公开(公告)号：US11612328B2

公开(公告)日：2023-03-28

申请号：US16992157

申请日：2020-08-13

申请人： ELFI-TECH LTD.

发明人： Ilya Fine ,  Alexander Kaminsky

IPC分类号： A61B5/0205 ,  A61B5/026 ,  A61B5/0285 ,  A61B5/16 ,  A61B5/00

摘要： A method and apparatus for hemodynamically characterizing a neurological or fitness state by dynamic scattering light (DLS) is disclosed herein. In particular, a non-pulsatile blood-shear-rate-descriptive (BSRD) signal(s) is optically generated and analyzed. In some embodiments, the BSRD signal is generated dynamically so as to adaptively maximize (i.e. according to a bandpass or frequency-selection profile) a prominence of a predetermined non-pulsatile physiological signal within the BSRD. In some embodiments, the BSRD is subjected to a stochastic or stationary-status analysis. Alternatively or additionally, the neurological or fitness state may be computed from multiple BSRDs, including two or more of: (i) a [sub −200 Hz, ˜300 Hz] BSRD signal; (ii) a [˜300 Hz, ˜1000 Hz] signal; (iii) a [˜1000 Hz, ˜4000 Hz] signal and (iv) a [˜4000 Hz, z Hz] (z>=7,000) signal.

公开(公告)号：US20180310891A1

公开(公告)日：2018-11-01

申请号：US15938533

申请日：2018-03-28

申请人： ELFI-TECH LTD.

发明人： Ilya FINE ,  Alexander Kaminsky

IPC分类号： A61B5/00 ,  A61B5/026 ,  A61B5/022

摘要： Methods and systems of optically measuring systolic and/or diastolic blood pressure of a mammal having biological tissue are disclosed herein. In some embodiments, the system comprises an optical blood motion sensor, a gas-sealable inflatable cushion having a flexible and transparent (FOT) barrier section, and an optical blood motion sensor comprising a laser. When pressure (e.g. at least systolic pressure) illuminates the tissue, laser light may pass en route to the tissue through the FOT sealing barrier section of the gas-sealable inflatable cushion as well as cushion interior. In some embodiments, a rigid restrictor comprising an optically transparent section is provided, and laser light also passes through the optically transparent section of the rigid restrictor en route to the biological tissue.

公开(公告)号：US20180153420A1

公开(公告)日：2018-06-07

申请号：US15811823

申请日：2017-11-14

申请人： ELFI-TECH LTD.

发明人： Ilya FINE ,  Alexander Kaminsky

IPC分类号： A61B5/024 ,  A61B5/02 ,  A61B5/026 ,  A61B5/00 ,  A61B5/022

CPC分类号： A61B5/02416 ,  A61B5/02035 ,  A61B5/02233 ,  A61B5/0261 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/7207 ,  A61B5/7239

摘要： Apparatus and methods for optical and non-invasive measurement of cardiovascular fitness and/or stress and/or physiological parameters are disclosed herein.

公开(公告)号：US10952622B2

公开(公告)日：2021-03-23

申请号：US15770590

申请日：2016-08-15

申请人： ELFI-TECH LTD.

发明人： Ilya Fine ,  Alexander Kaminsky

IPC分类号： A61B5/0205 ,  A61B5/026 ,  A61B5/0285 ,  A61B5/16 ,  A61B5/00

摘要： A method and apparatus for hemodynamically characterizing a neurological or fitness state by dynamic scattering light (DLS) is disclosed herein. In particular, a non-pulsatile blood-shear-rate-descriptive (BSRD) signal(s) is optically generated and analyzed. In some embodiments, the BSRD signal is generated dynamically so as to adaptively maximize (i.e. according to a bandpass or frequency-selection profile) a prominence of a predetermined non-pulsatile physiological signal within the BSRD. In some embodiments, the BSRD is subjected to a stochastic or stationary-status analysis. Alternatively or additionally, the neurological or fitness state may be computed from multiple BSRDs, including two or more of: (i) a [sub-200 Hz, ˜300 Hz] BSRD signal; (ii) a [˜300 Hz, ˜1000 Hz] signal; (iii) a [˜1000 Hz, ˜4000 Hz] signal and (iv) a [˜4000 Hz, z Hz] (z>=7,000) signal.

公开(公告)号：US20190298186A1

公开(公告)日：2019-10-03

申请号：US16382255

申请日：2019-04-12

申请人： ELFI-TECH LTD.

发明人： Ilya Fine ,  Alexander Kaminsky

IPC分类号： A61B5/026 ,  A61B5/00 ,  A61B5/022

摘要： Methods and systems of optically measuring systolic and/or diastolic blood pressure of a mammal having biological tissue are disclosed herein. In some embodiments, the system comprises an optical blood motion sensor, a gas-sealable inflatable cushion having a flexible and transparent (FOT) barrier section, and an optical blood motion sensor comprising a laser. When pressure (e.g. at least systolic pressure) illuminates the tissue, laser light may pass en route to the tissue through the FOT sealing barrier section of the gas-sealable inflatable cushion as well as cushion interior. In some embodiments, a rigid restrictor comprising an optically transparent section is provided, and laser light also passes through the optically transparent section of the rigid restrictor en route to the biological tissue.

公开(公告)号：US11350837B2

公开(公告)日：2022-06-07

申请号：US16382255

申请日：2019-04-12

申请人： ELFI-TECH LTD.

发明人： Ilya Fine ,  Alexander Kaminsky

IPC分类号： A61B5/026 ,  A61B5/00 ,  A61B5/022 ,  A61B5/1455 ,  A61B5/024

摘要： Methods and systems of optically measuring systolic and/or diastolic blood pressure of a mammal having biological tissue are disclosed herein. In some embodiments, the system comprises an optical blood motion sensor, a gas-sealable inflatable cushion having a flexible and transparent (FOT) barrier section, and an optical blood motion sensor comprising a laser. When pressure (e.g. at least systolic pressure) illuminates the tissue, laser light may pass en route to the tissue through the FOT sealing barrier section of the gas-sealable inflatable cushion as well as cushion interior. In some embodiments, a rigid restrictor comprising an optically transparent section is provided, and laser light also passes through the optically transparent section of the rigid restrictor en route to the biological tissue.

公开(公告)号：US20220183579A1

公开(公告)日：2022-06-16

申请号：US17533455

申请日：2021-11-23

申请人： ELFI-TECH LTD.

发明人： Ilya FINE ,  Alexander Kaminsky

IPC分类号： A61B5/0225 ,  A61B5/026 ,  A61B5/022

摘要： Methods and systems of optically measuring systolic and/or diastolic blood pressure of a mammal having biological tissue are disclosed herein. In some embodiments, the system comprises an optical blood motion sensor, a gas-sealable inflatable cushion having a flexible and transparent (FOT) barrier section, and an optical blood motion sensor comprising a laser. When pressure (e.g. at least systolic pressure) illuminates the tissue, laser light may pass en route to the tissue through the FOT sealing barrier section of the gas-sealable inflatable cushion as well as cushion interior. In some embodiments, a rigid restrictor comprising an optically transparent section is provided, and laser light also passes through the optically transparent section of the rigid restrictor en route to the biological tissue.

公开(公告)号：US11134901B2

公开(公告)日：2021-10-05

申请号：US15938533

申请日：2018-03-28

申请人： ELFI-TECH LTD.

发明人： Ilya Fine ,  Alexander Kaminsky

IPC分类号： A61B5/00 ,  A61B5/022 ,  A61B5/026 ,  A61B5/021 ,  A61B5/024 ,  A61B5/02

摘要： Methods and systems of optically measuring systolic and/or diastolic blood pressure of a mammal having biological tissue are disclosed herein. In some embodiments, the system comprises an optical blood motion sensor, a gas-sealable inflatable cushion having a flexible and transparent (FOT) barrier section, and an optical blood motion sensor comprising a laser. When pressure (e.g. at least systolic pressure) illuminates the tissue, laser light may pass en route to the tissue through the FOT sealing barrier section of the gas-sealable inflatable cushion as well as cushion interior. In some embodiments, a rigid restrictor comprising an optically transparent section is provided, and laser light also passes through the optically transparent section of the rigid restrictor en route to the biological tissue.

公开(公告)号：US20210093204A1

公开(公告)日：2021-04-01

申请号：US16992157

申请日：2020-08-13

申请人： ELFI-TECH LTD.

发明人： Ilya FINE ,  Alexander Kaminsky

IPC分类号： A61B5/0205 ,  A61B5/026 ,  A61B5/0285 ,  A61B5/16 ,  A61B5/00

摘要： A method and apparatus for hemodynamically characterizing a neurological or fitness state by dynamic scattering light (DLS) is disclosed herein. In particular, a non-pulsatile blood-shear-rate-descriptive (BSRD) signal(s) is optically generated and analyzed. In some embodiments, the BSRD signal is generated dynamically so as to adaptively maximize (i.e. according to a bandpass or frequency-selection profile) a prominence of a predetermined non-pulsatile physiological signal within the BSRD. In some embodiments, the BSRD is subjected to a stochastic or stationary-status analysis. Alternatively or additionally, the neurological or fitness state may be computed from multiple BSRDs, including two or more of: (i) a [sub-200 Hz, ˜300 Hz] BSRD signal; (ii) a [˜300 Hz, ˜1000 Hz] signal; (iii) a [˜1000 Hz, ˜4000 Hz] signal and (iv) a [4000 Hz, z Hz] (z>=7,000) signal.