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公开(公告)号：US20220119830A1
公开(公告)日：2022-04-21
申请号：US17645631
申请日：2021-12-22
发明人： SCOTT DIEHN , AJIT NOTT , DAVID SELINGER , CARL SIMMONS , PRIYANKA BHYRI , VENKATA S TAVVA
IPC分类号： C12N15/82
摘要： The invention relates to gene expression regulatory sequences, specifically introns that act as enhancers of gene expression, the promoter and terminator sequences endogenously associated with these introns. Presence of these intronic enhancer sequences in proximity to promoter sequences leads to enhancement of gene expression. Methods of finding such new intronic enhancer sequences and using them to generate transgenic plants are also described.
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公开(公告)号：US20190316142A1
公开(公告)日：2019-10-17
申请号：US16429846
申请日：2019-06-03
发明人： SCOTT DIEHN , AJIT NOTT , DAVID A SELINGER , CARL SIMMONS , PRIYANKA BHYRI , VENKATA S TAVVA
IPC分类号： C12N15/82
摘要： The invention relates to gene expression regulatory sequences, specifically introns that act as enhancers of gene expression, the promoter and terminator sequences endogenously associated with these introns. Presence of these intronic enhancer sequences in proximity to promoter sequences leads to enhancement of gene expression. Methods of finding such new intronic enhancer sequences and using them to generate transgenic plants are also described.
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公开(公告)号：US20150184177A1
公开(公告)日：2015-07-02
申请号：US14660076
申请日：2015-03-17
发明人： SCOTT DIEHN , AJIT NOTT , DAVID A SELINGER , CARL SIMMONS , PRIYANKA BHYRI , VENKATA S TAVVA
IPC分类号： C12N15/82 , G01N33/573 , C12Q1/68
CPC分类号： C12N15/8216
摘要： The invention relates to gene expression regulatory sequences, specifically introns that act as enhancers of gene expression, the promoter and terminator sequences endogenously associated with these introns. Presence of these intronic enhancer sequences in proximity to promoter sequences leads to enhancement of gene expression. Methods of finding such new intronic enhancer sequences and using them to generate transgenic plants are also described.
摘要翻译： 本发明涉及基因表达调控序列，特别是作为基因表达增强子的内含子，与这些内含子内源性相关的启动子和终止子序列。 这些内含子增强子序列在启动子序列附近的存在导致基因表达的增强。 还描述了发现这种新的内含子增强子序列并将其用于产生转基因植物的方法。
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公开(公告)号：US20170335337A1
公开(公告)日：2017-11-23
申请号：US15660390
申请日：2017-07-26
发明人： SCOTT DIEHN , AJIT NOTT , DAVID A. SELINGER , CARL SIMMONS , PRIYANKA BHYRI , VENKATA S. TAVVA
IPC分类号： C12N15/82 , C12Q1/68 , G01N33/573
CPC分类号： C12N15/8216
摘要： The invention relates to gene expression regulatory sequences, specifically introns that act as enhancers of gene expression, the promoter and terminator sequences endogenously associated with these introns. Presence of these intronic enhancer sequences in proximity to promoter sequences leads to enhancement of gene expression. Methods of finding such new intronic enhancer sequences and using them to generate transgenic plants are also described.
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公开(公告)号：US20240279672A1
公开(公告)日：2024-08-22
申请号：US18641717
申请日：2024-04-22
发明人： CARL SIMMONS
IPC分类号： C12N15/82
CPC分类号： C12N15/8261 , C12N15/8205 , C12N15/8207
摘要： Provided are compositions comprising polynucleotides and polypeptides for the improvement of agronomic traits in plants, in particular maize plants. Also provided are recombinant DNA constructs, plants, plant cells, seed, grain comprising the polynucleotides and/or polypeptides. Additionally, various methods of employing the polynucleotides and genetic modifications in plants, such as methods for increasing yield of a plant are also provided herein.
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公开(公告)号：US20180105824A1
公开(公告)日：2018-04-19
申请号：US15561388
申请日：2016-03-22
发明人： CARL SIMMONS , SOBHANA SIVASANKAR
IPC分类号： C12N15/82 , C07K14/415
CPC分类号： C12N15/8217 , C07K14/415 , C12N15/8261 , C12N15/8273 , C12N15/8279 , Y02A40/146
摘要： Nucleotide sequences encoding DREB2 polypeptides are provided herein, along with plants and cells having increased levels of DREB2 gene expression, increased levels of DREB2 transcription factor activity, or both. Plants with increased levels of at least one DREB2 gene expression that exhibit increased yield, increased abiotic stress tolerance, or any combination of these, are provided. Methods for increasing yield, and abiotic stress tolerance in plants, by modulating DREB2 gene expression or activity, are also provided.
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公开(公告)号：US20210155951A1
公开(公告)日：2021-05-27
申请号：US17047518
申请日：2019-04-17
发明人： CARLOS M LA ROTA , ROSANA MELO , BO SHEN , CARL SIMMONS , JINGRUI WU
IPC分类号： C12N15/82
摘要： Provided are compositions comprising polynucleotides encoding polypeptides. Also provided are recombinant DNA constructs, plants, plant cells, seed, grain comprising the polynucleotides, and plants, plant cells, seed, grain comprising a genetic modification at a genomic locus encoding a polypeptide. Additionally, various methods of employing the polynucleotides and genetic modifications in plants, such as methods for modulating expression level in a plant and methods for increasing yield of a plant are also provided herein.
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公开(公告)号：US20230212599A1
公开(公告)日：2023-07-06
申请号：US17647183
申请日：2022-01-06
发明人： CARL SIMMONS
IPC分类号： C12N15/82
CPC分类号： C12N15/8261 , C12N15/8207 , C12N15/8205
摘要： Provided are compositions comprising polynucleotides and polypeptides for the improvement of agronomic traits in plants, in particular maize plants. Also provided are recombinant DNA constructs, plants, plant cells, seed, grain comprising the polynucleotides and/or polypeptides. Additionally, various methods of employing the polynucleotides and genetic modifications in plants, such as methods for increasing yield of a plant are also provided herein.
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9.发明申请公开(公告)号：US20160017349A1
公开(公告)日：2016-01-21
申请号：US14772816
申请日：2014-03-13
发明人： Mule Ayele , KEVIN HAYES , CARL SIMMONS , SOBHANA SIVASANKAR , JOHN VAN HEMERT , BING-BING WANG
IPC分类号： C12N15/82
CPC分类号： C12N15/8218 , C12N15/8261 , C12N15/8273 , Y02A40/146
摘要： Methods and compositions for maize target gene suppression and improving an agronomic trait through microRNAs or target gene modulation are disclosed. Polynucleotide constructs useful for gene silencing, or upregulation or modulation as well as cells, plants and seeds comprising the polynucleotides and methods for using microRNAs to silence a target gene are also described.
摘要翻译： 公开了用于玉米靶基因抑制和通过微小RNA或靶基因调节改善农艺性状的方法和组合物。 还描述了可用于基因沉默或上调或调节的多核苷酸构建体以及包含多核苷酸的细胞，植物和种子以及使用微小RNA沉默靶基因的方法。
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10.发明申请GENES FOR IMPROVING NUTRIENT UPTAKE AND ABIOTIC STRESS TOLERANCE IN PLANTS 审中-公开改善植物营养摄取和生物胁迫耐受性的基因公开(公告)号：US20160002648A1
公开(公告)日：2016-01-07
申请号：US14771528
申请日：2014-03-03
申请人： Mei GUO , Kevin R. HAYES , Brooke PETERSON-BURCH , Carl R. SIMMONS , Shoba SIVASANKAR , Jijun ZOU , PIONEER HI-BRED INTERNATIONAL INC.
发明人： MEI GUO , KEVIN HAYES , BROOKE PETERSON-BURCH , CARL SIMMONS , SOBHANA SIVASANKAR , JIJUN ZOU
IPC分类号： C12N15/82 , C12N9/12 , C12Q1/68 , C07K14/415
CPC分类号： C12N15/8243 , C07K14/415 , C12N9/12 , C12N15/8218 , C12N15/8261 , C12N15/8273 , C12N15/8274 , C12N15/8286 , C12Q1/6895 , C12Q2600/13 , C12Q2600/156 , C12Y207/11025 , Y02A40/146
摘要： The present disclosure provides methods to increase crop yield utilizing transgenic genes controlling plant growth and yield. The specific genes can be used to increase tissue growth and abiotic stress tolerance. Plants, plant progeny, seeds and tissues created by these methods are also described. Polynucleotides encoding the sequences are provided for expression in a plant of interest. Expression cassettes, plants, plant cells, plant parts and seeds comprising the sequences of the disclosure are further provided. In specific embodiments, the polynucleotide is operably linked to a constitutive promoter.
摘要翻译： 本公开提供了利用控制植物生长和产量的转基因基因提高作物产量的方法。 具体的基因可用于增加组织生长和非生物胁迫耐受性。 还描述了通过这些方法产生的植物，植物后代，种子和组织。 提供编码序列的多核苷酸用于在感兴趣的植物中表达。 还提供了包含本公开的序列的表达盒，植物，植物细胞，植物部分和种子。 在具体实施方案中，多核苷酸可操作地连接于组成型启动子。
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