公开(公告)号：US20150298070A1

公开(公告)日：2015-10-22

申请号：US14648925

申请日：2013-12-10

Applicant: EMD MILLIPORE CORPORATION

Inventor： Mikhail Koslov ,  Gabriel Tkacik ,  Onur Y. Kas ,  Ajish Potty ,  Jigneshkumar Patel

IPC: B01D71/56 ,  B01D69/06 ,  B01D61/14

CPC classification number: B01D71/56 ,  A61L2/022 ,  B01D39/1623 ,  B01D61/145 ,  B01D67/0004 ,  B01D69/06 ,  B01D2239/025 ,  B01D2239/0631 ,  B01D2239/0654 ,  B01D2239/1233 ,  B01D2323/39

Abstract: A porous electrospun polymeric nanofiber liquid filtration medium, such as an electrospun mats, used for the removal of viral particles (e.g., parvovirus) and other particles in the 18 nm to 30 nm size range from fluid streams, having a mean flow bubble point measured with perfluorohexane above 100 psi. The electrospun medium includes nanofibers having an average fiber diameter of about 6 nm to about 13 nm, and the nanofiber liquid filtration medium has a mean pore size ranging from about 0.01 um to about 0.03 um, a porosity ranging from about 80% to about 95%, a thickness ranging from about 1 um to about 100 um, and a liquid permeability greater than about 10 LMH/psi. The high porosity of the electro-spun mats enable much higher water fluxes, thus reducing the time required to complete virus filtration steps on a fluid stream.

Abstract translation: 用于从流体流中除去病毒颗粒（例如细小病毒）和其他颗粒的多孔电纺聚合物纳米纤维液体过滤介质，例如电纺丝垫，其具有测量的平均流动泡点 全氟己烷高于100psi。 电纺介质包括平均纤维直径为约6nm至约13nm的纳米纤维，纳米纤维液体过滤介质的平均孔径为约0.01μm至约0.03μm，孔隙率为约80％至约95 ％，约1μm至约100μm的厚度，以及大于约10LHH / psi的液体渗透性。 电纺垫的高孔隙度使得能够获得更高的水通量，从而减少在流体流上完成病毒过滤步骤所需的时间。

公开(公告)号：US20230123639A1

公开(公告)日：2023-04-20

申请号：US18066610

申请日：2022-12-15

Applicant: EMD Millipore Corporation

Inventor： Mikhail Kozlov ,  Gabriel Tkacik ,  Onur Y. Kas ,  Ajish Potty ,  Jigneshkumar Patel

IPC: B01D71/56 ,  B01D61/14 ,  B01D69/06 ,  B01D67/00 ,  B01D39/16 ,  A61L2/02

Abstract: A porous electrospun polymeric nanofiber liquid filtration medium, such as an electrospun mats, used for the removal of viral particles (e.g., parvovirus) and other particles in the 18 nm to 30 nm size range from fluid streams, having a mean flow bubble point measured with perfluorohexane above 100 psi. The electrospun medium includes nanofibers having an average fiber diameter of about 6 nm to about 13 nm, and the nanofiber liquid filtration medium has a mean pore size ranging from about 0.01 μm to about 0.03 μm, a porosity ranging from about 80% to about 95%, a thickness ranging from about 1 μm to about 100 μm, and a liquid permeability greater than about 10 LMH/psi. The high porosity of the electrospun mats enable much higher water fluxes, thus reducing the time required to complete virus filtration steps on a fluid stream.