公开(公告)号：US20240335287A1

公开(公告)日：2024-10-10

申请号：US18745063

申请日：2024-06-17

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Mark Chau ,  Travis Zenyo Oba ,  Sam Shafigh ,  Jean-Pierre Michel Rabbah ,  David M. Taylor ,  Philippe Marchand ,  Madison Paige Kukura ,  Cristobal R. Hernandez ,  Nancy Hoang Khuu ,  Florian Georg Deuschl ,  Biswa P. Das ,  Andrew Charles May ,  Bhumica A. Amin

IPC: A61F2/24

CPC classification number: A61F2/2463 ,  A61F2/2466 ,  A61F2220/0008 ,  A61F2230/0008

Abstract: Systems and methods are disclosed for use with a valve of a heart. An implant (100) includes a wing (120); a flexible frame (124); and a pair of anchor receivers (150). A pair of shafts (660) are transluminally advanced through a catheter (40), while the shafts are each engaged with a respective anchor receiver (150), to deploy the implant out of the catheter such that the wing extends away from the anchor receivers and over a first leaflet of the valve and toward an opposing leaflet of the valve, with a contact face (122) of the wing facing the first leaflet. A pair of drivers (70) secure the implant using a pair of anchors (30) to anchor each anchor receiver to tissue at respective sites of the heart. Other implementations are also described.

公开(公告)号：US20230255758A1

公开(公告)日：2023-08-17

申请号：US18141208

申请日：2023-04-28

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Robert C. Taft ,  Travis Zenyo Oba

IPC: A61F2/24 ,  A61F2/95

CPC classification number: A61F2/2418 ,  A61F2/2433 ,  A61F2/95 ,  A61F2/9525 ,  A61F2230/005 ,  A61F2230/0054 ,  A61F2230/0065 ,  A61F2230/0067 ,  A61F2/958

Abstract: A crimping device for a prosthetic heart valve can comprise an annular outer frame and an inner frame extending through the outer frame, the inner frame comprising first and second axial end portions and a plurality of jaw guides extending therebetween, where the inner frame defines a central opening extending therethrough. The crimping device can comprise a plurality of jaws operatively coupled to the inner and outer frames, each jaw having an inner portion positioned within the central opening of the inner frame and an engagement portion configured to slide along a respective jaw guide, each jaw guide comprising an inclined guiderail extending between the first and second axial end portions. Relative axial motion between the outer and inner frames causes radial motion of the jaws for crimping a prosthetic device positioned within the central opening.

公开(公告)号：US11690711B2

公开(公告)日：2023-07-04

申请号：US16589014

申请日：2019-09-30

Applicant: Edwards Lifesciences Corporation

Inventor： Jackie P. Lau ,  John C. Peterson ,  Grace Myong Kim ,  John F. Migliazza ,  Travis Zenyo Oba

IPC: A61F2/24 ,  A61F2/00

CPC classification number: A61F2/2412 ,  A61F2/2427 ,  A61F2/0095 ,  A61F2/2418 ,  A61F2/2496 ,  A61F2250/0064 ,  A61F2250/0087 ,  A61F2250/0097

Abstract: A color-coded bioprosthetic valve system having a valve with an annular sewing ring, and a valve holder system with a holder sutured to the ring of the valve, a post operatively connected to the holder, and an adapter sutured to the post and having a color associated with the valve model and/or size. For example, the adapter may be blue to indicate that the valve of the system is a mitral valve of a particular type and/or size. The system may also include a flex handle that is configured to engage with the adapter. The handle has a color associated with the adapter such that a user is able to visually determine that the handle color matches the valve model. For example, the handle may have a grip that is colored blue to match the blue color of the adapter. Accordingly, the color-coded system enables users to confirm easily that the correct accessories such as the sizer or flex handle are being used with the correct valve.

公开(公告)号：US20230084393A1

公开(公告)日：2023-03-16

申请号：US18056691

申请日：2022-11-17

Applicant: Edwards Lifesciences Corporation

Inventor： Rafael Pintor ,  Mark Chau ,  Travis Zenyo Oba ,  August R. Yambao ,  Louis A. Campbell ,  Tammy Huntley ,  Qinggang Zeng ,  Carey L. Cristea ,  Faisal Kalam

IPC: A61F2/24

Abstract: A heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve has a base stent that is deployed at a treatment site, and a valve component configured to quickly connect to the base stent. The base stent may take the form of a self- or balloon-expandable stent that expands outward against the native valve with or without leaflet excision. The valve component has a non-expandable prosthetic valve and a self- or balloon-expandable coupling stent for attachment to the base stent, thereby fixing the position of the valve component relative to the base stent. The prosthetic valve may be a commercially available to valve with a sewing ring and the coupling stent attaches to the sewing ring. The system is particularly suited for rapid deployment of heart valves in a conventional open-heart surgical environment. A catheter-based system and method for deployment is provided.

公开(公告)号：US11504229B2

公开(公告)日：2022-11-22

申请号：US16843122

申请日：2020-04-08

Applicant: Edwards Lifesciences Corporation

Inventor： Travis Zenyo Oba ,  Matthew A. Peterson ,  Glen T. Rabito ,  Alexander H. Cooper ,  David Robert Landon ,  J. Brent Ratz ,  Seung-Beom Yi

IPC: A61F2/24 ,  A61L27/04 ,  A61L27/36

Abstract: A replacement mitral valve prosthesis includes a support structure and a valve body having three flexible leaflets. The support structure preferably includes an internal valve frame and an external sealing frame. The valve frame supports the flexible leaflets. The sealing frame is adapted to conform to the shape of the native mitral valve annulus. The sealing frame may be coupled to an inlet end of the valve frame, an outlet end of the valve frame, or both. A plurality of anchors is coupled to the outlet end of the valve frame. The anchors extend radially outwardly for placement behind native leaflets. The prosthesis preferably includes a skirt disposed along an exterior of the external sealing frame. The prosthesis is collapsible for delivery into the heart via a delivery catheter. The prosthesis is configured to self-expand for deployment in the heart when released from the delivery catheter.

公开(公告)号：US20220346955A1

公开(公告)日：2022-11-03

申请号：US17857688

申请日：2022-07-05

Applicant: Edwards Lifesciences Corporation

Inventor： Travis Zenyo Oba

IPC: A61F2/24

Abstract: A coil device for treating a heart valve includes a wire with a distal end and a proximal end with a cloth configured to promote ingrowth of tissue into the cloth covering at least a portion of the wire. The wire is formed at least partially from a memory metal that is pre-shaped to assume a helical coil shape with a diameter designed to provide a constricting force on a ventricle wall of a heart when the coil device is woven behind tissue features of trabeculae carneae associated with the ventricle wall.

公开(公告)号：US11412954B2

公开(公告)日：2022-08-16

申请号：US16356412

申请日：2019-03-18

Applicant: Edwards Lifesciences Corporation

Inventor： Louis A. Campbell ,  Travis Zenyo Oba ,  Rafael Pintor

IPC: A61B5/107 ,  A61F2/24 ,  A61B90/00 ,  A61B5/00

Abstract: An orifice-expanding device for measuring an expanded heart valve. The device includes a proximal handle having a shaft and an orifice-expanding device with a hub mounted to a distal end of the shaft and a plurality of arms evenly spaced around the axis and connected to the hub and extending therefrom in a distal direction to distal ends of the arms. The distal end of each arm has an expanding portion with an outer surface, the expanding portions being configured to move radially outward with respect to each other, wherein expansion of the expanding portions causes the distal ends of the arms to flex outward. A pressure-measuring device measures a pressure applied to the aortic valve annulus, and a size-measuring device measures a dimension of the aortic valve annulus after the annulus has been expanded.

公开(公告)号：US10918478B2

公开(公告)日：2021-02-16

申请号：US15682981

申请日：2017-08-22

Applicant: Edwards Lifesciences Corporation

Inventor： Rob Taft ,  Travis Zenyo Oba

IPC: B23P19/00 ,  A61F2/24 ,  A61F2/95 ,  A61F2/958

Abstract: A crimping system for a prosthetic heart valve comprises an elongate rigid body and a radially flexible, tubular sock. The body has an inner lumen extending along a central longitudinal axis between an insertion end and an outlet end. The inner lumen has a greater diameter at the insertion end than at the outlet end. The sock is configured to receive a radially compressible prosthetic heart valve in a radially expanded state within the sock and to pull the valve through the inner lumen of the rigid body from the insertion end to the outlet end with the sock being positioned between an outer surface of the valve and an inner surface of the rigid body. The valve is radially compressed by the inner surface of the rigid body as the sock pulls the valve along the longitudinal axis toward the outlet end of the lumen.

公开(公告)号：US10799346B2

公开(公告)日：2020-10-13

申请号：US16248706

申请日：2019-01-15

Applicant: Edwards Lifesciences Corporation

Inventor： Rafael Pintor ,  Mark Chau ,  Travis Zenyo Oba ,  August R. Yambao ,  Louis A. Campbell ,  Tammy Huntley ,  Qinggang Zeng ,  Carey L. Cristea ,  Faisal Kalam

IPC: A61F2/24

Abstract: A heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve has a base stent that is deployed at a treatment site, and a valve component configured to quickly connect to the base stent. The base stent may take the form of a self- or balloon-expandable stent that expands outward against the native valve with or without leaflet excision. The valve component has a non-expandable prosthetic valve and a self- or balloon-expandable coupling stent for attachment to the base stent, thereby fixing the position of the valve component relative to the base stent. The prosthetic valve may be a commercially available to valve with a sewing ring and the coupling stent attaches to the sewing ring. The system is particularly suited for rapid deployment of heart valves in a conventional open-heart surgical environment. A catheter-based system and method for deployment is provided.

公开(公告)号：US20200315795A1

公开(公告)日：2020-10-08

申请号：US16908375

申请日：2020-06-22

Applicant: Edwards Lifesciences Corporation

Inventor： Frederic B. Hodshon ,  Rafael Pintor ,  August R. Yambao ,  Abhishek Gautam ,  Louis A. Campbell ,  Lawrence J. Farhat ,  Tammy Huntley ,  Faisal Kalam ,  Travis Zenyo Oba ,  Qinggang Zeng

IPC: A61F2/24 ,  A61F2/00

Abstract: Packaging for prosthetic heart valves including an assembly for securely retaining a heart valve within ajar and facilitating retrieval therefrom. The assembly includes a packaging sleeve that fits closely within the jar and has a clip structure for securing a valve holder. Contrary to previous designs, in one embodiment the valve holder is directed downward into the jar, and the valve is retained with an inflow end upward. The valve may have flexible leaflets, and a leaflet parting member on the end of the shaft extends through the leaflets and couples with the valve holder. The assembly of the packaging sleeve, valve, and holder can then be removed from the jar and a valve delivery tube connected with the holder, or to the leaflet parting member. The packaging sleeve may be bifurcated into two halves connected at a living hinge to facilitate removal from around the valve/holder subassembly.