公开(公告)号：US20230332141A1

公开(公告)日：2023-10-19

申请号：US18173821

申请日：2023-02-24

Applicant: EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUNDATION

Inventor： Hyunbo SHIM ,  Xuelian BAI ,  Moonseon JANG

IPC: C12N15/10 ,  C07K16/00

CPC classification number: C12N15/1089 ,  C07K16/005 ,  C07K2317/565 ,  C07K2317/567

Abstract: The present disclosure relates to a novel method of preparing an antibody library and the prepared library therefrom. The antibody library prepared by the preparation method according to an embodiment of the present disclosure contains antibodies having excellent physical properties to a large number of antigens, and thus can be favorably used as an antibody library that has functional diversity, contains a variety of unique sequences, and also has improved amplification efficiency after panning.

公开(公告)号：US20170362306A1

公开(公告)日：2017-12-21

申请号：US15648137

申请日：2017-07-12

Applicant: EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUNDATION ,  Medicinal Bioconvergence Research Center

Inventor： Hyun Bo SHIM ,  Ji Hye KIM ,  Xuelian BAI

IPC: C07K16/00 ,  C12N15/10

CPC classification number: C07K16/005 ,  C07K16/00 ,  C07K2317/21 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/567 ,  C07K2317/622 ,  C12N15/1037 ,  C40B40/10 ,  G16B35/00 ,  G16C20/60

Abstract: The present invention relates to a method for preparing a novel antibody library and a library prepared thereby. The antibody library prepared according to the present invention contains antibodies having excellent physical properties against a plurality of antigens, thereby having functional diversity and containing a plurality of unique sequences, and thus can be favorably used as an antibody library.