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    Zinc complexes capable of capturing substances having anionic substituents
    1.
    发明申请
    Zinc complexes capable of capturing substances having anionic substituents 有权
    能够捕获具有阴离子取代基的物质的锌络合物

    公开(公告)号：US20050038258A1

    公开(公告)日：2005-02-17

    申请号：US10878131

    申请日：2004-06-21

    申请人： Tohru Koike ,  Masatatsu Suzuki ,  Mitsuhiko Shionoya

    发明人： Tohru Koike ,  Masatatsu Suzuki ,  Mitsuhiko Shionoya

    IPC分类号： C07F3/00 ,  C07F9/12 ,  C07F9/6596 ,  C07D211/68

    CPC分类号： C07F9/6596 ,  C07F3/003 ,  C07F9/12

    摘要： A zinc complex represented by formula (I-0): {wherein R may be the same or different from each other and represents H; an alkyl group having 1 to 16 carbon atoms; an acyl group, a carboxyalkyl group, an acylalkyl group, a carbamoylalkyl group, a cyanoalkyl group, a hydroxyalkyl group, an aminoalkyl group or a haloalkyl group (here, a carbon number at an alkyl portion of these groups is 1 to 16); a carboxyl group; a carbamoyl group; a hydroxyl group; a cyano group; an amino group or; a halogeno group (provided that all are Hs are excluded)} which is capable of capturing a substance having an anionic substituent.

    摘要翻译： 由式（I-0）表示的锌络合物：其中R可以相同或不同，表示H; 具有1至16个碳原子的烷基; 酰基，羧基烷基，酰基烷基，氨基甲酰基烷基，氰基烷基，羟烷基，氨基烷基或卤代烷基（这里，这些基团的烷基部分的碳数为1〜16）。 羧基; 氨基甲酰基; 羟基; 氰基; 氨基或 能够捕获具有阴离子取代基的物质的卤代基团（除了全部为H以外）}。

    SUBSTRATE TREATING SOLUTION AND METHOD EMPLOYING THE SAME FOR TREATING A RESIST SUBSTRATE
    3.
    发明申请
    SUBSTRATE TREATING SOLUTION AND METHOD EMPLOYING THE SAME FOR TREATING A RESIST SUBSTRATE 审中-公开
    基板处理方法及其使用方法，用于处理耐蚀基板

    公开(公告)号：US20110165523A1

    公开(公告)日：2011-07-07

    申请号：US13063666

    申请日：2009-09-14

    申请人： Xiaowei Wang ,  Wenbing Kang ,  Tomohide Katayama ,  Yuriko Matsuura ,  Tohru Koike

    发明人： Xiaowei Wang ,  Wenbing Kang ,  Tomohide Katayama ,  Yuriko Matsuura ,  Tohru Koike

    IPC分类号： G03F7/32

    CPC分类号： G03F7/422

    摘要： The present invention provides a resist substrate treating solution and a method employing the solution for treating a resist substrate. This treating solution enables to remove efficiently resist residues remaining on a surface of the resist substrate after development, and further to miniaturize a resist pattern. The solution is used for treating a resist substrate having a developed photoresist pattern, and comprises a solvent incapable of dissolving the photoresist pattern and a polymer soluble in the solvent. The developed resist substrate is brought into contact with the treating solution, and then washed with a rinse solution such as water to remove efficiently resist residues remaining on the resist substrate surface. The solvent and the polymer are preferably water and a water-soluble polymer, respectively.

    摘要翻译： 本发明提供一种抗蚀剂基板处理液和使用该抗蚀剂基板处理用溶液的方法。 该处理液能够有效地除去显影后残留在抗蚀剂基板的表面上的残留物，进一步使抗蚀剂图案小型化。 该溶液用于处理具有显影的光致抗蚀剂图案的抗蚀剂基板，并且包括不能溶解光致抗蚀剂图案的溶剂和可溶于溶剂的聚合物。 使显影的抗蚀剂基板与处理溶液接触，然后用诸如水的冲洗溶液洗涤以有效地除去残留在抗蚀剂基板表面上的残留物。 溶剂和聚合物分别优选为水和水溶性聚合物。

    Methods for preparing and using a zinc complex
    6.
    发明申请
    Methods for preparing and using a zinc complex 有权
    制备和使用锌络合物的方法

    公开(公告)号：US20080108815A1

    公开(公告)日：2008-05-08

    申请号：US11906256

    申请日：2007-10-01

    申请人： Tohru Koike ,  Masatatsu Suzuki ,  Mitsuhiko Shionoya

    发明人： Tohru Koike ,  Masatatsu Suzuki ,  Mitsuhiko Shionoya

    IPC分类号： C07F3/06

    CPC分类号： C07F9/6596 ,  C07F3/003 ,  C07F9/12

    摘要： A method for capturing a substance having an anionic substituent by contacting a substance having an anionic substituent with a zinc complex such that the substance binds to the zinc complex, the zinc complex being represented by a formula (I): wherein each R is the same or different from each other and each R represents H; an alkyl group having 1 to 16 carbon atoms; an acyl group, a carboxyalkyl group, an acylalkyl group, a carbamoylalkyl group, a cyanoalkyl group, a hydroxyalkyl group, an aminoalkyl group or a haloalkyl group, wherein an alkyl portion of the acyl group, the carboxyalkyl group, the acylalkyl group, the carbamoylalkyl group, the cyanoalkyl group, the hydroxyalkyl group, the aminoalkyl group and the haloalkyl group has 1 to 16 carbon atoms; a carboxyl group; a carbamoyl group; a hydroxyl group; a cyano group; an amino group; or a halogeno group.

    摘要翻译： 通过使具有阴离子取代基的物质与锌络合物接触使得该物质与锌络合物结合的方法，所述锌络合物由式（I）表示：其中每个R相同 或彼此不同，每个R代表H; 具有1至16个碳原子的烷基; 酰基，羧基烷基，酰基烷基，氨基甲酰基烷基，氰基烷基，羟基烷基，氨基烷基或卤代烷基，其中酰基，羧基烷基，酰基烷基， 氨基甲酰基烷基，氰基烷基，羟基烷基，氨基烷基和卤代烷基具有1至16个碳原子; 羧基; 氨基甲酰基; 羟基; 氰基; 氨基; 或卤代基团。

    Method of measuring the molecular weight of phoshoric acid monoester compound and additive for mass spectrum measurement
    8.
    发明申请
    Method of measuring the molecular weight of phoshoric acid monoester compound and additive for mass spectrum measurement 有权
    测定磷酸单酯化合物的分子量和质谱测定添加剂的方法

    公开(公告)号：US20060183237A1

    公开(公告)日：2006-08-17

    申请号：US10547972

    申请日：2003-12-24

    申请人： Tohru Koike ,  Norio Minami ,  Akihiko Kawasaki

    发明人： Tohru Koike ,  Norio Minami ,  Akihiko Kawasaki

    IPC分类号： G01N33/00

    CPC分类号： G01N33/6818 ,  G01N2458/15 ,  Y10S436/815 ,  Y10T436/16

    摘要： The present invention provides a method for confirming existence of a phosphoric acid monoester compound (peptide, saccharine and the like) and easily identifying the molecular weight thereof even among biological samples including a plurality of compounds, and an additive for a mass spectrometry used for the method. In the method according to the present invention, a complex compound exhibiting extremely high coordination ability to a phosphoric acid monoester group and configured of single kind of zinc isotopes is used to obtain a plurality of mass spectrum data, and then the data are compared.

    摘要翻译： 本发明提供了一种用于确认磷酸单酯化合物（肽，糖精等）的存在并且即使在包括多种化合物的生物样品中也容易鉴别其分子量的方法和用于 方法。 在根据本发明的方法中，使用对磷酸单酯基具有极高配位能力并由单种锌同位素构成的配位化合物来获得多个质谱数据，然后比较数据。

    Method for measuring a surface plasmon resonance and noble metal compound used for the same
    9.
    发明授权
    Method for measuring a surface plasmon resonance and noble metal compound used for the same 有权
    用于测量表面等离子体共振的方法和用于其的贵金属化合物

    公开(公告)号：US07804592B2

    公开(公告)日：2010-09-28

    申请号：US10575714

    申请日：2004-10-12

    申请人： Tohru Koike ,  Akihiko Kawasaki ,  Tatsuhiro Kobashi ,  Makoto Takahagi

    发明人： Tohru Koike ,  Akihiko Kawasaki ,  Tatsuhiro Kobashi ,  Makoto Takahagi

    IPC分类号： G01J3/44

    CPC分类号： G01N21/553 ,  C07D213/38 ,  G01J3/44 ,  G01N21/554 ,  G01N21/658 ,  G01N33/54373

    摘要： The present invention provides a method for measuring a surface plasmon resonance, the method enabling easy detection of the existence of a phosphorylated peptide (protein) and determination whether a peptide is phosphorylated or not in biological materials. The present invention also provides a noble metal compound having high capability of coordination to a phosphorylated peptide, and being conveniently usable in the method. A first method for measuring surface plasmon resonance of the present invention comprises: placing a noble metal compound on a bottom face of a prism, irradiating a light to the prism to detect a reflected light, wherein, the noble metal compound has substituents of following formula (I) on a side opposite to a side contacting the prism, and a subject sample is added to a side having the substituent groups (I) in the noble metal compound. [wherein, X represents a linker group]

    摘要翻译： 本发明提供了一种测定表面等离子体共振的方法，该方法能够容易地检测磷酸化肽（蛋白质）的存在并确定生物材料中肽是否被磷酸化。 本发明还提供了与磷酸化肽具有高配位能力的贵金属化合物，并且在该方法中可以方便地使用。 用于测量本发明的表面等离子体共振的第一种方法包括：将贵金属化合物放置在棱镜的底面上，向棱镜照射光以检测反射光，其中贵金属化合物具有下式的取代基 （I）在与棱镜接触的一侧相反的一侧，并且在贵金属化合物中的具有取代基（I）的一侧加入被检样品。 [其中，X表示连接基团]

    Zinc complexes capable of capturing substances having anionic substituents
    10.
    发明授权
    Zinc complexes capable of capturing substances having anionic substituents 有权
    能够捕获具有阴离子取代基的物质的锌络合物

    公开(公告)号：US07358363B2

    公开(公告)日：2008-04-15

    申请号：US10878131

    申请日：2004-06-21

    申请人： Tohru Koike ,  Masatatsu Suzuki ,  Mitsuhiko Shionoya

    发明人： Tohru Koike ,  Masatatsu Suzuki ,  Mitsuhiko Shionoya

    IPC分类号： C07D471/22

    CPC分类号： C07F9/6596 ,  C07F3/003 ,  C07F9/12

    摘要： A zinc complex represented by formula (I-0): {wherein R may be the same or different from each other and represents H; an alkyl group having 1 to 16 carbon atoms; an acyl group, a carboxyalkyl group, an acylalkyl group, a carbamoylalkyl group, a cyanoalkyl group, a hydroxyalkyl group, an aminoalkyl group or a haloalkyl group (here, a carbon number at an alkyl portion of these groups is 1 to 16); a carboxyl group; a carbamoyl group; a hydroxyl group; a cyano group; an amino group or; a halogeno group (provided that all are Hs are excluded)} which is capable of capturing a substance having an anionic substituent.

    摘要翻译： 由式（I-0）表示的锌络合物：其中R可以相同或不同，表示H; 具有1至16个碳原子的烷基; 酰基，羧基烷基，酰基烷基，氨基甲酰基烷基，氰基烷基，羟烷基，氨基烷基或卤代烷基（这里，这些基团的烷基部分的碳数为1〜16）。 羧基; 氨基甲酰基; 羟基; 氰基; 氨基或 能够捕获具有阴离子取代基的物质的卤代基团（除了全部为H以外）}。