公开(公告)号：US20180310891A1

公开(公告)日：2018-11-01

申请号：US15938533

申请日：2018-03-28

申请人： ELFI-TECH LTD.

发明人： Ilya FINE ,  Alexander Kaminsky

IPC分类号： A61B5/00 ,  A61B5/026 ,  A61B5/022

摘要： Methods and systems of optically measuring systolic and/or diastolic blood pressure of a mammal having biological tissue are disclosed herein. In some embodiments, the system comprises an optical blood motion sensor, a gas-sealable inflatable cushion having a flexible and transparent (FOT) barrier section, and an optical blood motion sensor comprising a laser. When pressure (e.g. at least systolic pressure) illuminates the tissue, laser light may pass en route to the tissue through the FOT sealing barrier section of the gas-sealable inflatable cushion as well as cushion interior. In some embodiments, a rigid restrictor comprising an optically transparent section is provided, and laser light also passes through the optically transparent section of the rigid restrictor en route to the biological tissue.

公开(公告)号：US20180160913A1

公开(公告)日：2018-06-14

申请号：US15702585

申请日：2017-09-12

申请人： ELFI-TECH LTD.

发明人： Ilya FINE

IPC分类号： A61B5/0205 ,  A61B5/0265 ,  A61B5/00 ,  A61B5/1455 ,  A61B5/145 ,  A61B5/024

CPC分类号： A61B5/0205 ,  A61B5/024 ,  A61B5/0265 ,  A61B5/14532 ,  A61B5/14551 ,  A61B5/14552 ,  A61B5/7246 ,  A61B5/7278

摘要： A system, method and medical tool are presented for use in non-invasive in vivo determination of at least one desired parameter or condition of a subject having a scattering medium in a target region. The measurement system comprises an illuminating system, a detection system, and a control system. The illumination system comprises at least one light source configured for generating partially or entirely coherent light to be applied to the target region to cause a light response signal from the illuminated region. The detection system comprises at least one light detection unit configured for detecting time-dependent fluctuations of the intensity of the light response and generating data indicative of a dynamic light scattering (DLS) measurement. The control system is configured and operable to receive and analyze the data indicative of the DLS measurement to determine the at least one desired parameter or condition, and generate output data indicative thereof.

公开(公告)号：US20180153420A1

公开(公告)日：2018-06-07

申请号：US15811823

申请日：2017-11-14

申请人： ELFI-TECH LTD.

发明人： Ilya FINE ,  Alexander Kaminsky

IPC分类号： A61B5/024 ,  A61B5/02 ,  A61B5/026 ,  A61B5/00 ,  A61B5/022

CPC分类号： A61B5/02416 ,  A61B5/02035 ,  A61B5/02233 ,  A61B5/0261 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/7207 ,  A61B5/7239

摘要： Apparatus and methods for optical and non-invasive measurement of cardiovascular fitness and/or stress and/or physiological parameters are disclosed herein.

公开(公告)号：US20140094666A1

公开(公告)日：2014-04-03

申请号：US13629752

申请日：2012-09-28

申请人： ELFI-TECH LTD.

发明人： Ilya FINE

IPC分类号： A61B5/0205 ,  A61B5/145 ,  A61B5/1455

CPC分类号： A61B5/0205 ,  A61B5/024 ,  A61B5/0265 ,  A61B5/14532 ,  A61B5/14551 ,  A61B5/14552 ,  A61B5/7246 ,  A61B5/7278

摘要： A system, method and medical tool are presented for use in non-invasive in vivo determination of at least one desired parameter or condition of a subject having a scattering medium in a target region. The measurement system comprises an illuminating system, a detection system, and a control system. The illumination system comprises at least one light source configured for generating partially or entirely coherent light to be applied to the target region to cause a light response signal from the illuminated region. The detection system comprises at least one light detection unit configured for detecting time-dependent fluctuations of the intensity of the light response and generating data indicative of a dynamic light scattering (DLS) measurement. The control system is configured and operable to receive and analyze the data indicative of the DLS measurement to determine the at least one desired parameter or condition, and generate output data indicative thereof.

摘要翻译： 本发明提供一种系统，方法和医疗工具，用于在目标区域中具有散射介质的受试者的至少一个期望参数或状况的非侵入式体内测定中。 测量系统包括照明系统，检测系统和控制系统。 所述照明系统包括至少一个光源，所述至少一个光源被配置用于产生要施加到所述目标区域的部分或全部相干光，以引起来自所述照明区域的光响应信号。 检测系统包括至少一个光检测单元，其被配置用于检测光响应的强度的时间相关波动并产生指示动态光散射（DLS）测量的数据。 控制系统被配置和操作以接收和分析指示DLS测量的数据以确定至少一个期望的参数或条件，并且生成指示其的输出数据。

公开(公告)号：US20220183579A1

公开(公告)日：2022-06-16

申请号：US17533455

申请日：2021-11-23

申请人： ELFI-TECH LTD.

发明人： Ilya FINE ,  Alexander Kaminsky

IPC分类号： A61B5/0225 ,  A61B5/026 ,  A61B5/022

摘要： Methods and systems of optically measuring systolic and/or diastolic blood pressure of a mammal having biological tissue are disclosed herein. In some embodiments, the system comprises an optical blood motion sensor, a gas-sealable inflatable cushion having a flexible and transparent (FOT) barrier section, and an optical blood motion sensor comprising a laser. When pressure (e.g. at least systolic pressure) illuminates the tissue, laser light may pass en route to the tissue through the FOT sealing barrier section of the gas-sealable inflatable cushion as well as cushion interior. In some embodiments, a rigid restrictor comprising an optically transparent section is provided, and laser light also passes through the optically transparent section of the rigid restrictor en route to the biological tissue.

公开(公告)号：US20210093204A1

公开(公告)日：2021-04-01

申请号：US16992157

申请日：2020-08-13

申请人： ELFI-TECH LTD.

发明人： Ilya FINE ,  Alexander Kaminsky

IPC分类号： A61B5/0205 ,  A61B5/026 ,  A61B5/0285 ,  A61B5/16 ,  A61B5/00

摘要： A method and apparatus for hemodynamically characterizing a neurological or fitness state by dynamic scattering light (DLS) is disclosed herein. In particular, a non-pulsatile blood-shear-rate-descriptive (BSRD) signal(s) is optically generated and analyzed. In some embodiments, the BSRD signal is generated dynamically so as to adaptively maximize (i.e. according to a bandpass or frequency-selection profile) a prominence of a predetermined non-pulsatile physiological signal within the BSRD. In some embodiments, the BSRD is subjected to a stochastic or stationary-status analysis. Alternatively or additionally, the neurological or fitness state may be computed from multiple BSRDs, including two or more of: (i) a [sub-200 Hz, ˜300 Hz] BSRD signal; (ii) a [˜300 Hz, ˜1000 Hz] signal; (iii) a [˜1000 Hz, ˜4000 Hz] signal and (iv) a [4000 Hz, z Hz] (z>=7,000) signal.

公开(公告)号：US20190008397A1

公开(公告)日：2019-01-10

申请号：US15770590

申请日：2016-08-15

申请人： ELFI-TECH LTD.

发明人： Ilya FINE ,  Alexander KAMINSKY

IPC分类号： A61B5/0205 ,  A61B5/026 ,  A61B5/0285 ,  A61B5/16 ,  A61B5/00

摘要： A method and apparatus for hemodynamically characterizing a neurological or fitness state by dynamic scattering light (DLS) is disclosed herein. In particular, a non-pulsatile blood-shear-rate-descriptive (BSRD) signal(s) is optically generated and analyzed. In some embodiments, the BSRD signal is generated dynamically so as to adaptively maximize (i.e. according to a bandpass or frequency-selection profile) a prominence of a predetermined non-pulsatile physiological signal within the BSRD. In some embodiments, the BSRD is subjected to a stochastic or stationary-status analysis. Alternatively or additionally, the neurological or fitness state may be computed from multiple BSRDs, including two or more of: (i) a [sub-200 Hz, ˜300 Hz] BSRD signal; (ii) a [˜300 Hz, ˜1000 Hz] signal; (iii) a [˜1000 Hz, ˜4000 Hz] signal and (iv) a [˜4000 Hz, z Hz] (z>=7,000) signal.