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    Chromatography Apparatus And Method
    1.
    发明申请
    Chromatography Apparatus And Method 有权
    色谱仪和方法

    公开(公告)号：US20140105795A1

    公开(公告)日：2014-04-17

    申请号：US14109988

    申请日：2013-12-18

    申请人： EMD Millipore Corporation

    发明人： Chris Scott ,  Rob Colonna ,  Christopher Barmore ,  Todd Taylor ,  Daniel Morgan

    IPC分类号： B01J20/281

    CPC分类号： G01N1/28 ,  B01D61/18 ,  B01J20/281 ,  B01L3/50255 ,  G01N1/4077 ,  G01N30/14 ,  G01N2030/146

    摘要： Sample preparation device for receiving in sealing relation one or more filter assemblies and one or more sample containers, each container uniquely positioned within the device to receive filtered sample from a designated filter. The device includes a body, a lid disposed on the body, a container tray, a base, an integrated seal on the body, a valve and a valve actuator. The tray can be disposed in a vacuum chamber defined by the lid and the body, and one or more sample containers can be disposed in the tray. When properly positioned in the tray in the vacuum chamber, each container is in fluid communication with a single respective filter assembly disposed in sealing relation in a respective aperture in the lid. A single actuation of a valve to place the vacuum chamber under vacuum causes the lid to seal to the base and drives the simultaneous filtration of a plurality of samples.

    摘要翻译： 用于以密封关系接收一个或多个过滤器组件和一个或多个样品容器的样品制备装置，每个容器唯一地定位在装置内以从指定的过滤器接收经过滤的样品。 该装置包括主体，设置在主体上的盖，容器托盘，基座，主体上的集成密封件，阀和阀致动器。 托盘可以设置在由盖和主体限定的真空室中，并且一个或多个样品容器可以设置在托盘中。 当适当地定位在真空室中的托盘中时，每个容器与在盖中的相应孔中以密封关系设置的单个相应的过滤器组件流体连通。 将真空室置于真空下的阀的单次致动导致盖子密封到基座并驱动多个样品的同时过滤。

    Chromatography apparatus and method
    4.
    发明授权
    Chromatography apparatus and method 有权
    色谱仪和方法

    公开(公告)号：US09429502B2

    公开(公告)日：2016-08-30

    申请号：US14109988

    申请日：2013-12-18

    申请人： EMD Millipore Corporation

    发明人： Chris Scott ,  Rob Colonna ,  Christopher Barmore ,  Todd Taylor ,  Daniel Morgan

    IPC分类号： G01N1/28 ,  G01N1/40 ,  G01N30/14 ,  B01J20/281 ,  B01D61/18 ,  B01L3/00

    CPC分类号： G01N1/28 ,  B01D61/18 ,  B01J20/281 ,  B01L3/50255 ,  G01N1/4077 ,  G01N30/14 ,  G01N2030/146

    摘要： Sample preparation device for receiving in sealing relation one or more filter assemblies and one or more sample containers, each container uniquely positioned within the device to receive filtered sample from a designated filter. The device includes a body, a lid disposed on the body, a container tray, a base, an integrated seal on the body, a valve and a valve actuator. The tray can be disposed in a vacuum chamber defined by the lid and the body, and one or more sample containers can be disposed in the tray. When properly positioned in the tray in the vacuum chamber, each container is in fluid communication with a single respective filter assembly disposed in sealing relation in a respective aperture in the lid. A single actuation of a valve to place the vacuum chamber under vacuum causes the lid to seal to the base and drives the simultaneous filtration of a plurality of samples.

    摘要翻译： 用于以密封关系接收一个或多个过滤器组件和一个或多个样品容器的样品制备装置，每个容器唯一地定位在装置内以从指定的过滤器接收经过滤的样品。 该装置包括主体，设置在主体上的盖，容器托盘，基座，主体上的集成密封件，阀和阀致动器。 托盘可以设置在由盖和主体限定的真空室中，并且一个或多个样品容器可以设置在托盘中。 当适当地定位在真空室中的托盘中时，每个容器与在盖中的相应孔中以密封关系设置的单个相应的过滤器组件流体连通。 将真空室置于真空下的阀的单次致动导致盖子密封到基座并驱动多个样品的同时过滤。

    Immunoassay Product And Process
    5.
    发明申请
    Immunoassay Product And Process 有权
    免疫测定产品和方法

    公开(公告)号：US20160178625A1

    公开(公告)日：2016-06-23

    申请号：US15006153

    申请日：2016-01-26

    申请人： EMD Millipore Corporation

    发明人： Chris Scott ,  Phillip Clark ,  Kurt E. Greenizen ,  Ryan A. Amara ,  Robert Colonna

    IPC分类号： G01N33/558 ,  B01L9/00 ,  B01L3/00

    CPC分类号： G01N33/558 ,  B01J20/28033 ,  B01J20/28035 ,  B01J20/2804 ,  B01L3/5023 ,  B01L9/52 ,  B01L2200/025 ,  B01L2300/0609 ,  B01L2300/0681 ,  B01L2300/069 ,  B01L2300/0809 ,  B01L2300/12 ,  B01L2300/126 ,  B01L2400/0487 ,  B01L2400/049 ,  G01N33/54366 ,  G01N33/56911 ,  G01N2469/10 ,  G01N2469/20

    摘要： The embodiments disclosed herein are directed to an apparatus useful in conducting detection of compounds on blotting membranes. The device is comprised of several layers including a porous support layer below the blotting membrane(s), a flow distributor above the blotting membrane(s) and optionally a well on the flow distributor to contain the liquid to the desired area and to allow for lower starting volumes of such liquid. Preferably, the flow distributor is a non-binding or low binding hydrophilic porous membrane such as a 0.22 micron membrane and the support layer is a grid or sintered porous material. The distributor and support are held together to form an envelope around the membrane(s). The use of a hinge, clips and other such devices is preferred in doing so.

    摘要翻译： 本文公开的实施方案涉及用于在印迹膜上进行化合物检测的装置。 该装置包括多个层，包括印迹膜下面的多孔支撑层，印迹膜上方的流量分布器，以及任选的流量分配器上的孔，以将液体包含到期望的区域并允许 降低这种液体的起始体积。 优选地，流动分配器是非结合或低结合的亲水性多孔膜，例如0.22微米的膜，并且支撑层是格栅或烧结的多孔材料。 分配器和支撑件保持在一起以在膜周围形成一个信封。 在这样做时优选使用铰链，夹子和其它这样的装置。

    Chromatography Apparatus And Method
    6.
    发明申请
    Chromatography Apparatus And Method 有权

    公开(公告)号：US20140298924A1

    公开(公告)日：2014-10-09

    申请号：US14309051

    申请日：2014-06-19

    申请人： EMD Millipore Corporation

    发明人： Chris Scott ,  Rob Colonna ,  Christopher Barmore ,  Todd Taylor ,  Daniel Morgan

    IPC分类号： G01N1/28

    CPC分类号： G01N1/28 ,  B01D61/18 ,  B01J20/281 ,  B01L3/50255 ,  G01N1/4077 ,  G01N30/14 ,  G01N2030/146

    摘要： Sample preparation device for receiving in sealing relation one or more filter assemblies and one or more sample containers, each container uniquely positioned within the device to receive filtered sample from a designated filter. The device includes a body, a lid disposed on the body, a container tray, a base, an integrated seal on the body, a valve and a valve actuator. The tray can be disposed in a vacuum chamber defined by the lid and the body, and one or more sample containers can be disposed in the tray. When properly positioned in the tray in the vacuum chamber, each container is in fluid communication with a single respective filter assembly disposed in sealing relation in a respective aperture in the lid. A single actuation of a valve to place the vacuum chamber under vacuum causes the lid to seal to the base and drives the simultaneous filtration of a plurality of samples.

    Chromatography apparatus and method
    7.
    发明授权
    Chromatography apparatus and method 有权
    色谱仪和方法

    公开(公告)号：US09594007B2

    公开(公告)日：2017-03-14

    申请号：US14309051

    申请日：2014-06-19

    申请人： EMD Millipore Corporation

    发明人： Chris Scott ,  Rob Colonna ,  Christopher Barmore ,  Todd Taylor ,  Daniel Morgan

    IPC分类号： G01N1/28 ,  G01N1/40 ,  G01N30/14 ,  B01J20/281 ,  B01D61/18 ,  B01L3/00

    CPC分类号： G01N1/28 ,  B01D61/18 ,  B01J20/281 ,  B01L3/50255 ,  G01N1/4077 ,  G01N30/14 ,  G01N2030/146

    摘要： Sample preparation device for receiving in sealing relation one or more filter assemblies and one or more sample containers, each container uniquely positioned within the device to receive filtered sample from a designated filter. The device includes a body, a lid disposed on the body, a container tray, a base, an integrated seal on the body, a valve and a valve actuator. The tray can be disposed in a vacuum chamber defined by the lid and the body, and one or more sample containers can be disposed in the tray. When properly positioned in the tray in the vacuum chamber, each container is in fluid communication with a single respective filter assembly disposed in sealing relation in a respective aperture in the lid. A single actuation of a valve to place the vacuum chamber under vacuum causes the lid to seal to the base and drives the simultaneous filtration of a plurality of samples.

    摘要翻译： 用于以密封关系接收一个或多个过滤器组件和一个或多个样品容器的样品制备装置，每个容器唯一地定位在装置内以从指定的过滤器接收经过滤的样品。 该装置包括主体，设置在主体上的盖，容器托盘，基座，主体上的集成密封件，阀和阀致动器。 托盘可以设置在由盖和主体限定的真空室中，并且一个或多个样品容器可以设置在托盘中。 当适当地定位在真空室中的托盘中时，每个容器与在盖中的相应孔中以密封关系设置的单个相应的过滤器组件流体连通。 将真空室置于真空下的阀的单次致动导致盖子密封到基座并驱动多个样品的同时过滤。

    IHC, Tissue Slide Fluid Exchange Disposable And System
    9.
    发明申请
    IHC, Tissue Slide Fluid Exchange Disposable And System 审中-公开
    IHC，组织滑动液体交换一次性和系统

    公开(公告)号：US20150260621A1

    公开(公告)日：2015-09-17

    申请号：US14618007

    申请日：2015-02-10

    申请人： EMD Millipore Corporation

    发明人： Chris Scott ,  Paul Sydlowski ,  John Doyle ,  Ryan Amara ,  Libby Kellard ,  Sara Gutierrez ,  Marc Emerick

    IPC分类号： G01N1/31

    摘要： Apparatus and method for Immunohistochemistry, including a slide holder assembly fixture, a slide holder, a slide holder frame, and a slide holder frame assembly adapted to be placed in communication with a driving force to draw fluid through the slide holder. The slide holder may include an injection port that allows consistent fluid delivery and recovery, while minimizing the introduction of air bubbles. The slide holder may include a reservoir that allows for filling, soaking, rinsing, flushing, uniform antibody coverage of the tissue and reduces handling time, space, and errors, and one or more sample chambers. The slide orientation in the slide holder allows for visualization of label information and tissue to confirm adequate antibody coverage. A multi-port frame allows multiple assays to be carried out concurrently, and is removable from a vacuum manifold and allows for easy transport from the vacuum manifold to an incubator/refrigerator and back.

    摘要翻译： 用于免疫组织化学的装置和方法，包括滑动支架组件夹具，滑动支架，滑动支架框架和滑动支架框架组件，其适于与驱动力连通以将流体通过滑块保持器拉动。 滑动架可以包括一个注射口，其允许一致的流体输送和回收，同时最小化气泡的引入。 载玻片保持器可以包括允许填充，浸泡，漂洗，冲洗，组织的均匀抗体覆盖并减少处理时间，空间和错误以及一个或多个样品室的储存器。 幻灯片固定器中的滑动方向允许标记信息和组织的可视化，以确认足够的抗体覆盖。 多端口框架允许多个测定同时进行，并且可从真空歧管移除，并且允许从真空歧管到培养箱/冰箱和背部的容易运输。