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公开(公告)号:US07521195B1
公开(公告)日:2009-04-21
申请号:US11490329
申请日:2006-07-21
申请人: Elizabeth Joseloff , Aiqun Li , Tao He , Steve Ruben
发明人: Elizabeth Joseloff , Aiqun Li , Tao He , Steve Ruben
IPC分类号: G01N33/53
CPC分类号: G01N33/57423 , G01N2500/04 , Y10T436/143333
摘要: The present invention provides a method for diagnosing and detecting diseases associated with lung. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in lung diseases (LCAT) and antibodies binds to LCATs. The present invention provides that LCATs are used as targets for screening agents that modulates the LCAT activities. Further the present invention provides methods for treating diseases associated with lung.
摘要翻译: 本发明提供了诊断和检测与肺相关疾病的方法。 本发明提供在肺部疾病(LCAT)中差异表达的一种或多种蛋白质或其片段,肽或核酸分子,并且抗体结合LCAT。 本发明提供LCAT作为调节LCAT活性的筛选剂的靶标。 此外,本发明提供了治疗与肺相关疾病的方法。
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公开(公告)号:US07807392B1
公开(公告)日:2010-10-05
申请号:US11905216
申请日:2007-09-28
申请人: Bruno Domon , Elizabeth Joseloff , Aiqun Li , Tao He
发明人: Bruno Domon , Elizabeth Joseloff , Aiqun Li , Tao He
IPC分类号: G01N33/574
CPC分类号: G01N33/57423
摘要: The present invention provides a method for diagnosing and detecting diseases associated with lung. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in lung cancer (LCAT) and antibodies binds to LCATs. The present invention provides that LCATs are used as targets for screening agents that modulates the LCAT activities. Further the present invention provides methods for treating diseases associated with lung.
摘要翻译: 本发明提供了诊断和检测与肺相关疾病的方法。 本发明提供在肺癌(LCAT)中差异表达的一种或多种蛋白质或其片段,肽或核酸分子,并且抗体结合LCAT。 本发明提供LCAT作为调节LCAT活性的筛选剂的靶标。 此外,本发明提供了治疗与肺相关疾病的方法。
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公开(公告)号:US07998689B2
公开(公告)日:2011-08-16
申请号:US12557303
申请日:2009-09-10
申请人: Elizabeth Joseloff , Steve Ruben , Tao He , Yeounjin Kim
发明人: Elizabeth Joseloff , Steve Ruben , Tao He , Yeounjin Kim
IPC分类号: G01N33/53 , G01N33/574 , C12Q1/68
CPC分类号: C07K14/47 , A61K2039/505 , C07K14/435 , C07K16/18 , C07K16/3038 , C07K2317/622 , C07K2317/73 , C07K2317/732 , C07K2317/734 , C07K2317/92 , C12N15/113 , C12N2310/14 , C12Q1/6876 , C12Q1/6886 , C12Q2600/118 , C12Q2600/136 , C12Q2600/158 , G01N33/53 , G01N33/57438 , G01N33/57484 , G01N2333/47 , G01N2500/00 , G01N2500/10 , Y10T436/143333
摘要: The present invention provides a method for diagnosing and detecting diseases associated with kidney. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in kidney diseases (KCAT) and antibodies binds to KCATs. The present invention provides that KCATs are used as targets for screening agents that modulates the KCAT activities. Further the present invention provides methods for treating diseases associated with kidney.
摘要翻译: 本发明提供了诊断和检测与肾相关的疾病的方法。 本发明提供在肾脏疾病(KCAT)中差异表达的一种或多种蛋白质或其片段,肽或核酸分子,并且抗体结合KCAT。 本发明提供KCAT作为调节KCAT活性的筛选剂的靶标。 此外,本发明提供了治疗与肾相关的疾病的方法。
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公开(公告)号:US07608413B1
公开(公告)日:2009-10-27
申请号:US11878050
申请日:2007-07-20
申请人: Elizabeth Joseloff , Steve Ruben , Tao He , Yeoun Jim Kim
发明人: Elizabeth Joseloff , Steve Ruben , Tao He , Yeoun Jim Kim
IPC分类号: G01N33/574 , A61K39/395 , A61K39/00
CPC分类号: C07K14/47 , A61K2039/505 , C07K14/435 , C07K16/18 , C07K16/3038 , C07K2317/622 , C07K2317/73 , C07K2317/732 , C07K2317/734 , C07K2317/92 , C12N15/113 , C12N2310/14 , C12Q1/6876 , C12Q1/6886 , C12Q2600/118 , C12Q2600/136 , C12Q2600/158 , G01N33/53 , G01N33/57438 , G01N33/57484 , G01N2333/47 , G01N2500/00 , G01N2500/10 , Y10T436/143333
摘要: The present invention provides a method for diagnosing and detecting diseases associated with kidney. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in kidney diseases (KCAT) and antibodies binds to KCATs. The present invention provides that KCATs are used as targets for screening agents that modulates the KCAT activities. Further the present invention provides methods for treating diseases associated with kidney.
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