically active functional group; (b) an initiation system capable of initiating cationic polymerization of the cationically active functional group; and (c) a filler composition that includes various radiopacifying fillers in an amount sufficient to render the polymerizable composition radiopaque. Components (a), (b), and (c) are selected such that the polymerizable composition polymerizes to form a polymerized composition having a Barcol hardness, measured using a GYZJ-935 meter, of at least 10 within 30 minutes following initiation of the cationically active functional group at a reaction temperature of 25° C.
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公开(公告)号：US07649029B2
公开(公告)日：2010-01-19
申请号：US10847782
申请日：2004-05-17
申请人： Brant U. Kolb , Hoa T. Bui , Jason P. Thalacker , Lani S. Kangas , Joel D. Oxman , Kenton D. Budd , Jacqueline C. Rolf , Sumita B. Mitra
发明人： Brant U. Kolb , Hoa T. Bui , Jason P. Thalacker , Lani S. Kangas , Joel D. Oxman , Kenton D. Budd , Jacqueline C. Rolf , Sumita B. Mitra
CPC分类号： A61K6/0023 , A61K6/0017 , A61K6/0835 , Y10S977/919 , C08L33/00
摘要： The present invention features ionomer compositions containing nanozirconia fillers. The compositions can be used in a variety of dental and orthodontic applications, for example, as adhesives, cements, restoratives, coatings and sealants.
摘要翻译： 本发明的特征在于含有纳米氧化锆填料的离聚物组合物。 组合物可用于各种牙科和正畸应用，例如粘合剂，水泥，修复剂，涂料和密封剂。
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公开(公告)号：US07091259B2
公开(公告)日：2006-08-15
申请号：US10190321
申请日：2002-07-03
申请人： Hoa T. Bui , Brant U. Kolb , Sumita B. Mitra
发明人： Hoa T. Bui , Brant U. Kolb , Sumita B. Mitra
CPC分类号： A61K6/083 , A61K6/0017 , A61K6/0023 , A61K6/0091 , A61K6/087 , Y10T428/2995 , C08L33/04 , C08L63/00
摘要： The present invention provides a dental paste, methods of making and using the dental paste, and compositions prepared therefrom. The dental paste includes (a) a filler including porous, non-pyrogenic silica having a silane treated surface and being substantially free of heavy metals and (b) a filler including non-agregated primary silica particles, with the fillers being dispersed in a hardenable resin. Fillers including porous, non-pyrogenic silica, and methods of making and using the fillers, are also provided.
摘要翻译： 本发明提供牙膏，制造和使用牙膏的方法以及由其制备的组合物。 牙膏包括可硬化树脂和设置在树脂中的酸反应性填料。 酸反应性填料包括硅烷处理的表面，其中硅烷包括含聚氧化烯烃基的硅烷。
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公开(公告)号：US07090722B2
公开(公告)日：2006-08-15
申请号：US10847805
申请日：2004-05-17
CPC分类号： A61K6/0835 , A61K6/0017 , A61K6/0023 , A61K6/087 , A61K6/09 , C08L33/00 , C08L75/04 , C08L63/00
摘要： Acid-reactive dental fillers, and methods of making and using such fillers, are disclosed. The acid-reactive dental fillers include a trivalent metal, oxygen, fluorine, an alkaline earth metal, and, optionally, silicon. The acid-reactive dental fillers are preferably nanostructured, for example, in the form of nanoparticles.
摘要翻译： 公开了酸反应性牙科填料，以及制备和使用这种填料的方法。 酸反应性牙科填料包括三价金属，氧，氟，碱土金属和任选的硅。 酸反应性牙科填料优选是纳米结构的，例如纳米颗粒的形式。
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9.发明授权公开(公告)号：US06613812B2
公开(公告)日：2003-09-02
申请号：US09753945
申请日：2001-01-03
申请人： Hoa T. Bui , Brant U. Kolb , Sumita B. Mitra
发明人： Hoa T. Bui , Brant U. Kolb , Sumita B. Mitra
IPC分类号： A61K6083
CPC分类号： A61K6/0017 , A61K6/0023 , A61K6/0038 , A61K6/0835 , C08L43/00 , C08L33/00
摘要： A dental composition is provided comprising (a) a part A comprising fluoroaluminosilicate glass that has been surface treated with agents selected from the group consisting of silane, silanol and combinations thereof, and at least one fatty acid, dimer thereof, or trimer thereof; and (b) a part B comprising at least one polyacid. The composition further comprises resin that can be curable or non-curable and at least one initiator. The composition exhibits adhesion to dentin, and the treated FAS glass contained therein does not settle out with time.
摘要翻译： 提供了一种牙科用组合物，其包含（a）包含氟铝硅酸盐玻璃的部分A，其已经用选自硅烷，硅烷醇及其组合的物质以及至少一种脂肪酸，二聚体或其三聚体进行表面处理; 和（b）包含至少一种多酸的部分B. 组合物还包含可固化或不可固化的树脂和至少一种引发剂。 该组合物表现出对牙本质的粘附性，并且其中所含的经处理的FAS玻璃不随时间而沉降。
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10.发明授权公开(公告)号：US07090721B2
公开(公告)日：2006-08-15
申请号：US10847803
申请日：2004-05-17
IPC分类号： A61K62/06
CPC分类号： A61K6/0017 , A61K6/0023 , A61K6/0835 , C08L33/00
摘要： The present invention features ionomer compositions containing nanofillers that provide the composition with desirable aesthetic properties (e.g., optical translucency). The compositions can be used in a variety of dental and orthodontic applications, for example, as adhesives, cements, restoratives, coatings and sealants.
摘要翻译： 本发明的特征在于含有纳米填料的离聚物组合物，其提供具有期望的美学特性（例如光学半透明性）的组合物。 组合物可用于各种牙科和正畸应用，例如粘合剂，水泥，修复剂，涂料和密封剂。
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