公开(公告)号：US20210275303A1

公开(公告)日：2021-09-09

申请号：US17327575

申请日：2021-05-21

Applicant: Edwards Lifesciences Corporation

Inventor： Evan T. Schwartz ,  Sean Chow ,  Sandip Vasant Pawar ,  Darshin S. Patel ,  Chambory Chhe ,  Arpit Laddha ,  Ngoc Huong Thi Nguyen ,  Waina Michelle Chu ,  Yuanlong Du ,  Michael Bukin ,  Boaz Manash ,  Sara Tzadok (formerly Haivatov) ,  Tamir S. Levi

IPC: A61F2/24

Abstract: A prosthetic heart valve includes a frame having an inflow end and an outflow end, and defining a longitudinal axis. The prosthetic heart valve further includes a leaflet structure situated at least partially within the frame, and a covering disposed around the frame. The covering includes a first woven portion extending circumferentially around the frame and including a plurality of texturized strands or yarns extending along the longitudinal axis of the frame. The covering further includes a second woven portion extending circumferentially around the frame and spaced apart from the first woven portion along the longitudinal axis of the frame. The texturized strands extend along the longitudinal axis of the frame from the first woven portion to the second woven portion and form a floating portion between the first woven portion and the second woven portion.

公开(公告)号：US20180133000A1

公开(公告)日：2018-05-17

申请号：US15809915

申请日：2017-11-10

Applicant: Edwards Lifesciences Corporation

Inventor： Taylor Jacob Scheinblum ,  Mindy Lee Ann Black ,  Tamir S. Levi ,  Evan T. Schwartz ,  Waina Michelle Chu ,  Linda Thai ,  Hanoch Cohen-Tzemach ,  Michael Bukin

IPC: A61F2/24

CPC classification number: A61F2/2412 ,  A61F2/2403 ,  A61F2/2415 ,  A61F2/2418 ,  A61F2/2427 ,  A61F2/2433 ,  A61F2/2454 ,  A61F2/95 ,  A61F2002/9522 ,  B25B27/02

Abstract: Embodiments are provided of an assembly having a prosthetic valve, the prosthetic valve having a radially expandable and compressible annular frame, and a crimping accessory device, and methods for using the assembly in compressing the prosthetic valve. The frame includes an outer surface and an inner surface. A leaflet assembly is supported inside the annular frame. The leaflet assembly includes a plurality of leaflets, each having an inner surface and an outer surface. The crimping accessory device has a plurality of axially-extending fingers. At least a first finger of the plurality of fingers is disposed between the outer surface of a first leaflet of the plurality of leaflets, and at least a second finger of the plurality of fingers is disposed radially-inwardly of the inner surface of the first leaflet.

公开(公告)号：US20230277312A1

公开(公告)日：2023-09-07

申请号：US18315500

申请日：2023-05-11

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Tram Ngoc Nguyen ,  Hannah Reed Bettencourt ,  Evan T. Schwartz

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/2466 ,  A61F2250/0069 ,  A61F2210/0014

Abstract: A sealing frame surrounds a radially-outer surface portion of a valve frame of a prosthetic heart valve. Both the valve frame and the sealing frame are radially collapsible and expandable between respective compressed and expanded configurations. The sealing frame has a first axial end coupled to the valve frame at its inflow end, and a second axial end coupled to the valve frame at a location between its inflow and outflow ends. The sealing frame also has an intermediate portion between the first and second axial ends that projects radially outward when the valve and sealing frames are in their expanded configurations. The sealing frame displaces an outer skirt of the prosthetic heart valve radially outward and urges the outer skirt into contact with surrounding native tissue, thereby reducing or avoiding paravalvular leakage. In some examples, the sealing frame can be formed of a shape memory material.

公开(公告)号：US11013600B2

公开(公告)日：2021-05-25

申请号：US16252890

申请日：2019-01-21

Applicant: Edwards Lifesciences Corporation

Inventor： Evan T. Schwartz ,  Sean Chow ,  Sandip Vasant Pawar ,  Darshin S. Patel ,  Chambory Chhe ,  Arpit Laddha ,  Ngoc Huong Thi Nguyen ,  Waina Michelle Chu ,  Yuanlong Du ,  Michael Bukin ,  Boaz Manash ,  Sara Haivatov ,  Tamir S. Levi

IPC: A61F2/24

Abstract: A prosthetic heart valve includes a frame having an inflow end and an outflow end, and defining a longitudinal axis. The prosthetic heart valve further includes a leaflet structure situated at least partially within the frame, and a covering disposed around the frame. The covering includes a first woven portion extending circumferentially around the frame and including a plurality of texturized strands or yarns extending along the longitudinal axis of the frame. The covering further includes a second woven portion extending circumferentially around the frame and spaced apart from the first woven portion along the longitudinal axis of the frame. The texturized strands extend along the longitudinal axis of the frame from the first woven portion to the second woven portion and form a floating portion between the first woven portion and the second woven portion.

公开(公告)号：US20240189098A1

公开(公告)日：2024-06-13

申请号：US18443128

申请日：2024-02-15

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Sara Tzadok ,  Khen Perlmutter ,  Darshin S. Patel ,  Boaz Manash ,  Ajay Chadha ,  Waina Michelle Chu ,  Chambory Chhe ,  Evan T. Schwartz ,  Sandip Vasant Pawar

IPC: A61F2/24 ,  A61F2/00

CPC classification number: A61F2/2412 ,  A61F2/0077 ,  A61F2/2409 ,  A61F2/2418 ,  A61F2002/0086 ,  A61F2/243 ,  A61F2210/0076

Abstract: A prosthetic heart valve has a frame including a plurality of strut members, the frame being radially expandable and collapsible between a collapsed state and an expanded state, the frame having an inflow end and an outflow end and defining a longitudinal axis. A leaflet structure is situated at least partially within the frame. A covering is disposed around an exterior of the frame and includes a cushioning layer, a first strip of material coupled to the cushioning layer and folded to encapsulate apices of the strut members of the inflow end of the frame, and a second strip of material coupled to the cushioning layer and folded to encapsulate apices of the strut members of the outflow end of the frame. The cushioning layer includes texturized filaments that provide compressible volume and a plush surface to the cushioning layer when the frame is in the expanded state.

公开(公告)号：US20230270540A1

公开(公告)日：2023-08-31

申请号：US18314759

申请日：2023-05-09

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Evan T. Schwartz ,  Darshin S. Patel ,  Jocelyn Chau ,  Hannah Reed Bettencourt

IPC: A61F2/24

CPC classification number: A61F2/2412 ,  A61F2/2409 ,  A61F2220/0075

Abstract: A prosthetic heart valve can have one or more hermetic layers. The inner skirt and/or the outer skirt can comprise one or more hermetic layers, or the entire valve frame can be encapsulated within one or more hermetic layers. Each hermetic layer can be substantially nonporous or can have pores therein that are sized to discourage cellular ingrowth. The hermetic layer can prevent ingrowth of surrounding native tissue, thereby reducing pannus formation on the prosthetic leaflets. Alternatively or additionally, shapes of the leaflets of the valvular structure of the prosthetic valve and/or the coupling of the leaflets to the valve frame can be selected to avoid the incidence of stasis when implanted at a relatively low pressure gradient hemodynamic location. Such a prosthetic heart valve may reduce the risk of thrombosis.

公开(公告)号：US10973631B2

公开(公告)日：2021-04-13

申请号：US15809915

申请日：2017-11-10

Applicant: Edwards Lifesciences Corporation

Inventor： Taylor Jacob Scheinblum ,  Mindy Lee Ann Black ,  Tamir S. Levi ,  Evan T. Schwartz ,  Waina Michelle Chu ,  Linda Thai ,  Hanoch Cohen-Tzemach ,  Michael Bukin

IPC: A61F2/24 ,  A61F2/95 ,  B25B27/02

Abstract: Embodiments are provided of an assembly having a prosthetic valve, the prosthetic valve having a radially expandable and compressible annular frame, and a crimping accessory device, and methods for using the assembly in compressing the prosthetic valve. The frame includes an outer surface and an inner surface. A leaflet assembly is supported inside the annular frame. The leaflet assembly includes a plurality of leaflets, each having an inner surface and an outer surface. The crimping accessory device has a plurality of axially-extending fingers. At least a first finger of the plurality of fingers is disposed between the outer surface of a first leaflet of the plurality of leaflets, and at least a second finger of the plurality of fingers is disposed radially-inwardly of the inner surface of the first leaflet.

公开(公告)号：US20250009499A1

公开(公告)日：2025-01-09

申请号：US18887376

申请日：2024-09-17

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Evan T. Schwartz

IPC: A61F2/24 ,  A61F2/00

Abstract: A packaging assembly for storing a prosthetic heart valve can comprise a valve tray comprising an annular rim and a cavity extending away from the annular rim, wherein the cavity is configured to accept the prosthetic heart valve. The packaging assembly can further comprise a lid configured to cover the annular rim. The packaging assembly can further comprise a leaflet biasing element disposed on a central portion of the lid. The leaflet biasing element can comprise an extrusion with a paraboloid shape that can extend from a lower surface of the lid towards the valve tray. The leaflet biasing element can be configured to extend at least partially into an inflow end portion of the prosthetic heart valve and secure a plurality of leaflets of the prosthetic heart valve in a desired configuration when the prosthetic heart valve is inserted in the cavity and the lid is closed over the annular rim.

公开(公告)号：US12138155B2

公开(公告)日：2024-11-12

申请号：US17228446

申请日：2021-04-12

Applicant: Edwards Lifesciences Corporation

Inventor： Taylor Jacob Scheinblum ,  Mindy Lee Ann Black ,  Tamir S. Levi ,  Evan T. Schwartz ,  Waina Michelle Chu ,  Linda Thai ,  Hanoch Cohen-Tzemach ,  Michael Bukin

IPC: A61F2/24 ,  A61F2/95 ,  B25B27/02

Abstract: Embodiments are provided of an assembly having a prosthetic valve, the prosthetic valve having a radially expandable and compressible annular frame, and a crimping accessory device, and methods for using the assembly in compressing the prosthetic valve. The frame includes an outer surface and an inner surface. A leaflet assembly is supported inside the annular frame. The leaflet assembly includes a plurality of leaflets, each having an inner surface and an outer surface. The crimping accessory device has a plurality of axially-extending fingers. At least a first finger of the plurality of fingers is disposed between the outer surface of a first leaflet of the plurality of leaflets, and at least a second finger of the plurality of fingers is disposed radially-inwardly of the inner surface of the first leaflet.

公开(公告)号：US20230255755A1

公开(公告)日：2023-08-17

申请号：US18308525

申请日：2023-04-27

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Evan T. Schwartz

IPC: A61F2/24

CPC classification number: A61F2/2409 ,  A61F2250/0063

Abstract: This disclosure is directed to a docking device for a prosthetic heart valve. The docking device includes an inflow end, an outflow end, a support structure disposed between the inflow end and the outflow end, and an expandable sleeve. The support structure includes inflow and outflow sections that are configured to be positioned on inflow and outflow sides, respectively, of a native heart valve. The outflow section includes a first portion, a second portion, and a third portion, wherein the first portion is disposed closer to the inflow section than the second portion, and wherein the third portion is disposed between the first and second portions. The expandable sleeve may extend at least 100 degrees over the first portion of the outflow section of the support structure. Additionally, or alternatively, the first portion of the outflow section of the support structure may have a different geometry than the third portion.