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公开(公告)号：US11344409B2
公开(公告)日：2022-05-31
申请号：US16851959
申请日：2020-04-17
Applicant: Edwards Lifesciences Corporation
Inventor： David Robert Landon , Glen T. Rabito , Hieu Minh Luong
Abstract: Embodiments of a crimping device for crimping a radially expandable and compressible prosthetic valve are disclosed. A crimping device can comprise a housing configured to receive a prosthetic valve in a radially expanded state. The housing member can include a funnel segment and an outlet in communication with the funnel segment. The crimping device can further comprise an actuator rotatably coupled to the housing, wherein rotation of the actuator relative to the housing causes the prosthetic valve to move axially through the funnel segment such that at least a portion of the prosthetic valve compresses radially by engagement with the funnel segment and exits the crimping device via the outlet.
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公开(公告)号：US20210401575A1
公开(公告)日：2021-12-30
申请号：US17469817
申请日：2021-09-08
Applicant: Edwards Lifesciences Corporation
Inventor： David Robert Landon , Alexander H. Cooper , Julio Cesar Sanchez , Glen T. Rabito , J. Brent Ratz , Tarannum Ishaq Gutierrez , Ramon Aguilar, JR.
Abstract: Devices, systems and methods are described herein to provide improved steerability for delivering a prosthesis to a body location, for example, for delivering a replacement valve to a native valve location in a heart. Disclosed are a number of features that can improve steerability or release of the prosthesis into the body location. In one preferred delivery system, a proximal handle can be manipulated to apply tension to a pair of diametrically opposed axial runner wires extending through lumens in a wall of a flexible tubular shaft. By applying tension to a pair of axial runner wires, the tubular shaft can be stiffened along a plane extending substantially through the pair of axial runner wires, while the shaft is permitted to freely bend in a perpendicular plane. This feature advantageously provides the ability to adjust the steerability and flexibility of a tubular shaft to meet the requirements of a particular procedure.
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公开(公告)号：US10813757B2
公开(公告)日：2020-10-27
申请号：US16028172
申请日：2018-07-05
Applicant: Edwards Lifesciences Corporation
Inventor： Alexander H. Cooper , David Robert Landon , Kevin M. Stewart , Garrett Dallas Johnson , Glen T. Rabito , Tarannum Ishaq Gutierrez , Hiroshi Okabe , Ramon Aguilar, Jr. , Jesse Robert Edwards , Taylor Jacob Scheinblum , Patrick Chow , Julio Cesar Sanchez , Hieu Minh Luong
Abstract: Devices, systems and methods are described herein to provide improved steerability for delivering a prosthesis to a body location, for example, for delivering a replacement mitral valve to a native mitral valve location. The steerable delivery system can contain a steerable rail configured for multi-plane bending to direct a distal end of the delivery system.
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公开(公告)号：US20240261098A1
公开(公告)日：2024-08-08
申请号：US18625047
申请日：2024-04-02
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： Christopher J. Olson , Glen T. Rabito , Dustin P. Armer , Minh T. Ma , Devin H. Marr , Cheng-Tung Huang , Hiroshi Okabe , Kevin M. Stewart , Alison S. Curtis , Philip P. Corso, JR.
IPC: A61F2/24
CPC classification number: A61F2/2439 , A61F2/2418 , A61F2/243 , A61F2/2433 , A61F2/2436 , A61F2/2427 , A61F2220/0016 , A61F2220/005 , A61F2220/0075 , A61F2230/0054 , A61F2230/0076 , A61F2250/006
Abstract: Prosthetic heart valve assemblies and methods, apparatus, and systems used to deliver a prosthetic heart valve assembly. A prosthetic heart valve assembly includes an inner frame, a prosthetic leaflet section disposed within the inner frame extending between in inflow row of cells and an outflow row of cells of the inner frame, and an outer support stent. The inner frame is disposed within the outer support stent, and the outer support stent is coupled and/or fastened to the inner frame. The outer support stent includes a plurality leaflet capturing arms for capturing native leaflets between the leaflet capturing arms and a portion of the prosthetic heart valve assembly when the prosthetic heart valve assembly is implanted in a native valve. For example, the native leaflets can be frictionally secured between the leaflet capturing arms of the support stent and the inner frame.
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公开(公告)号：US11504229B2
公开(公告)日：2022-11-22
申请号：US16843122
申请日：2020-04-08
Applicant: Edwards Lifesciences Corporation
Inventor： Travis Zenyo Oba , Matthew A. Peterson , Glen T. Rabito , Alexander H. Cooper , David Robert Landon , J. Brent Ratz , Seung-Beom Yi
Abstract: A replacement mitral valve prosthesis includes a support structure and a valve body having three flexible leaflets. The support structure preferably includes an internal valve frame and an external sealing frame. The valve frame supports the flexible leaflets. The sealing frame is adapted to conform to the shape of the native mitral valve annulus. The sealing frame may be coupled to an inlet end of the valve frame, an outlet end of the valve frame, or both. A plurality of anchors is coupled to the outlet end of the valve frame. The anchors extend radially outwardly for placement behind native leaflets. The prosthesis preferably includes a skirt disposed along an exterior of the external sealing frame. The prosthesis is collapsible for delivery into the heart via a delivery catheter. The prosthesis is configured to self-expand for deployment in the heart when released from the delivery catheter.
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Patent Agency Ranking
公开(公告)号：US20220287833A1
公开(公告)日：2022-09-15
申请号：US17825071
申请日：2022-05-26
Applicant: Edwards Lifesciences Corporation
Inventor： David Robert Landon , Glen T. Rabito , Hieu Minh Luong
Abstract: Embodiments of a crimping device for crimping a radially expandable and compressible prosthetic valve are disclosed. A crimping device can comprise a housing configured to receive a prosthetic valve in a radially expanded state. The housing member can include a funnel segment and an outlet in communication with the funnel segment. The crimping device can further comprise an actuator rotatably coupled to the housing, wherein rotation of the actuator relative to the housing causes the prosthetic valve to move axially through the funnel segment such that at least a portion of the prosthetic valve compresses radially by engagement with the funnel segment and exits the crimping device via the outlet.
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公开(公告)号：US20210022863A1
公开(公告)日：2021-01-28
申请号：US17071745
申请日：2020-10-15
Applicant: Edwards Lifesciences Corporation
Inventor： Alexander H. Cooper , David Robert Landon , Kevin M. Stewart , Garrett Dallas Johnson , Glen T. Rabito , Tarannum Ishaq Gutierrez , Hiroshi Okabe , Ramon Aguilar, JR. , Jesse Robert Edwards , Taylor Jacob Scheinblum , Patrick Chow , Julio Cesar Sanchez , Hieu Minh Luong
Abstract: Devices, systems and methods are described herein to provide improved steerability for delivering a prosthesis to a body location, for example, for delivering a replacement mitral valve to a native mitral valve location. The steerable delivery system can contain a steerable rail configured for multi-plane bending to direct a distal end of the delivery system.
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公开(公告)号：US20200368015A1
公开(公告)日：2020-11-26
申请号：US16994080
申请日：2020-08-14
Applicant: Edwards Lifesciences Corporation
Inventor： J. Brent Ratz , Glen T. Rabito
IPC: A61F2/24
Abstract: Methods are described herein for delivering a replacement valve to a native valve location. In one method, ventricular anchors of the replacement valve are released and allowed to reverse orientation while positioned in the atrium of a human heart. After reversing orientation, the ventricular anchors extend in a generally proximal direction. The ventricular anchors can then be advanced through the annulus into the ventricle and then moved back toward the atrium to capture native valve leaflets between the main body and the ventricular anchors of the replacement valve. In one modification, the ventricular anchors are allowed to reverse orientation at a level adjacent the annulus. The implantation methods described herein are preferably performed via a transseptal delivery approach or a transapical delivery approach.
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公开(公告)号：US20200297481A1
公开(公告)日：2020-09-24
申请号：US16843122
申请日：2020-04-08
Applicant: Edwards Lifesciences Corporation
Inventor： Travis Zenyo Oba , Matthew A. Peterson , Glen T. Rabito , Alexander H. Cooper , David Robert Landon , J. Brent Ratz , Seung-Beom Yi
Abstract: A replacement mitral valve prosthesis includes a support structure and a valve body having three flexible leaflets. The support structure preferably includes an internal valve frame and an external sealing frame. The valve frame supports the flexible leaflets. The sealing frame is adapted to conform to the shape of the native mitral valve annulus. The sealing frame may be coupled to an inlet end of the valve frame, an outlet end of the valve frame, or both. A plurality of anchors is coupled to the outlet end of the valve frame. The anchors extend radially outwardly for placement behind native leaflets. The prosthesis preferably includes a skirt disposed along an exterior of the external sealing frame. The prosthesis is collapsible for delivery into the heart via a delivery catheter. The prosthesis is configured to self-expand for deployment in the heart when released from the delivery catheter.
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公开(公告)号：US10646339B2
公开(公告)日：2020-05-12
申请号：US15798035
申请日：2017-10-30
Applicant: Edwards Lifesciences Corporation
Inventor： J. Brent Ratz , Glen T. Rabito
IPC: A61F2/24
Abstract: Methods are described herein for delivering a replacement mitral valve to a native mitral valve location. In one method, ventricular anchors of the replacement mitral valve are released and allowed to reverse orientation while positioned in the left atrium of a human heart. After reversing orientation, the ventricular anchors extend in a generally proximal direction. The ventricular anchors can then be advanced through the mitral annulus into the left ventricle and then moved back toward the left atrium to capture native mitral valve leaflets between the main body and the ventricular anchors of the replacement mitral valve. In one modification, the ventricular anchors are allowed to reverse orientation at a level adjacent the mitral annulus. The implantation methods described herein are preferably performed via a transseptal delivery approach or a transapical delivery approach.
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