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1.发明申请TURKEY HERPESVIRUS VECTORED RECOMBINANT CONTAINING AVIAN INFLUENZA GENES 有权土耳其草药含有AVIAN INFLUENZA GENESVIRUS的重组体公开(公告)号：US20100092510A1
公开(公告)日：2010-04-15
申请号：US12449037
申请日：2008-03-28
IPC分类号： A61K39/245 , C12N7/01 , A61K39/145
CPC分类号： C12N15/86 , A61K39/12 , A61K39/145 , A61K2039/5256 , C07K14/005 , C07K14/11 , C12N7/00 , C12N15/63 , C12N15/85 , C12N15/869 , C12N2710/16143 , C12N2710/16334 , C12N2710/16343 , C12N2710/16443 , C12N2760/16134 , C12N2830/34 , C12N2830/60
摘要： The present invention provides a recombinant turkey herpesvirus modified by the presence of the cDNA encoding the hemagglutinin protein of avian influenza virus under a promoter. A poultry vaccine comprising the recombinant turkey herpesvirus described in the present invention can induce serological responses that may be easily detected by the hemagglutination inhibition assay but not by commercially available diagnostic ELISA kits; thus enabling easy differentiation between vaccination and field infection.
摘要翻译： 本发明提供了通过在启动子下编码禽流感病毒血凝素蛋白的cDNA的存在而修饰的重组火鸡疱疹病毒。 包含本发明描述的重组火鸡疱疹病毒的家禽疫苗可以诱导血清学反应，其可以通过血细胞凝集抑制测定容易地检测，但不能通过市售的诊断ELISA试剂盒检测; 从而使疫苗接种和野外感染之间容易分化。
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2.发明授权公开(公告)号：US08927270B2
公开(公告)日：2015-01-06
申请号：US12449037
申请日：2008-03-28
IPC分类号： C12N15/63 , A61K39/145 , C07K14/11 , C12N15/869 , C12N15/85 , C12N15/86 , C12N7/00 , A61K39/00
CPC分类号： C12N15/86 , A61K39/12 , A61K39/145 , A61K2039/5256 , C07K14/005 , C07K14/11 , C12N7/00 , C12N15/63 , C12N15/85 , C12N15/869 , C12N2710/16143 , C12N2710/16334 , C12N2710/16343 , C12N2710/16443 , C12N2760/16134 , C12N2830/34 , C12N2830/60
摘要： The present invention provides a recombinant turkey herpesvirus modified by the presence of the cDNA encoding the hemagglutinin protein of avian influenza virus under a promoter. A poultry vaccine comprising the recombinant turkey herpesvirus described in the present invention can induce serological responses that may be easily detected by the hemagglutination inhibition assay but not by commercially available diagnostic ELISA kits; thus enabling easy differentiation between vaccination and field infection.
摘要翻译： 本发明提供了通过在启动子下编码禽流感病毒血凝素蛋白的cDNA的存在而修饰的重组火鸡疱疹病毒。 包含本发明描述的重组火鸡疱疹病毒的家禽疫苗可以诱导血清学反应，其可以通过血细胞凝集抑制测定容易地检测，但不能通过市售的诊断ELISA试剂盒检测; 从而使疫苗接种和野外感染之间容易分化。
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3.发明申请公开(公告)号：US20080241188A1
公开(公告)日：2008-10-02
申请号：US11729978
申请日：2007-03-30
CPC分类号： C12N15/86 , A61K39/12 , A61K39/145 , A61K2039/5256 , C07K14/005 , C07K14/11 , C12N7/00 , C12N15/63 , C12N15/85 , C12N15/869 , C12N2710/16143 , C12N2710/16334 , C12N2710/16343 , C12N2710/16443 , C12N2760/16134 , C12N2830/34 , C12N2830/60
摘要： The present invention provides a recombinant turkey herpesvirus modified by the presence of the cDNA encoding the hemagglutinin protein of avian influenza virus under a promoter. A poultry vaccine comprising the recombinant turkey herpesvirus described in the present invention can induce serological responses that may be easily detected by the hemagglutination inhibition assay but not by commercially available diagnostic ELISA kits; thus enabling easy differentiation between vaccination and field infection.
摘要翻译： 本发明提供了通过在启动子下编码禽流感病毒血凝素蛋白的cDNA的存在而修饰的重组火鸡疱疹病毒。 包含本发明描述的重组火鸡疱疹病毒的家禽疫苗可以诱导血清学反应，其可以通过血细胞凝集抑制测定容易地检测，但不能通过市售的诊断ELISA试剂盒检测; 从而使疫苗接种和野外感染之间容易分化。
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