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公开(公告)号:US20210355606A1
公开(公告)日:2021-11-18
申请号:US17290024
申请日:2019-10-31
Applicant: EMD Millipore Corporation
Inventor: Onur Y. Kas , Thang Nguyen , Nitin Satav , Martin Cuddy
Abstract: Provided herein are electrospirming apparatuses and methods for efficient production of nanofiber structures.
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公开(公告)号:US20150298070A1
公开(公告)日:2015-10-22
申请号:US14648925
申请日:2013-12-10
Applicant: EMD MILLIPORE CORPORATION
Inventor: Mikhail Koslov , Gabriel Tkacik , Onur Y. Kas , Ajish Potty , Jigneshkumar Patel
CPC classification number: B01D71/56 , A61L2/022 , B01D39/1623 , B01D61/145 , B01D67/0004 , B01D69/06 , B01D2239/025 , B01D2239/0631 , B01D2239/0654 , B01D2239/1233 , B01D2323/39
Abstract: A porous electrospun polymeric nanofiber liquid filtration medium, such as an electrospun mats, used for the removal of viral particles (e.g., parvovirus) and other particles in the 18 nm to 30 nm size range from fluid streams, having a mean flow bubble point measured with perfluorohexane above 100 psi. The electrospun medium includes nanofibers having an average fiber diameter of about 6 nm to about 13 nm, and the nanofiber liquid filtration medium has a mean pore size ranging from about 0.01 um to about 0.03 um, a porosity ranging from about 80% to about 95%, a thickness ranging from about 1 um to about 100 um, and a liquid permeability greater than about 10 LMH/psi. The high porosity of the electro-spun mats enable much higher water fluxes, thus reducing the time required to complete virus filtration steps on a fluid stream.
Abstract translation: 用于从流体流中除去病毒颗粒(例如细小病毒)和其他颗粒的多孔电纺聚合物纳米纤维液体过滤介质,例如电纺丝垫,其具有测量的平均流动泡点 全氟己烷高于100psi。 电纺介质包括平均纤维直径为约6nm至约13nm的纳米纤维,纳米纤维液体过滤介质的平均孔径为约0.01μm至约0.03μm,孔隙率为约80%至约95 %,约1μm至约100μm的厚度,以及大于约10LHH / psi的液体渗透性。 电纺垫的高孔隙度使得能够获得更高的水通量,从而减少在流体流上完成病毒过滤步骤所需的时间。
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公开(公告)号:US20230123639A1
公开(公告)日:2023-04-20
申请号:US18066610
申请日:2022-12-15
Applicant: EMD Millipore Corporation
Inventor: Mikhail Kozlov , Gabriel Tkacik , Onur Y. Kas , Ajish Potty , Jigneshkumar Patel
Abstract: A porous electrospun polymeric nanofiber liquid filtration medium, such as an electrospun mats, used for the removal of viral particles (e.g., parvovirus) and other particles in the 18 nm to 30 nm size range from fluid streams, having a mean flow bubble point measured with perfluorohexane above 100 psi. The electrospun medium includes nanofibers having an average fiber diameter of about 6 nm to about 13 nm, and the nanofiber liquid filtration medium has a mean pore size ranging from about 0.01 μm to about 0.03 μm, a porosity ranging from about 80% to about 95%, a thickness ranging from about 1 μm to about 100 μm, and a liquid permeability greater than about 10 LMH/psi. The high porosity of the electrospun mats enable much higher water fluxes, thus reducing the time required to complete virus filtration steps on a fluid stream.
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公开(公告)号:US20210254248A1
公开(公告)日:2021-08-19
申请号:US17167371
申请日:2021-02-04
Applicant: EMD Millipore Corporation
Inventor: Nitin Satav , Martin Cuddy, JR. , Xiaozhu Zhou , Saptarshi Chattopadhyay , William Trinh , Onur Y. Kas , David Nhiem
Abstract: Provided herein are sterilizable porous filtration media and methods of making and using the same.
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公开(公告)号:US10252199B2
公开(公告)日:2019-04-09
申请号:US15448248
申请日:2017-03-02
Applicant: EMD Millipore Corporation
Inventor: Onur Y. Kas , Mikhail Kozlov , Wilson Moya , Sherry A. Leon , Philip Goddard , Jibin Hao , Gabriel Tkacik
IPC: B01D39/16 , B01D39/18 , B01D39/14 , A61L2/02 , C12N7/00 , D01D1/02 , D01D5/00 , D01F6/96 , B01D69/02 , B01D69/10 , B01D39/04 , B01D39/00 , B01D67/00 , B01D61/14
Abstract: A method for removing retroviruses from liquid samples and a nanofiber containing liquid filtration medium that simultaneously exhibits high liquid permeability and high microorganism retention is disclosed. Retroviruses are removed from a liquid by passing the liquid through a porous nanofiber containing filtration medium having a retrovirus LRV greater than about 6, and the nanofiber(s) has a diameter from about 10 nm to about 100 nm. The filtration medium can be in the form of a fibrous electrospun polymeric nanofiber liquid filtration medium mat.
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公开(公告)号:US20170173511A1
公开(公告)日:2017-06-22
申请号:US15448248
申请日:2017-03-02
Applicant: EMD Millipore Corporation
Inventor: Onur Y. Kas , Mikhail Kozlov , Wilson Moya , Sherry A. Leon , Philip Goddard , Jibin Hao , Gabriel Tkacik
CPC classification number: B01D39/1607 , A61L2/022 , B01D39/00 , B01D39/04 , B01D39/14 , B01D39/16 , B01D39/1615 , B01D39/1623 , B01D39/18 , B01D61/14 , B01D67/0004 , B01D67/002 , B01D69/02 , B01D69/10 , B01D2239/0208 , B01D2239/0216 , B01D2239/025 , B01D2239/0442 , B01D2239/0631 , B01D2239/10 , B01D2239/1233 , B01D2323/39 , B01D2323/42 , B01D2325/20 , C12N7/00 , C12N2740/16051 , D01D1/02 , D01D5/0092 , D01F6/96 , D10B2505/04
Abstract: A method for removing retroviruses from liquid samples and a nanofiber containing liquid filtration medium that simultaneously exhibits high liquid permeability and high microorganism retention is disclosed. Retroviruses are removed from a liquid by passing the liquid through a porous nanofiber containing filtration medium having a retrovirus LRV greater than about 6, and the nanofiber(s) has a diameter from about 10 nm to about 100 nm. The filtration medium can be in the form of a fibrous electrospun polymeric nanofiber liquid filtration medium mat.
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