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公开(公告)号：US11013600B2
公开(公告)日：2021-05-25
申请号：US16252890
申请日：2019-01-21
发明人： Evan T. Schwartz , Sean Chow , Sandip Vasant Pawar , Darshin S. Patel , Chambory Chhe , Arpit Laddha , Ngoc Huong Thi Nguyen , Waina Michelle Chu , Yuanlong Du , Michael Bukin , Boaz Manash , Sara Haivatov , Tamir S. Levi
IPC分类号： A61F2/24
摘要： A prosthetic heart valve includes a frame having an inflow end and an outflow end, and defining a longitudinal axis. The prosthetic heart valve further includes a leaflet structure situated at least partially within the frame, and a covering disposed around the frame. The covering includes a first woven portion extending circumferentially around the frame and including a plurality of texturized strands or yarns extending along the longitudinal axis of the frame. The covering further includes a second woven portion extending circumferentially around the frame and spaced apart from the first woven portion along the longitudinal axis of the frame. The texturized strands extend along the longitudinal axis of the frame from the first woven portion to the second woven portion and form a floating portion between the first woven portion and the second woven portion.
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公开(公告)号：US20240033079A1
公开(公告)日：2024-02-01
申请号：US18482636
申请日：2023-10-06
发明人： Shahram Zamani , Waina Michelle Chu , Ziv Yohanan , Dikla Kersh
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2250/0018 , A61F2250/0037 , A61F2250/0036 , A61F2240/001
摘要： Disclosed herein are implantable medical devices comprising a textile material comprising a first material and a second material having different stretchability and flexibility, where the first and the second materials are at least partially superposed and coupled to each other. The medical devices of the current disclosure can be implantable prosthetic valves. The valves of the present disclosure provide for a reduced crimped profile and improve PVL sealing. In addition, disclosed herein are methods of making the implantable medical devices.
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公开(公告)号：US20210275303A1
公开(公告)日：2021-09-09
申请号：US17327575
申请日：2021-05-21
发明人： Evan T. Schwartz , Sean Chow , Sandip Vasant Pawar , Darshin S. Patel , Chambory Chhe , Arpit Laddha , Ngoc Huong Thi Nguyen , Waina Michelle Chu , Yuanlong Du , Michael Bukin , Boaz Manash , Sara Tzadok (formerly Haivatov) , Tamir S. Levi
IPC分类号： A61F2/24
摘要： A prosthetic heart valve includes a frame having an inflow end and an outflow end, and defining a longitudinal axis. The prosthetic heart valve further includes a leaflet structure situated at least partially within the frame, and a covering disposed around the frame. The covering includes a first woven portion extending circumferentially around the frame and including a plurality of texturized strands or yarns extending along the longitudinal axis of the frame. The covering further includes a second woven portion extending circumferentially around the frame and spaced apart from the first woven portion along the longitudinal axis of the frame. The texturized strands extend along the longitudinal axis of the frame from the first woven portion to the second woven portion and form a floating portion between the first woven portion and the second woven portion.
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公开(公告)号：US20180133000A1
公开(公告)日：2018-05-17
申请号：US15809915
申请日：2017-11-10
发明人： Taylor Jacob Scheinblum , Mindy Lee Ann Black , Tamir S. Levi , Evan T. Schwartz , Waina Michelle Chu , Linda Thai , Hanoch Cohen-Tzemach , Michael Bukin
IPC分类号： A61F2/24
CPC分类号： A61F2/2412 , A61F2/2403 , A61F2/2415 , A61F2/2418 , A61F2/2427 , A61F2/2433 , A61F2/2454 , A61F2/95 , A61F2002/9522 , B25B27/02
摘要： Embodiments are provided of an assembly having a prosthetic valve, the prosthetic valve having a radially expandable and compressible annular frame, and a crimping accessory device, and methods for using the assembly in compressing the prosthetic valve. The frame includes an outer surface and an inner surface. A leaflet assembly is supported inside the annular frame. The leaflet assembly includes a plurality of leaflets, each having an inner surface and an outer surface. The crimping accessory device has a plurality of axially-extending fingers. At least a first finger of the plurality of fingers is disposed between the outer surface of a first leaflet of the plurality of leaflets, and at least a second finger of the plurality of fingers is disposed radially-inwardly of the inner surface of the first leaflet.
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公开(公告)号：US11872125B2
公开(公告)日：2024-01-16
申请号：US17659577
申请日：2022-04-18
发明人： Nikolai Gurovich , Michael Bukin , Elena Sherman , Tamir S. Levi , Ziv Yohanan , Gil Senesh , Dikla Kersh , Alexey Tsypenyuk , Waina Michelle Chu , Alexander Barash
CPC分类号： A61F2/2418 , A61F2/2409 , A61F2/2433 , A61F2/2412 , A61F2/90 , A61F2220/0075 , A61F2230/0023 , A61F2230/0052 , A61F2250/0003 , A61F2250/0039 , A61F2250/0069 , A61F2310/00017 , A61F2310/00029 , A61F2310/00059
摘要： A system can include a delivery catheter comprising a balloon and an implantable prosthetic heart valve. The prosthetic valve can have a plastically expandable and compressible unitary frame comprising first, second, and third rows of angled struts that define two circumferentially extending rows of diamond-shaped cells that extend continuously around the frame, and a valvular structure comprising a plurality of leaflets. A cusp edge portion of each leaflet is connected to the frame by a skirt that is connected to and disposed between the frame and the cusp edge portions of the leaflets, the skirt being connected to consecutive struts in the first, second, and third rows of struts with sutures. The compressed prosthetic heart valve can be mounted around the balloon and radially expanded to the expanded configuration with the balloon inside a patient's body.
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公开(公告)号：US20230277313A1
公开(公告)日：2023-09-07
申请号：US18316942
申请日：2023-05-12
发明人： Nikolai Gurovich , Michael Bukin , Elena Sherman , Tamir S. Levi , Ziv Yohanan , Gil Senesh , Dikla Kersh , Alexey Tsypenyuk , Waina Michelle Chu , Alexander Barash
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2433 , A61F2/2409 , A61F2250/0069 , A61F2250/0003 , A61F2230/0052 , A61F2230/0023 , A61F2/2412 , A61F2/90
摘要： A prosthetic heart valve can include a radially expandable and compressible frame having an inflow end, an outflow end, and a plurality of struts. The prosthetic valve can further include a valvular structure comprising a plurality of leaflets, each leaflet comprising a coaptation edge portion and a cusp edge portion. The cusp edge portion of each leaflet can be folded toward the outflow end of the frame along a bending axis and a reinforcing member extends along an outflow surface of the cusp edge portion along the bending axis. The prosthetic heart valve can include a plurality of connecting skirts, each disposed between the cusp edge portion of an adjacent leaflet and the frame. First stitching secures the reinforcing member and the connecting skirts to the cusp edge portions and second stitching secures the connecting skirts to selected struts of the frame.
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公开(公告)号：US11096781B2
公开(公告)日：2021-08-24
申请号：US15664430
申请日：2017-07-31
发明人： Nikolay Gurovich , Michael Bukin , Elena Sherman , Tamir S. Levi , Ziv Yohanan , Gil Senesh , Dikla Kersh , Alexey M. Tsypenyuk , Waina Michelle Chu , Alexander Barash
IPC分类号： A61F2/24
摘要： A prosthetic heart valve can include a radially collapsible and expandable annular frame having a plurality of struts defining openings. The prosthetic heart valve can further include a plurality of leaflets that regulate the flow of blood through the frame. The prosthetic heart valve can also include a sealing member mounted on the frame and having an inner layer and an outer layer. At least the outer layer is mounted on the outside of the frame, and the inner layer covers at least the openings in the frame between adjacent cusp portions of adjacent leaflets and the inner layer does not cover one or more openings in the frame at locations facing the outflow surfaces of the leaflets to permit retrograde blood to flow through the one or more uncovered openings in the frame and into space between the outer layer and the frame.
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公开(公告)号：US20190192296A1
公开(公告)日：2019-06-27
申请号：US16252890
申请日：2019-01-21
发明人： Evan T. Schwartz , Sean Chow , Sandip Vasant Pawar , Darshin S. Patel , Chambory Chhe , Arpit Laddha , Ngoc Huong Thi Nguyen , Waina Michelle Chu , Yuanlong Du , Michael Bukin , Boaz Manash , Sara Haivatov , Tamir S. Levi
IPC分类号： A61F2/24
CPC分类号： A61F2/2442 , A61F2/2433 , A61F2/2436 , A61F2220/0075 , A61F2230/0091 , A61F2250/006
摘要： A prosthetic heart valve includes a frame having an inflow end and an outflow end, and defining a longitudinal axis. The prosthetic heart valve further includes a leaflet structure situated at least partially within the frame, and a covering disposed around the frame. The covering includes a first woven portion extending circumferentially around the frame and including a plurality of texturized strands or yarns extending along the longitudinal axis of the frame. The covering further includes a second woven portion extending circumferentially around the frame and spaced apart from the first woven portion along the longitudinal axis of the frame. The texturized strands extend along the longitudinal axis of the frame from the first woven portion to the second woven portion and form a floating portion between the first woven portion and the second woven portion.
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公开(公告)号：US20240335286A1
公开(公告)日：2024-10-10
申请号：US18737888
申请日：2024-06-07
发明人： Aviv Galon , Eran Hoffer , Carmel Peleg , Eric Michael Oberwise , Bezalel Haberman-Browns , Sarit Avivi , Haim Brauon , Ido Halabi , Jeffrey Michael Koslosky , Meir Abucasis , Waina Michelle Chu
IPC分类号： A61F2/24
CPC分类号： A61F2/2463 , A61F2/246 , A61F2/2466 , A61F2220/0091
摘要： A device or implant is configured to be positioned within a native heart valve to allow the native heart valve to form a more effective seal. One or more portions of device or implant can expand and contract. For example, one or more portions of the device or implant can narrow during delivery and expand on implantation on the native heart valve. Delivery systems are configured to narrow and expand the one or more portions of the device or implant.
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公开(公告)号：US20240189098A1
公开(公告)日：2024-06-13
申请号：US18443128
申请日：2024-02-15
发明人： Sara Tzadok , Khen Perlmutter , Darshin S. Patel , Boaz Manash , Ajay Chadha , Waina Michelle Chu , Chambory Chhe , Evan T. Schwartz , Sandip Vasant Pawar
CPC分类号： A61F2/2412 , A61F2/0077 , A61F2/2409 , A61F2/2418 , A61F2002/0086 , A61F2/243 , A61F2210/0076
摘要： A prosthetic heart valve has a frame including a plurality of strut members, the frame being radially expandable and collapsible between a collapsed state and an expanded state, the frame having an inflow end and an outflow end and defining a longitudinal axis. A leaflet structure is situated at least partially within the frame. A covering is disposed around an exterior of the frame and includes a cushioning layer, a first strip of material coupled to the cushioning layer and folded to encapsulate apices of the strut members of the inflow end of the frame, and a second strip of material coupled to the cushioning layer and folded to encapsulate apices of the strut members of the outflow end of the frame. The cushioning layer includes texturized filaments that provide compressible volume and a plush surface to the cushioning layer when the frame is in the expanded state.
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