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    FILM COMPOSITION FOR HARD CAPSULE SHELLS
    1.
    发明申请
    FILM COMPOSITION FOR HARD CAPSULE SHELLS 审中-公开
    硬胶囊的胶片组合物

    公开(公告)号：US20150150817A1

    公开(公告)日：2015-06-04

    申请号：US14415614

    申请日：2013-07-12

    Applicant: Dow Global Technologies LLC

    Inventor： Bettina Hoelzer

    IPC: A61K9/48 ,  A61K47/38 ,  A61K47/18 ,  C08J5/18

    CPC classification number: A61K9/4816 ,  A61K47/18 ,  A61K47/38 ,  C08J5/18 ,  C08J2301/28

    Abstract: A film-forming composition comprising (a) a cellulose derivative such as HPMC and (b) a urea additive selected from urea, urea derivatives and mixtures thereof; the use of the film-forming composition as a shell material for hard capsules; and films and hard capsules prepared from the film-forming composition.

    Abstract translation: 一种成膜组合物，其包含（a）纤维素衍生物如HPMC和（b）选自脲，脲衍生物及其混合物的脲添加剂; 使用成膜组合物作为硬胶囊的壳材料; 以及由成膜组合物制备的薄膜和硬胶囊。

    PROCESS FOR PRODUCING CELLULOSE DERIVATIVES OF HIGH BULK DENSITY, GOOD FLOWABILITY AND/OR DISPERSIBILITY IN COLD WATER AS WELL AS LOW SOLUTION COLOR
    3.
    发明申请
    PROCESS FOR PRODUCING CELLULOSE DERIVATIVES OF HIGH BULK DENSITY, GOOD FLOWABILITY AND/OR DISPERSIBILITY IN COLD WATER AS WELL AS LOW SOLUTION COLOR 有权
    用于生产高密度密度的纤维素衍生物的方法，冷水中良好的流动性和/或分散性，以及作为低溶液颜色

    公开(公告)号：US20150239992A1

    公开(公告)日：2015-08-27

    申请号：US14422253

    申请日：2013-09-23

    Applicant: Dow Global Technologies LLC

    Inventor： Yvonne M. Goerlach-Doht ,  Juergen Hermanns ,  Bettina Hoelzer

    IPC: C08B11/193 ,  A61K47/38 ,  A61K9/48

    CPC classification number: C08B11/193 ,  A61K9/4891 ,  A61K47/38 ,  C08J3/124 ,  C08J2301/08 ,  C08L1/08 ,  C08L1/26 ,  C08L1/28 ,  C08L1/284 ,  C09D101/08 ,  C09D101/26 ,  Y10T428/2982

    Abstract: A particulate cellulose derivative is obtained in a process of grinding and drying a moist cellulose derivative which comprises the steps of A) providing a cellulose derivative having a moisture content of from 60 to 95 percent, based on the total weight of the moist cellulose derivative; B) grinding and partially drying the moist cellulose derivative in a gas-swept impact mill; C) contacting the ground and partially dried cellulose derivative with an additional amount of a drying gas outside the gas-swept impact mill; and D) subjecting the cellulose derivative to partial depolymerization after having contacted the cellulose derivative with a drying gas in step C). The obtained particulate cellulose derivative has a high untapped bulk density, a good flowability and a low color intensity.

    Abstract translation: 在研磨和干燥湿纤维素衍生物的方法中获得颗粒状纤维素衍生物，其包括以下步骤：A）提供基于湿纤维素衍生物的总重量的水分含量为60至95％的纤维素衍生物; B）在气体扫掠冲击式研磨机中研磨和部分干燥湿纤维素衍生物; C）将接地和部分干燥的纤维素衍生物与气体扫掠冲击式磨机外部的附加量的干燥气体接触; 和D）在步骤C）中使纤维素衍生物与干燥气体接触后使纤维素衍生物部分解聚。 所获得的颗粒状纤维素衍生物具有高的未开发堆积密度，良好的流动性和低的颜色强度。

    PROCESS FOR PREPRING A MIXTURE OF A CELLULOSE DERIVATIVE AND A LIQUID DILUENT
    4.
    发明申请
    PROCESS FOR PREPRING A MIXTURE OF A CELLULOSE DERIVATIVE AND A LIQUID DILUENT 审中-公开
    用于制备纤维素衍生物和液体稀释剂的混合物的方法

    公开(公告)号：US20160289393A1

    公开(公告)日：2016-10-06

    申请号：US15036912

    申请日：2014-12-01

    Applicant: DOW GLOBAL TECHNOLOGIES LLC

    Inventor： Bettina Hoelzer ,  Alexandra Hild ,  Juergen Hermanns ,  Jorg Theuerkauf

    IPC: C08J3/03 ,  B01J13/04 ,  C09D101/28 ,  C08L1/28

    CPC classification number: C08J3/03 ,  B01J13/04 ,  C08J2301/28 ,  C08L1/08 ,  C08L1/284 ,  C09D101/08 ,  C09D101/284

    Abstract: A mixture of a cellulose derivative and a liquid diluent is prepared which comprises at least 5 weight percent of the cellulose derivative, based on the total weight of the cellulose derivative and the liquid diluent. The mixing operating causes air to be entrapped in the mixture. The time for at least partially removing entrapped air is reduced by providing a cellulose derivative having a specific surface area of less than 0.20 m2/g measured by BET method for preparing the mixture.

    Abstract translation: 制备纤维素衍生物和液体稀释剂的混合物，其包含至少5重量％的纤维素衍生物，基于纤维素衍生物和液体稀释剂的总重量。 混合操作会使空气被捕获在混合物中。 通过提供通过BET法测量的比表面积小于0.20m 2 / g的纤维素衍生物来制备混合物来减少至少部分去除夹带空气的时间。

    PROCESS FOR PRODUCING CELLULOSE DERIVATIVES OF HIGH BULK DENSITY, GOOD FLOWABILITY AND/OR DISPERSIBILITY IN COLD WATER AS WELL AS LOW SOLUTION COLOR
    5.
    发明申请
    PROCESS FOR PRODUCING CELLULOSE DERIVATIVES OF HIGH BULK DENSITY, GOOD FLOWABILITY AND/OR DISPERSIBILITY IN COLD WATER AS WELL AS LOW SOLUTION COLOR 审中-公开
    用于生产高密度密度的纤维素衍生物的方法，冷水中良好的流动性和/或分散性，以及作为低溶液颜色

    公开(公告)号：US20160244533A1

    公开(公告)日：2016-08-25

    申请号：US15096704

    申请日：2016-05-04

    Applicant: Dow Global Technologies LLC

    Inventor： Yvonne M. Goerlach-Doht ,  Juergen Hermanns ,  Bettina Hoelzer

    IPC: C08B11/193 ,  C09D101/26

    CPC classification number: C08B11/193 ,  A61K9/4891 ,  A61K47/38 ,  C08J3/124 ,  C08J2301/08 ,  C08L1/08 ,  C08L1/26 ,  C08L1/28 ,  C08L1/284 ,  C09D101/08 ,  C09D101/26 ,  Y10T428/2982

    Abstract: A particulate cellulose derivative is obtained in a process of grinding and drying a moist cellulose derivative which comprises the steps of A) providing a cellulose derivative having a moisture content of from 60 to 95 percent, based on the total weight of the moist cellulose derivative, B) grinding and partially drying the moist cellulose derivative in a gas-swept impact mill; C) contacting the ground and partially dried cellulose derivative with an additional amount of a drying gas outside the gas-swept impact mill; and D) subjecting the cellulose derivative to partial depolymerization after having contacted the cellulose derivative with a drying gas in step C). The obtained particulate cellulose derivative has a high untapped bulk density, a good flowability and a low color intensity.

    Abstract translation: 在研磨和干燥湿纤维素衍生物的方法中获得颗粒状纤维素衍生物，其包括以下步骤：A）提供基于湿纤维素衍生物的总重量的水分含量为60至95％的纤维素衍生物， B）在气体扫掠冲击式研磨机中研磨和部分干燥湿纤维素衍生物; C）将接地和部分干燥的纤维素衍生物与气体扫掠冲击式磨机外部的附加量的干燥气体接触; 和D）在步骤C）中使纤维素衍生物与干燥气体接触后使纤维素衍生物部分解聚。 所获得的颗粒状纤维素衍生物具有高的未开发堆积密度，良好的流动性和低的颜色强度。

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