公开(公告)号：US20190111395A1

公开(公告)日：2019-04-18

申请号：US16094237

申请日：2017-04-20

Applicant: EMD Millipore Corporation

Inventor： Kurt E. Greenizen ,  Christopher A. Scott ,  Paul Sydlowski ,  John Doyle ,  Ryan A. Amara

IPC: B01D63/08 ,  B25B5/08 ,  B25B5/04 ,  B25B5/14 ,  B01L9/00 ,  B01L3/00 ,  G01N1/40

Abstract: A clamp including a first jaw member having a camming surface, a second jaw member pivotable with respect to the first jaw member, a first biasing member biasing the first and second jaw members to a first position; and a locking mechanism that includes a cam or roller for cooperating with the camming surface of the jaw member, and a second biasing member biasing the cam or roller against the camming surface to lock the first and second jaw members in a second position. An optional alignment collar can be used to align components of the filtration apparatus prior to clamping. Filtration apparatus including the clamp, and also optionally including the alignment collar, is also disclosed.

公开(公告)号：US09891218B2

公开(公告)日：2018-02-13

申请号：US15006153

申请日：2016-01-26

Applicant: EMD Millipore Corporation

Inventor： Chris Scott ,  Phillip Clark ,  Kurt E. Greenizen ,  Ryan A. Amara ,  Robert Colonna

IPC: G01N21/75 ,  G01N33/558 ,  G01N33/543 ,  B01L3/00 ,  B01L9/00 ,  G01N33/569 ,  B01J20/28

CPC classification number: G01N33/558 ,  B01J20/28033 ,  B01J20/28035 ,  B01J20/2804 ,  B01L3/5023 ,  B01L9/52 ,  B01L2200/025 ,  B01L2300/0609 ,  B01L2300/0681 ,  B01L2300/069 ,  B01L2300/0809 ,  B01L2300/12 ,  B01L2300/126 ,  B01L2400/0487 ,  B01L2400/049 ,  G01N33/54366 ,  G01N33/56911 ,  G01N2469/10 ,  G01N2469/20

Abstract: The embodiments disclosed herein are directed to an apparatus useful in conducting detection of compounds on blotting membranes. The device is comprised of several layers including a porous support layer below the blotting membrane(s), a flow distributor above the blotting membrane(s) and optionally a well on the flow distributor to contain the liquid to the desired area and to allow for lower starting volumes of such liquid. Preferably, the flow distributor is a non-binding or low binding hydrophilic porous membrane such as a 0.22 micron membrane and the support layer is a grid or sintered porous material. The distributor and support are held together to form an envelope around the membrane(s). The use of a hinge, clips and other such devices is preferred in doing so.

公开(公告)号：US20160178625A1

公开(公告)日：2016-06-23

申请号：US15006153

申请日：2016-01-26

Applicant: EMD Millipore Corporation

Inventor： Chris Scott ,  Phillip Clark ,  Kurt E. Greenizen ,  Ryan A. Amara ,  Robert Colonna

IPC: G01N33/558 ,  B01L9/00 ,  B01L3/00

CPC classification number: G01N33/558 ,  B01J20/28033 ,  B01J20/28035 ,  B01J20/2804 ,  B01L3/5023 ,  B01L9/52 ,  B01L2200/025 ,  B01L2300/0609 ,  B01L2300/0681 ,  B01L2300/069 ,  B01L2300/0809 ,  B01L2300/12 ,  B01L2300/126 ,  B01L2400/0487 ,  B01L2400/049 ,  G01N33/54366 ,  G01N33/56911 ,  G01N2469/10 ,  G01N2469/20

Abstract: The embodiments disclosed herein are directed to an apparatus useful in conducting detection of compounds on blotting membranes. The device is comprised of several layers including a porous support layer below the blotting membrane(s), a flow distributor above the blotting membrane(s) and optionally a well on the flow distributor to contain the liquid to the desired area and to allow for lower starting volumes of such liquid. Preferably, the flow distributor is a non-binding or low binding hydrophilic porous membrane such as a 0.22 micron membrane and the support layer is a grid or sintered porous material. The distributor and support are held together to form an envelope around the membrane(s). The use of a hinge, clips and other such devices is preferred in doing so.

Abstract translation: 本文公开的实施方案涉及用于在印迹膜上进行化合物检测的装置。 该装置包括多个层，包括印迹膜下面的多孔支撑层，印迹膜上方的流量分布器，以及任选的流量分配器上的孔，以将液体包含到期望的区域并允许 降低这种液体的起始体积。 优选地，流动分配器是非结合或低结合的亲水性多孔膜，例如0.22微米的膜，并且支撑层是格栅或烧结的多孔材料。 分配器和支撑件保持在一起以在膜周围形成一个信封。 在这样做时优选使用铰链，夹子和其它这样的装置。

公开(公告)号：US11433355B2

公开(公告)日：2022-09-06

申请号：US16094237

申请日：2017-04-20

Applicant: EMD Millipore Corporation

Inventor： Kurt E. Greenizen ,  Christopher A. Scott ,  Paul Sydlowski ,  John Doyle ,  Ryan A. Amara

IPC: B01L9/00 ,  B01D63/08 ,  B25B5/04 ,  B25B5/08 ,  B25B5/06 ,  B01L3/00 ,  B25B5/14 ,  G01N1/40 ,  B25B7/14

Abstract: A clamp including a first jaw member having a camming surface, a second jaw member pivotable with respect to the first jaw member, a first biasing member biasing the first and second jaw members to a first position; and a locking mechanism that includes a cam or roller for cooperating with the camming surface of the jaw member, and a second biasing member biasing the cam or roller against the camming surface to lock the first and second jaw members in a second position. An optional alignment collar can be used to align components of the filtration apparatus prior to clamping. Filtration apparatus including the clamp, and also optionally including the alignment collar, is also disclosed.