Abstract:
Prosthetic heart valve assemblies and methods, apparatus, and systems used to deliver a prosthetic heart valve assembly. A prosthetic heart valve assembly includes an inner frame, a prosthetic leaflet section disposed within the inner frame extending between in inflow row of cells and an outflow row of cells of the inner frame, and an outer support stent. The inner frame is disposed within the outer support stent, and the outer support stent is coupled and/or fastened to the inner frame. The outer support stent includes a plurality leaflet capturing arms for capturing native leaflets between the leaflet capturing arms and a portion of the prosthetic heart valve assembly when the prosthetic heart valve assembly is implanted in a native valve. For example, the native leaflets can be frictionally secured between the leaflet capturing arms of the support stent and the inner frame.
Abstract:
Disclosed herein are representative embodiments of methods, apparatus, and systems used to deliver a prosthetic heart valve assembly. In embodiments, a prosthetic heart valve assembly, including a self-expandable support structure and a self-expanding heart valve, are advanced through the aortic arch of a patient using a delivery system. The support structure, which includes a plurality leaflet retaining arms, is at least partially expanded and positioned on or adjacent to the outflow side of the aortic valve. The prosthetic heart valve is positioned in the aortic valve. The prosthetic heart valve is expanded while it is within an interior of the support structure and while the support structure is positioned on or adjacent to the outflow side of the aortic valve, thereby causing one or more native leaflets of the aortic valve to be frictionally secured between the arms of the support structure and the expanded prosthetic heart valve.
Abstract:
A prosthetic valve assembly includes an annular frame having an inner radial surface, an outer radial surface, and defining an inner lumen. The prosthetic valve assembly further includes a leaflet assembly including at least one leaflet having an inner radial surface and an outer radial surface. The at least one leaflet is disposed at least partially within the inner lumen of the annular frame. The prosthetic valve assembly includes a crimping accessory device having a handle and at least one shielding member removably disposed between the outer radial surface of the at least one leaflet and the inner radial surface of the annular frame. The at least one shielding member is configured to reduce physical contact between the at least one leaflet and the inner radial surface of the annular frame.
Abstract:
A prosthetic valve assembly includes an annular frame having an inner radial surface, an outer radial surface, and defining an inner lumen. The prosthetic valve assembly further includes a leaflet assembly including at least one leaflet having an inner radial surface and an outer radial surface. The at least one leaflet is disposed at least partially within the inner lumen of the annular frame. The prosthetic valve assembly includes a crimping accessory device having a handle and at least one shielding member removably disposed between the outer radial surface of the at least one leaflet and the inner radial surface of the annular frame. The at least one shielding member is configured to reduce physical contact between the at least one leaflet and the inner radial surface of the annular frame.
Abstract:
Embodiments of an apparatus, and a method for crimping expandable stents or prosthetic valves having a radially expandable and compressible annular body and one or more protruding anchors extending from the body using the apparatus, where the apparatus comprise a housing, a plurality of circumferentially arranged nesting jaws, and an actuator configured to move the jaws radially inwardly to reduce the size of the crimping aperture, thereby radially compressing the annular body of the prosthetic valve or stent. In particular embodiments, a selected set of the jaws, each having a front side and a recessed portion in its front side adjacent to its inner end. The recessed portions of the selected jaws collectively are sized and shaped to receive the one or more anchors of the prosthetic valve when the annular body is positioned within the crimping aperture.
Abstract:
Disclosed herein are representative embodiments of methods, apparatus, and systems used to deliver a prosthetic heart valve to a deficient valve. In one embodiment, for instance, a support structure and an expandable prosthetic valve are advanced through the aortic arch of a patient using a delivery system. The support structure is delivered to a position on or adjacent to the surface of the outflow side of the aortic valve (the support structure defining a support-structure interior). The expandable prosthetic valve is delivered into the aortic valve and into the support-structure interior. The expandable prosthetic heart valve is expanded while the expandable prosthetic heart valve is in the support-structure interior and while the support structure is at the position on or adjacent to the surface of the outflow side of the aortic valve, thereby causing one or more native leaflets of the aortic valve to be frictionally secured between the support structure and the expanded prosthetic heart valve.
Abstract:
Prosthetic heart valve assemblies and methods, apparatus, and systems used to deliver a prosthetic heart valve assembly. A prosthetic heart valve assembly includes an inner frame, a prosthetic leaflet section disposed within the inner frame extending between in inflow row of cells and an outflow row of cells of the inner frame, and an outer support stent. The inner frame is disposed within the outer support stent, and the outer support stent is coupled and/or fastened to the inner frame. The outer support stent includes a plurality leaflet capturing arms for capturing native leaflets between the leaflet capturing arms and a portion of the prosthetic heart valve assembly when the prosthetic heart valve assembly is implanted in a native valve. For example, the native leaflets can be frictionally secured between the leaflet capturing arms of the support stent and the inner frame.
Abstract:
A valve repair device includes a pair of anchors and at least one leak inhibitor. The device can also include a spacer or coaptation element. The pair of anchors can be coupled to the spacer or coaptation element. The pair of anchors are movable between an open position and a closed position and are configured to attach the valve repair device to the native valve of the patient. The at least one leak inhibitor extends between the pair of anchors and is configured to inhibit retrograde blood flow through the device, for example, between one or more openings between leaflet portions that are in the anchors.
Abstract:
Embodiments of an apparatus, and a method for crimping expandable stents or prosthetic valves having a radially expandable and compressible annular body and one or more protruding anchors extending from the body using the apparatus, where the apparatus comprise a housing, a plurality of circumferentially arranged nesting jaws, and an actuator configured to move the jaws radially inwardly to reduce the size of the crimping aperture, thereby radially compressing the annular body of the prosthetic valve or stent. In particular embodiments, a selected set of the jaws, each having a front side and a recessed portion in its front side adjacent to its inner end. The recessed portions of the selected jaws collectively are sized and shaped to receive the one or more anchors of the prosthetic valve when the annular body is positioned within the crimping aperture.
Abstract:
Prosthetic heart valve assemblies and methods, apparatus, and systems used to deliver a prosthetic heart valve assembly. A prosthetic heart valve assembly includes an inner frame, a prosthetic leaflet section disposed within the inner frame extending between in inflow row of cells and an outflow row of cells of the inner frame, and an outer support stent. The inner frame is disposed within the outer support stent, and the outer support stent is coupled and/or fastened to the inner frame. The outer support stent includes a plurality leaflet capturing arms for capturing native leaflets between the leaflet capturing arms and a portion of the prosthetic heart valve assembly when the prosthetic heart valve assembly is implanted in a native valve. For example, the native leaflets can be frictionally secured between the leaflet capturing arms of the support stent and the inner frame.