公开(公告)号：US20070184511A1

公开(公告)日：2007-08-09

申请号：US11561878

申请日：2006-11-20

申请人： Kevin Dawson ,  Wasyl Malyj ,  William Haddon ,  Daniel Tuse ,  Earl White ,  Driss Zoukhri ,  Ian Rawe

发明人： Kevin Dawson ,  Wasyl Malyj ,  William Haddon ,  Daniel Tuse ,  Earl White ,  Driss Zoukhri ,  Ian Rawe

IPC分类号： C12Q1/37 ,  G06F19/00

CPC分类号： G01N33/6848 ,  G16H10/20 ,  G16H50/70

摘要： Described is a method for diagnosing a person having or being at risk of developing Sjögren's Syndrome and excluding patients with symptoms similar to Sjögren's Syndrome but with a different etiology, comprising the following steps: providing a sample of a body fluid or tissue from said person, said sample containing a mixture of unknown proteins, protein fragments or peptides; analyzing said samples with mass spectrometry to generate a m/z (mass to charge ratio) spectrogram for each sample; comparing whether the patient's sample contains m/z values that are characteristic of a Sjögren's Syndrome reference database derived from the analysis and cataloguing of multiple patient spectrograms; and determining whether said patient either has or does not have Sjögren's Syndrome on the basis of this comparative analysis.

摘要翻译： 描述了一种用于诊断患有或有发展Sjögren综合征风险的人的方法，并排除具有与Sjögren综合征相似但具有不同病因的症状的患者，其包括以下步骤：从所述人提供体液或组织的样品， 所述样品含有未知蛋白质，蛋白质片段或肽的混合物; 通过质谱分析所述样品以产生每个样品的m / z（质荷比）谱图; 比较患者样本是否包含源自多个患者谱图分析和编目的Sjögren综合征参考数据库特征的m / z值; 并且基于该比较分析确定所述患者是否具有或不具有Sjögren综合征。

公开(公告)号：US20070249000A1

公开(公告)日：2007-10-25

申请号：US11740272

申请日：2007-04-25

申请人： Daniel Tuse ,  Kevin Dawson ,  William Haddon ,  Earl White ,  Wasyl Malyj

发明人： Daniel Tuse ,  Kevin Dawson ,  William Haddon ,  Earl White ,  Wasyl Malyj

IPC分类号： G01N33/574 ,  G01N33/50

CPC分类号： G01N33/57407

摘要： Described is a method for diagnosing a person having or being at risk of developing certain B-cell pathologies, including Sjögren's Syndrome and non-Hodgkin's lymphoma, and excluding patients with symptoms similar to Sjögren's Syndrome but with a different etiology, comprising the following steps: providing a sample of a body fluid or tissue from said person, said sample containing a mixture of unknown proteins, protein fragments or peptides; analyzing said samples with mass spectrometry to generate a m/z (mass to charge ratio) spectrogram for each sample; comparing whether the patient's sample contains m/z values that are characteristic of a Sjögren's Syndrome reference database derived from the analysis and cataloguing of multiple patient spectrograms; and determining whether said patient either has or does not have Sjögren's Syndrome on the basis of this comparative analysis.

摘要翻译： 描述了一种用于诊断具有或具有发展某些B细胞病变的风险的人的方法，包括Sjögren综合征和非霍奇金淋巴瘤，并且排除具有与Sjögren综合征相似但具有不同病因的患者，包括以下步骤： 提供来自所述人的体液或组织的样品，所述样品含有未知蛋白质，蛋白质片段或肽的混合物; 通过质谱分析所述样品以产生每个样品的m / z（质荷比）谱图; 比较患者样本是否包含源自多个患者谱图分析和编目的Sjögren综合征参考数据库特征的m / z值; 并且基于该比较分析确定所述患者是否具有或不具有Sjögren综合征。

公开(公告)号：US20050172596A1

公开(公告)日：2005-08-11

申请号：US10924561

申请日：2004-08-24

申请人： Earl White

发明人： Earl White

IPC分类号： A01D34/86 ,  A01D34/43

CPC分类号： A01D34/866

摘要： The new art to which this application pertains is an electrically operated boom, of various overall lengths, to extend a small rotary blade electric grass cutter from a nominal 5 to 20 feet down, or out, to cut grass on steep slopes and in ditches. It is a fully mechanized electric grass cutting machine for cutting grass where it is difficult, impossible, or unsafe to stand up. It is an electric, rotary blade, grass cutting-head on the end of a three-section electrically powered telescoping boom, mounted on a powered carrier vehicle; such as, a small riding mower. The carrier vehicle is not a part of this application. It can be operated by persons of limited strength, physical abilities or aptitudes. It is controlled with two electric switches and one hand crank. Complete machine and carrier are inexpensive; less than the cost of a small riding mower. It is a machine for average people who are not skilled in machine operation; and for residential use.

摘要翻译： 本应用所涉及的新技术是具有各种总长度的电动起重臂，将小型旋转刀片电动割草机从标称的5至20英尺向下或向外延伸，以在陡峭的斜坡和沟渠上切割草。 它是一种完全机械化的电动草坪切割机，用于切割难以站立的困难，不可能或不安全的草地。 它是一个电动旋转叶片，草切割头，在三段电动伸缩臂的末端，安装在动力运载工具上; 如小型割草机。 承运人车辆不属于本申请的一部分。 它可以由有限的力量，身体能力或能力的人操作。 它由两个电动开关和一个手动曲柄控制。 完整的机器和载体便宜; 少于小型割草机的成本。 对于机器操作不熟练的普通人来说，这是一台机器; 并用于住宅用途。