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公开(公告)号：US10941148B2
公开(公告)日：2021-03-09
申请号：US16391882
申请日：2019-04-23
Applicant: Eisai R&D Management Co., Ltd.
Inventor： Wanjun Zheng , Xiaojie Zhu , Hong Du , Maarten Postema , Yimin Jiang , Jing Li , Robert Yu , Hyeong-wook Choi , Jaemoon Lee , Frank Fang , Daniel Custar
IPC: C07D487/04 , C07D519/00 , A61P35/00
Abstract: We provide compounds given by Formula I, which is shown in FIG. 3, or pharmaceutically acceptable salts thereof, as well as formulations thereof and methods of use of those compounds and formulations for treatment of cancer.
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公开(公告)号：US20180305362A1
公开(公告)日：2018-10-25
申请号：US15768668
申请日：2016-10-14
Applicant: Eisai R&D Management Co., Ltd.
Inventor： Wanjun Zheng , Xiaojie Zhu , Hong Du , Maarten Postema , Yimin Jiang , Jing Li , Robert Yu , Hyeong-wook Choi , Jaemoon Lee , Frank Fang , Daniel Custar
IPC: C07D487/04 , C07D519/00 , A61P35/00
CPC classification number: C07D487/04 , A61P35/00 , C07D519/00
Abstract: We provide compounds given by Formula I, which is shown in FIG. 3, or pharmaceutically acceptable salts thereof, as well as formulations thereof and methods of use of those compounds and formulations for treatment of cancer.
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公开(公告)号：US12251394B2
公开(公告)日：2025-03-18
申请号：US17058817
申请日：2019-05-31
Applicant: Eisai R&D Management Co., Ltd.
Inventor： Dae-Shik Kim , Frank Fang , Atsushi Endo , Hyeong-Wook Choi , Ming-Hong Hao , Xingfeng Bao , Kuan-Chun Huang
IPC: A61K31/7084 , A61P35/04
Abstract: Provided herein are methods for the treatment of bladder cancer.
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Patent Agency Ranking
公开(公告)号：US20190315754A1
公开(公告)日：2019-10-17
申请号：US16391882
申请日：2019-04-23
Applicant: Eisai R&D Management Co., Ltd.
Inventor： Wanjun Zheng , Xiaojie Zhu , Hong Du , Maarten Postema , Yimin Jiang , Jing Li , Robert Yu , Hyeong-wook Choi , Jaemoon Lee , Frank Fang , Daniel Custar
IPC: C07D487/04 , C07D519/00 , A61P35/00
Abstract: We provide compounds given by Formula I, which is shown in FIG. 3, or pharmaceutically acceptable salts thereof, as well as formulations thereof and methods of use of those compounds and formulations for treatment of cancer.
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公开(公告)号：US20150065503A1
公开(公告)日：2015-03-05
申请号：US14394431
申请日：2013-04-11
Applicant: EPIZYME, INC. , EISAI R&D MANAGEMENT CO., LTD.
Inventor： Kevin Wayne Kuntz , Kuan-chun Huang , Hyeong wook Choi , Kristen Sanders , Steven Mathieu , Arani Chanda , Frank Fang
IPC: C07D405/12
CPC classification number: A61K31/5377 , C07D405/12
Abstract: Provided herein is N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-4-methyl-4′-(morpholinomethyl)-[1,1′-biphenyl]-3-carboxamide hydrobromide. Also provided herein is a particular polymorph form of this compound.
Abstract translation: 本文提供的是N - （（4,6-二甲基-2-氧代-1,2-二氢吡啶-3-基）甲基）-5-（乙基（四氢-2H-吡喃-4-基）氨基）-4- 甲基-4' - （吗啉代甲基） - [1,1'-联苯] -3-甲酰胺氢溴酸盐。 本文还提供了该化合物的特定多晶型物。
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公开(公告)号：US10316040B2
公开(公告)日：2019-06-11
申请号：US15768668
申请日：2016-10-14
Applicant: Eisai R&D Management Co., Ltd.
Inventor： Wanjun Zheng , Xiaojie Zhu , Hong Du , Maarten Postema , Yimin Jiang , Jing Li , Robert Yu , Hyeong-wook Choi , Jaemoon Lee , Frank Fang , Daniel Custar
IPC: C07D487/04 , C07D519/00 , A61P35/00
Abstract: We provide compounds given by Formula I, which is shown in FIG. 3, or pharmaceutically acceptable salts thereof, as well as formulations thereof and methods of use of those compounds and formulations for treatment of cancer.
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公开(公告)号：US11339188B2
公开(公告)日：2022-05-24
申请号：US16781352
申请日：2020-02-04
Applicant: Eisai R&D Management Co., Ltd.
Inventor： Dae-Shik Kim , Frank Fang , Atsushi Endo , Hyeong-wook Choi , Ming-Hong Hao , Xingfeng Bao , Kuan-Chun Huang
IPC: C07H21/02 , A61P35/02 , A61K31/7084 , C07F9/6587 , C07H21/00 , A61P31/04 , A61P37/04
Abstract: Provided herein are compounds useful for the treatment of cancer.
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公开(公告)号：US10246480B2
公开(公告)日：2019-04-02
申请号：US15898533
申请日：2018-02-17
Applicant: Eisai R&D Management Co., Ltd.
Inventor： Dae-Shik Kim , Frank Fang , Atsushi Endo , Hyeong-Wook Choi , Ming-Hong Hao , Xingfeng Bao , Kuan-Chun Huang
IPC: C07H21/02 , A61P35/02 , A61K31/7084 , C07F9/6587 , C07H21/00 , A61P31/04 , A61P37/04
Abstract: Provided herein are compounds useful for the treatment of cancer.
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