公开(公告)号：US20250143898A1

公开(公告)日：2025-05-08

申请号：US19016134

申请日：2025-01-10

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Eran Grosu ,  Tal Reich ,  Yuval Kasher ,  Roei Mayo ,  Ben Shitrit ,  Nikolai Gurovich ,  Emil Karapetian ,  Arvin T. Chang ,  Scott Louis Pool ,  Leonardo Paim Nicolau Da Costa ,  Michael G. Valdez

IPC: A61F2/86 ,  A61F2/95

Abstract: An implant for adding compliance to a blood vessel includes a first elongate rail shaped to contact an inner wall of a blood vessel and a second elongate rail shaped to contact an opposing inner wall of the blood vessel. Connectors extend between the first and second rails for providing a separation therebetween and maintaining the rails at locations on opposing sides of the lumen after implantation. The connectors push the rails outwardly for biasing the blood vessel toward a substantially oval shape. The connectors are preferably flexible for allowing the blood vessel to change shape during use for adding compliance to the blood vessel. The elongate rails are preferably curved or hemi-spherical for conforming to the shape of the inner wall of the blood vessel.

公开(公告)号：US20250099239A1

公开(公告)日：2025-03-27

申请号：US18969878

申请日：2024-12-05

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Anatoly Dvorsky ,  Eran Grosu ,  Ilan Leshecz ,  Michael Bukin ,  Nikolai Gurovich ,  Assaf Sharon ,  David Maimon

IPC: A61F2/24

Abstract: Prosthetic valves that include support arms extending from support posts thereof, and methods for utilizing such prosthetic valves, are disclosed herein. As one example, a prosthetic valve can include an annular frame movable between a radially compressed state and a radially expanded state, and at least one support arm. The frame can include a plurality of support posts, each extending between a post inflow end and an opposite post outflow end. The support arm can extend from a corresponding support post, and terminate at a free-ended tip which is biased radially away from the corresponding support post.

公开(公告)号：US20250090312A1

公开(公告)日：2025-03-20

申请号：US18961277

申请日：2024-11-26

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： David Maimon ,  Tamir S. Levi ,  Nikolai Gurovich ,  Karin Lavon ,  Martyn Rhys Thomas

IPC: A61F2/24

Abstract: The present disclosure relates to prosthetic valves that include information indicators which can indicate suitable information associated with a previously implanted prosthetic valve. Such information indicators can be internally formed in relatively wide support posts of mechanically expandable prosthetic valve, or can be externally formed along support posts of mechanically expandable prosthetic valve or vertical struts of balloon expandable prosthetic valves.

公开(公告)号：US20240277473A1

公开(公告)日：2024-08-22

申请号：US18645284

申请日：2024-04-24

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Michael Bukin ,  Nikolai Gurovich ,  Anatoly Dvorsky ,  Eran Grosu ,  Noam Nir ,  Joseph Mordechai Leichner

IPC: A61F2/24

CPC classification number: A61F2/243 ,  A61F2/2418 ,  A61F2250/001

Abstract: A prosthetic device, such as a prosthetic heart valve, can include a radially compressible and expandable frame and a screw actuator that is coupled to the frame and configured to be rotated to radially expand the frame from a radially compressed state to a first radially expanded state. The frame includes an over-expansion structure that is configured to allow relative sliding movement between the screw actuator and the frame in a longitudinal direction to permit the frame to radially expand from the first radially expanded state to a second radially expanded state when an external expansion force applied to the prosthetic heart valve exceeds a predetermined force.

公开(公告)号：US20230149162A1

公开(公告)日：2023-05-18

申请号：US18157044

申请日：2023-01-19

Applicant: Edwards Lifesciences Corporation

Inventor： Nikolai Gurovich ,  Tamir S. Levi

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2230/0069

Abstract: An implantable prosthetic device can include a frame movable between a radially compressed configuration and a radially expanded configuration, and a valvular structure. The frame can have an inflow orifice, an outflow orifice, and one or more commissure windows. The valvular structure can include a plurality of leaflets, each leaflet having a main body with an inflow edge, an outflow edge, and a pair of opposing tabs. Each tab can be paired with an adjacent tab of an adjacent leaflet to form a commissure tab assembly, and each commissure tab assembly being coupled to a respective commissure window. Each tab can extend from the main body at an angle such that a radially outer edge of the tab corresponds to a draft angle of the frame.

公开(公告)号：US20230143332A1

公开(公告)日：2023-05-11

申请号：US18095440

申请日：2023-01-10

Applicant: Edwards Lifesciences Corporation

Inventor： Tamir S. Levi ,  Nikolai Gurovich ,  Elena Sherman ,  Ziv Yohanan

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2220/0075 ,  A61F2220/0091

Abstract: The present invention relates to implantable prosthetic devices, such as prosthetic heart valves, and to attachment configurations and methods of attaching soft components, such as leaflets or skirts, to frames of such prosthetic valves.

公开(公告)号：US20250064584A1

公开(公告)日：2025-02-27

申请号：US18942285

申请日：2024-11-08

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Michael Bukin ,  Nikolai Gurovich ,  Elena Sherman ,  Anatoly Dvorsky ,  Giolnara Pinhas

IPC: A61F2/24

Abstract: A prosthetic heart valve can include a radially expandable and compressible annular frame, a valvular structure, and a commissure cover. The frame can include a plurality of struts defining the annular frame, and a plurality of commissure support structures each defining a commissure opening positioned along a circumference of the annular frame. The valvular structure can be mounted within the frame, the valvular structure including a plurality of commissures each extending radially through a respective commissure opening to attach the valvular structure to the frame, each commissure having an outflow edge that extends from a radial outer surface of the frame. The commissure cover can be disposed at least partially over the outflow edge of the commissure and can define a ramped surface that extends from the radial outer surface of the frame to a radial outer surface of the commissure.

公开(公告)号：US20240374384A1

公开(公告)日：2024-11-14

申请号：US18780203

申请日：2024-07-22

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Anatoly Dvorsky ,  Nikolai Gurovich ,  Michael Bukin ,  Eran Grosu

IPC: A61F2/24

Abstract: A prosthetic heart valve can include a radially expandable and compressible frame and a valvular structure. The frame can include a plurality of circumferentially spaced axial struts, a plurality of pairs of axial posts, and a plurality of rows of angled struts. Each pair of axial posts can be positioned circumferentially between two axial struts. The plurality of rows can include at least a first row, a second row downstream of the first row, a third row downstream of the second row, and a fourth row downstream of the third row. Each of the angled struts can be connected at one end to one of the axial struts and at another end to one of the axial posts. The angled struts of the first and fourth rows can be shorter than the struts of the second and third rows.

公开(公告)号：US20240366367A1

公开(公告)日：2024-11-07

申请号：US18772519

申请日：2024-07-15

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Anatoly Dvorsky ,  Alon Ben-Yosef ,  Eran Grosu ,  Nikolai Gurovich ,  Michael Bukin ,  Ilan Leshecz ,  Joseph Mordechai Leichner

IPC: A61F2/24

Abstract: This disclosure is directed to prosthetic heart valves and frames for prosthetic heart valves having actuation assemblies with at least two bolts coupled to each other. The actuation assembly with at least two bolts allow different portions of the actuation assembly to be designed to meet different needs. In one example, the actuation mechanism can include a first bolt coupled end-to-end with a second bolt. The second bolt can have a greater diameter and correspondingly greater mechanical strength than the first bolt. The first bolt can have a lesser diameter suitable for minimizing the thickness of surrounding and adjacent valve frame components. The actuation assembly can also include one or more of a nut, a washer, and a portion designed to attach to components of a delivery system. Also disclosed herein are actuation assemblies including a washer secured by a pin extending through the bolt of the actuation assembly.

公开(公告)号：US12029644B2

公开(公告)日：2024-07-09

申请号：US16937964

申请日：2020-07-24

Applicant: Edwards Lifesciences Corporation

Inventor： Nikolai Gurovich ,  Alexey Tsypenyuk

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/2409 ,  A61F2/2433 ,  A61F2230/001 ,  A61F2230/006 ,  A61F2250/0039

Abstract: A prosthetic heart valve includes a frame having an inflow end, an outflow end, and a central portion. The frame is radially expandable from a collapsed configuration to an expanded configuration. The inflow end includes a plurality of first strut members having a first strut width and forming a first angle between adjacent first strut members, and the central portion includes a plurality of second strut members having a second strut width and forming a second angle between adjacent second strut members. A plurality of leaflets are positioned within the frame. At least one of the first angle and the second angle, or the first strut width and the second strut width, are different such that when the prosthetic heart valve is crimped onto a cylindrical balloon and expanded using the cylindrical balloon, a diameter of the outflow end is different from a diameter of the central portion.