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    Enzyme producing tartaric acid ether compound and process for producing tartaric acid ether compounds using this enzyme
    1.
    发明授权
    Enzyme producing tartaric acid ether compound and process for producing tartaric acid ether compounds using this enzyme 有权
    产生酒石酸醚的化合物和使用该酶生产酒石酸醚化合物的方法

    公开(公告)号：US06329189B1

    公开(公告)日：2001-12-11

    申请号：US09293986

    申请日：1999-04-19

    申请人： Emiko Kinoshita ,  Tetsuo Aishima ,  Yoshinori Ozawa

    发明人： Emiko Kinoshita ,  Tetsuo Aishima ,  Yoshinori Ozawa

    IPC分类号： C12N988

    CPC分类号： C12N9/88 ,  C12P7/46 ,  C12P17/04 ,  C12P17/06

    摘要： Disclosed in this invention are a novel enzyme producing tartaric acid ether compound which catalyzes a reaction of producing a tartaric acid ether compound in which the phenolic hydroxyl group(s) of a flavonoid or its analogous compound having at least one phenolic hydroxyl group is (are) acted to the epoxy ring of an epoxysuccinic acid to form ether linkage of one or more tartaric acid residues, a process for producing a tartaric acid ether compound by acting the enzyme in the presence of an epoxy-succinic acid and a flavonoid or its analogous compound having at least one phenolic hydroxyl group, and novel tartaric acid ether compounds in which the epoxy ring of an epoxysuccinic acid is bound to the phenolic hydroxyl group(s) of a flavonoid or its analogous compound to form ether linkage of one or more tartaric acid residues. These compounds are useful as a component material of pharmaceuticals and functional foods.

    摘要翻译： 本发明公开了一种生产酒石酸醚化合物的新型酶，其催化产生酒石酸醚化合物的反应，其中具有至少一个酚羟基的类黄酮或其类似化合物的酚羟基为 ）作用于环氧琥珀酸的环氧环以形成一个或多个酒石酸残基的醚键，通过在环氧 - 琥珀酸和类黄酮或其类似物存在下起作用来生产酒石酸醚化合物的方法 具有至少一个酚羟基的化合物和新型酒石酸醚化合物，其中环氧琥珀酸的环氧环与类黄酮或其类似化合物的酚羟基结合形成一个或多个酒石酸的醚键 酸残留。 这些化合物可用作药物和功能性食品的组分材料。

    Method for staining substances having a phosphate group
    2.
    发明申请
    Method for staining substances having a phosphate group 审中-公开
    用于染色具有磷酸基团的物质的方法

    公开(公告)号：US20100099120A1

    公开(公告)日：2010-04-22

    申请号：US11989817

    申请日：2006-08-09

    申请人： Tohru Koike ,  Veiji Kinoshita ,  Emiko Kinoshita

    发明人： Tohru Koike ,  Veiji Kinoshita ,  Emiko Kinoshita

    IPC分类号： G01N33/53 ,  C07F3/06 ,  G01N1/30 ,  G01N33/68 ,  C12Q1/00

    CPC分类号： C07D495/04 ,  C09B57/10 ,  G01N33/58 ,  G01N33/6842 ,  Y10T436/25

    摘要： It is intended to provide a method by which a substance having a phosphate group can be easily detected from a biological sample or the like, a method by which a phosphorylated amino acid residue is easily identified and a compound which can be used in the methods because of having a high coordinate bond forming capacity with a substance having a phosphate group. A metal complex compound represented by the general formula (I): {wherein M represents a metal atom which can be a divalent cation, Rs may be the same or different from one another and represent a hydrogen atom, an alkyl group having 1 to 16 carbon atoms, an acyl group, an alkoxycarbonyl group, an acylalkyl group, an alkoxycarbonylalkyl group, a carboxyalkyl group, a carbamoylalkyl group, a cyanoalkyl group, a hydroxyalkyl group, an aminoalkyl group or a haloalkyl group (here, the carbon number of alkyl moiety of these groups is 1 to 16), a carboxyl group, a carbamoyl group, a cyano group, a hydroxyl group, an amino group or a halogen group, X represents a ligand and Y represents a labeling group} can easily identify a substance having a phosphate group because of having a high coordinate bond forming capacity with a substance having a phosphate group and having the labeling group.

    摘要翻译： 旨在提供一种可以从生物样品等容易地检测具有磷酸基的物质的方法，容易鉴定磷酸化氨基酸残基的方法以及可用于该方法的化合物，因为 与具有磷酸基的物质具有高配位键形成能力。 由通式（I）表示的金属络合物：其中M表示可以是二价阳离子的金属原子，R 3可以相同或不同，表示氢原子，具有1〜16的烷基 碳原子，酰基，烷氧基羰基，酰基烷基，烷氧基羰基烷基，羧基烷基，氨基甲酰基烷基，氰基烷基，羟烷基，氨基烷基或卤代烷基（这里，烷基 这些基团的部分为1至16），羧基，氨基甲酰基，氰基，羟基，氨基或卤素基团，X表示配体，Y表示标记基团}可以容易地鉴定物质 由于与具有磷酸基的物质具有高配位键形成能力并具有标记基团，所以具有磷酸基。