Optical monitoring of cleaving enzyme activity
    5.
    发明授权
    Optical monitoring of cleaving enzyme activity 失效
    光学监测切割酶活性

    公开(公告)号:US07521188B2

    公开(公告)日:2009-04-21

    申请号:US11070568

    申请日:2005-03-02

    IPC分类号: C12Q1/68 C07H21/04 C07K14/47

    摘要: A marker molecule for monitoring cleaving enzyme activity is disclosed. The marker molecule includes a protein, a peptide, or an oligonucleotide. A co-factor is conjugated to the protein, the peptide, or the oligonucleotide, thereby forming a co-factor labeled protein, a co-factor labeled peptide, or a co-factor labeled oligonucleotide. The co-factor is adapted to produce an enzymatic signal that is optically detectable.

    摘要翻译: 公开了一种用于监测切割酶活性的标记分子。 标记分子包括蛋白质,肽或寡核苷酸。 辅因子与蛋白质,肽或寡核苷酸结合,从而形成辅因子标记的蛋白质,辅因子标记肽或辅因子标记的寡核苷酸。 辅因子适于产生可光学检测的酶信号。