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公开(公告)号：US20070054329A1
公开(公告)日：2007-03-08
申请号：US11373833
申请日：2006-03-10
申请人： Eric Fung , Robert Bast , Daniel Chan , Jin Song , Valdimir Podust , Zhen Zhang
发明人： Eric Fung , Robert Bast , Daniel Chan , Jin Song , Valdimir Podust , Zhen Zhang
IPC分类号： G01N33/574
CPC分类号： G01N33/6851 , G01N33/57442 , G01N33/57449 , G01N33/68 , G01N33/74 , G01N2500/00
摘要： The present invention provides protein-based biomarkers and biomarker combinations that are useful in qualifying ovarian cancer status as well as endometrical cancer status in a patient. In particular, it has been found that hepcidin is a biomarker for both ovarian cancer and endometrial cancer and that a panel of biomarkers, including hepcidin, transthyretin and optionally other markers are useful to classify a subject sample as ovarian cancer or non-ovarian cancer. The biomarkers can be detected by SELDI mass spectrometry.
摘要翻译： 本发明提供了可用于鉴定卵巢癌状态以及患者中子宫内膜癌状态的基于蛋白质的生物标志物和生物标志物组合。 特别地，已经发现，铁调素是卵巢癌和子宫内膜癌的生物标志物，并且一组生物标志物，包括铁调素，转甲状腺素蛋白和任选的其他标记物可用于将受试者样品分类为卵巢癌或非卵巢癌。 生物标志物可以通过SELDI质谱检测。
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公开(公告)号：US20100068724A1
公开(公告)日：2010-03-18
申请号：US12381218
申请日：2009-03-09
申请人： Eric T. Fung , Robert Bast , Daniel W. Chan , Jin Song , Valdimir Podust , Zhen Zhang
发明人： Eric T. Fung , Robert Bast , Daniel W. Chan , Jin Song , Valdimir Podust , Zhen Zhang
IPC分类号： G01N33/53 , G01N33/543
CPC分类号： G01N33/6851 , G01N33/57442 , G01N33/57449 , G01N33/68 , G01N33/74 , G01N2500/00
摘要： The present invention provides protein-based biomarkers and biomarker combinations that are useful in qualifying ovarian cancer status as well as endometrical cancer status in a patient. In particular, it has been found that hepcidin is a biomarker for both ovarian cancer and endometrial cancer and that a panel of biomarkers, including hepcidin, transthyretin and optionally other markers are useful to classify a subject sample as ovarian cancer or non-ovarian cancer. The biomarkers can be detected by SELDI mass spectrometry.
摘要翻译： 本发明提供了可用于鉴定卵巢癌状态以及患者中子宫内膜癌状态的基于蛋白质的生物标志物和生物标志物组合。 特别地，已经发现，铁调素是卵巢癌和子宫内膜癌的生物标志物，并且一组生物标志物，包括铁调素，转甲状腺素蛋白和任选的其他标记物可用于将受试者样品分类为卵巢癌或非卵巢癌。 生物标志物可以通过SELDI质谱检测。
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公开(公告)号：US07510842B2
公开(公告)日：2009-03-31
申请号：US11373833
申请日：2006-03-10
申请人： Valdimir Podust , Zhen Zhang , Eric T. Fung , Robert Bast , Daniel W. Chan , Jin Song
发明人： Valdimir Podust , Zhen Zhang , Eric T. Fung , Robert Bast , Daniel W. Chan , Jin Song
IPC分类号： G01N33/53
CPC分类号： G01N33/6851 , G01N33/57442 , G01N33/57449 , G01N33/68 , G01N33/74 , G01N2500/00
摘要： The present invention provides protein-based biomarkers and biomarker combinations that are useful in qualifying ovarian cancer status as well as endometrical cancer status in a patient. In particular, it has been found that hepcidin is a biomarker for both ovarian cancer and endometrial cancer and that a panel of biomarkers, including hepcidin, transthyretin and optionally other markers are useful to classify a subject sample as ovarian cancer or non-ovarian cancer. The biomarkers can be detected by SELDI mass spectrometry.
摘要翻译： 本发明提供了可用于鉴定卵巢癌状态以及患者中子宫内膜癌状态的基于蛋白质的生物标志物和生物标志物组合。 特别地，已经发现，铁调素是卵巢癌和子宫内膜癌的生物标志物，并且一组生物标志物，包括铁调素，转甲状腺素蛋白和任选的其他标记物可用于将受试者样品分类为卵巢癌或非卵巢癌。 生物标志物可以通过SELDI质谱检测。
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公开(公告)号：US20100197561A1
公开(公告)日：2010-08-05
申请号：US11922621
申请日：2006-06-23
CPC分类号： G01N33/6851 , G01N33/57449 , G01N2333/70539 , G01N2500/04
摘要： The present invention provides protein-based biomarkers and biomarker combinations that are useful in qualifying ovarian cancer status in a patient. In particular, the biomarkers of this invention are useful to classify a subject sample as ovarian cancer or non-ovarian cancer. The biomarkers can be detected by SELDI mass spectrometry.
摘要翻译： 本发明提供了可用于评估患者卵巢癌状态的基于蛋白质的生物标志物和生物标志物组合。 特别地，本发明的生物标志物可用于将受试者样品分类为卵巢癌或非卵巢癌。 生物标志物可以通过SELDI质谱检测。
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5.发明申请METHODS OF DETECTING A FRAGMENT OF NEUROSECRETORY PROTEIN VGF FOR DIAGNOSING ALZHEIMER'S DISEASE 审中-公开检测神经病毒蛋白VGF片段用于诊断阿尔茨海默病的方法公开(公告)号：US20110294865A1
公开(公告)日：2011-12-01
申请号：US12829630
申请日：2010-07-02
IPC分类号： A61K31/7088 , C07K17/00 , C07K16/18 , G06F19/10 , G01N33/566 , G01N33/53 , C12N5/02 , A61P25/28 , C07K14/435 , C07K19/00
CPC分类号： G01N33/6896 , G01N33/6842 , G01N33/6848 , G01N33/6851 , G01N2800/2821
摘要： The present invention provides a neurosecretory protein VGF peptide useful in qualifying Alzheimer's disease status in a patient. In particular, this peptide and modified forms thereof may be used to classify a subject sample as Alzheimer's disease or non-Alzheimer's disease. The peptide biomarker can be detected by SELDI mass spectrometry.
摘要翻译： 本发明提供了可用于评估患者中阿尔茨海默病状态的神经分泌蛋白VGF肽。 特别地，该肽及其修饰形式可用于将受试者样品分类为阿尔茨海默病或非阿尔茨海默氏病。 肽生物标志物可以通过SELDI质谱法检测。
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