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公开(公告)号：US5882302A
公开(公告)日：1999-03-16
申请号：US669601
申请日：1996-06-24
CPC分类号： A61B8/06 , A61B5/416 , A61B8/08 , A61B8/12 , A61B8/445 , A61B8/4461 , A61B8/461 , A61B8/467 , A61B8/483 , A61B8/485 , A61N7/022 , A61B2017/00274 , A61B2017/12004 , A61B2018/00547 , A61B2090/378 , A61B8/4281 , A61B8/4405 , A61N2007/0065 , A61N2007/0078
摘要： Methods and apparatus for the remote coagulation of blood using high-intensity focused ultrasound (HIFU) are provided. A remote hemostasis method comprises identifying a site of internal bleeding and focusing therapeutic ultrasound energy on the site, the energy being focused through an intervening tissue. An apparatus for producing remote hemostasis comprises a focused therapeutic ultrasound radiating surface and a sensor for identifying a site of internal bleeding, with a registration means coupled to the radiating surface and the sensor top bring a focal target and the bleeding site into alignment. The sensor generally comprises a Doppler imaging display. Hemostasis enhancing agents may be introduced to the site for actuation by the ultrasound energy.
摘要翻译： 提供了使用高强度聚焦超声（HIFU）进行血液远程凝血的方法和装置。 远程止血方法包括识别内部出血部位并将治疗超声能量聚焦在部位上，能量通过中间组织聚焦。 用于产生远端止血的装置包括聚焦的治疗超声辐射表面和用于识别内部出血部位的传感器，其中联接到辐射表面的对准装置和传感器顶部使焦点瞄准器和出血部位对准。 传感器通常包括多普勒成像显示器。 可以将止血增强剂引入该部位以通过超声能量致动。
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公开(公告)号：US5993389A
公开(公告)日：1999-11-30
申请号：US562280
申请日：1995-11-22
CPC分类号： A61B8/06 , A61B5/416 , A61B8/08 , A61B8/12 , A61B8/445 , A61B8/4461 , A61B8/461 , A61B8/467 , A61B8/483 , A61B8/485 , A61N7/022 , A61B2017/00274 , A61B2017/12004 , A61B2018/00547 , A61B2090/378 , A61B8/4281 , A61B8/4405 , A61N2007/0065 , A61N2007/0078
摘要： Methods and apparatus for the remote coagulation of blood using high-intensity focused ultrasound (HIFU) are provided. A remote hemostasis method comprises identifying a site of internal bleeding and focusing therapeutic ultrasound energy on the site, the energy being focused through an intervening tissue. An apparatus for producing remote hemostasis comprises a focused therapeutic ultrasound radiating surface and a sensor for identifying a site of internal bleeding, with a registration means coupled to the radiating surface and the sensor to bring a focal target and the bleeding site into alignment. The sensor generally comprises a Doppler imaging display. Hemostasis enhancing agents may be introduced to the site for actuation by the ultrasound energy.
摘要翻译： 提供了使用高强度聚焦超声（HIFU）进行血液远程凝血的方法和装置。 远程止血方法包括识别内部出血部位并将治疗超声能量聚焦在部位上，能量通过中间组织聚焦。 用于产生远端止血的装置包括聚焦的治疗超声波辐射表面和用于识别内部出血部位的传感器，其中配准装置联接到辐射表面和传感器以使焦点靶点和出血部位对齐。 传感器通常包括多普勒成像显示器。 可以将止血增强剂引入该部位以通过超声能量致动。
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公开(公告)号：US6083159A
公开(公告)日：2000-07-04
申请号：US325885
申请日：1999-06-04
申请人： Edward C. Driscoll, Jr. , Larry Crum , Wing K. Law , Stan DeMarta
发明人： Edward C. Driscoll, Jr. , Larry Crum , Wing K. Law , Stan DeMarta
CPC分类号： A61B8/06 , A61B5/416 , A61B8/08 , A61B8/12 , A61B8/445 , A61B8/4461 , A61B8/461 , A61B8/467 , A61B8/483 , A61B8/485 , A61N7/022 , A61B2017/00274 , A61B2017/12004 , A61B2018/00547 , A61B2090/378 , A61B8/4281 , A61B8/4405 , A61N2007/0065 , A61N2007/0078
摘要： Methods and apparatus for the remote coagulation of blood using high-intensity focused ultrasound (HIFU) are provided. A remote hemostasis method comprises identifying a site of internal bleeding and focusing therapeutic ultrasound energy on the site, the energy being focused through an intervening tissue. An apparatus for producing remote hemostasis comprises a focused therapeutic ultrasound radiating surface and a sensor for identifying a site of internal bleeding, with a registration means coupled to the radiating surface and the sensor to bring a focal target and the bleeding site into alignment. The sensor generally comprises a Doppler imaging display. Hemostasis enhancing agents may be introduced to the site for actuation by the ultrasound energy.
摘要翻译： 提供了使用高强度聚焦超声（HIFU）进行血液远程凝血的方法和装置。 远程止血方法包括识别内部出血部位并将治疗超声能量聚焦在部位上，能量通过中间组织聚焦。 用于产生远端止血的装置包括聚焦的治疗超声波辐射表面和用于识别内部出血部位的传感器，其中配准装置联接到辐射表面和传感器以使焦点靶点和出血部位对齐。 传感器通常包括多普勒成像显示器。 可以将止血增强剂引入该部位以通过超声能量致动。
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4.发明授权
公开(公告)号：US5762066A
公开(公告)日：1998-06-09
申请号：US446503
申请日：1995-05-22
申请人： Wing K. Law , Carl Hennige , Frank Fry , Narendra T. Sanghvi , Fred Miller , Paul Kendrick , Stan DeMarta
发明人： Wing K. Law , Carl Hennige , Frank Fry , Narendra T. Sanghvi , Fred Miller , Paul Kendrick , Stan DeMarta
CPC分类号： A61B8/12 , A61B8/06 , A61B8/08 , A61B8/445 , A61B8/4461 , A61B8/483 , A61B8/485 , A61N7/022 , A61B2017/00274 , A61B2018/00547 , A61B8/4281 , A61B8/4405 , A61B8/461 , A61B8/467 , A61N2007/0065 , A61N2007/0078
摘要： A High Intensity Focused Ultrasound system is provided for treatment of focal disease. The preferred embodiment includes an intracavity probe having two active ultrasound radiating surfaces with different focal geometries. Selectively energizing the first surface focuses therapeutic energy a first distance from the housing, energizing the second surface focuses therapeutic energy nearer the housing. Preferably, the probe includes a thin, flexible, inelastic membrane which is rigidized with pressure to allow blunt manipulation of tissue. Methods of use of the probe are also provided, particularly for treatment of diseases of the prostate.
摘要翻译： 提供高强度聚焦超声系统用于治疗局灶性疾病。 优选实施例包括具有不同焦点几何形状的两个有源超声辐射表面的腔内探针。 选择性地激励第一表面将治疗能量聚焦在距离壳体的第一距离处，使第二表面通电使得靠近壳体的治疗能量聚焦。 优选地，探针包括薄的，柔性的非弹性膜，其在压力下被硬化以允许组织的钝化操作。 还提供了探针的使用方法，特别是用于治疗前列腺疾病。
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公开(公告)号：US5520188A
公开(公告)日：1996-05-28
申请号：US333471
申请日：1994-11-02
CPC分类号： A61B8/4483 , A61B8/0833 , A61N7/02 , B06B1/0625 , G01S15/8922 , G10K11/346 , A61B2017/22028 , A61B2090/378 , A61N2007/0052
摘要： A transducer for use in a localization and therapeutic ultrasound system. The transducer of the present invention includes multiple elements that are driven separately. The elements operate together to focus a continuous wave ultrasound beam at a focal zone that is at a variable distance from the elements. The transducer includes a mechanism to adjust the focal distance so that the focal zone may be moved to multiple depths.
摘要翻译： 用于定位和治疗超声系统的换能器。 本发明的换能器包括分开驱动的多个元件。 这些元件一起操作以将连续波超声波束聚焦在距离元件可变距离的聚焦区域。 换能器包括调节焦距的机构，使得焦点区域可以移动到多个深度。
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