公开(公告)号：US10376674B2

公开(公告)日：2019-08-13

申请号：US14485853

申请日：2014-09-15

申请人： Ethicon, Inc.

发明人： Kevin Weadock ,  Jeffrey Hammond

IPC分类号： A61B17/34 ,  A61M25/01 ,  A61N5/10 ,  A61K31/7068 ,  A61K31/513 ,  A61K31/4375 ,  A61K31/282 ,  A61K38/38 ,  A61K33/24 ,  A61K31/704 ,  A61K31/337 ,  A61N5/02 ,  A61N1/20 ,  A61N5/00 ,  A61M25/09 ,  A61B1/04 ,  A61B1/06 ,  A61N1/05 ,  A61M25/06 ,  A61M31/00 ,  A61M37/00 ,  A61B90/00 ,  A61N1/32 ,  A61B1/015 ,  A61B5/00 ,  A61B18/00 ,  A61B10/02 ,  A61B6/12 ,  A61B8/08 ,  A61B5/055

摘要： Novel systems for and methods of delivering therapeutic agents to target tissues are disclosed. The method of delivering a therapeutic agent to a target tissue involves identifying a target tissue via an imaging modality and then using a guidewire capable of anchoring in tissue to advance a cannula to the target tissue. The guidewire and novel cannula configurations enable rapid and repeated treatments of the target tissue without the need for subsequent imaging. The cannula is coupled to a source of ultrasound, radiation, radiofrequency energy, or chemotherapeutic agents which can then be delivered to from the cannula the target tissue. The system and method can be used to treat tumors that are small or surgically inoperable. In addition, the system can be used to treat lymphatic tissue that may contain metastases from the tumors.

公开(公告)号：US20180110964A1

公开(公告)日：2018-04-26

申请号：US15848114

申请日：2017-12-20

申请人： Ethicon, Inc.

发明人： Kevin Weadock ,  Jeffrey Hammond

IPC分类号： A61M25/01 ,  A61N5/10 ,  A61B1/04 ,  A61B1/06 ,  A61B17/34 ,  A61K31/282 ,  A61K31/337 ,  A61K31/4375 ,  A61K31/513 ,  A61K31/704 ,  A61K31/7068 ,  A61K33/24 ,  A61K38/38 ,  A61M25/06 ,  A61M25/09 ,  A61M31/00 ,  A61M37/00 ,  A61N1/05 ,  A61N1/20 ,  A61N5/02 ,  A61N5/00 ,  A61B6/12 ,  A61B10/02 ,  A61B1/015 ,  A61B18/00 ,  A61N1/32 ,  A61B5/055 ,  A61B5/00 ,  A61B8/08

CPC分类号： A61M25/0169 ,  A61B1/015 ,  A61B1/04 ,  A61B1/06 ,  A61B5/055 ,  A61B5/4839 ,  A61B6/12 ,  A61B8/085 ,  A61B10/0233 ,  A61B17/3415 ,  A61B17/3421 ,  A61B17/3468 ,  A61B90/361 ,  A61B90/39 ,  A61B2017/3445 ,  A61B2018/00005 ,  A61B2018/00273 ,  A61B2018/00601 ,  A61B2018/00613 ,  A61B2018/00982 ,  A61B2018/00994 ,  A61B2090/3908 ,  A61B2090/3987 ,  A61K31/282 ,  A61K31/337 ,  A61K31/4375 ,  A61K31/513 ,  A61K31/704 ,  A61K31/7068 ,  A61K33/24 ,  A61K38/385 ,  A61M25/06 ,  A61M25/09 ,  A61M31/00 ,  A61M31/002 ,  A61M31/007 ,  A61M37/0092 ,  A61M2025/0166 ,  A61M2025/09125 ,  A61M2025/09141 ,  A61M2025/09166 ,  A61M2025/09175 ,  A61N1/05 ,  A61N1/20 ,  A61N1/327 ,  A61N5/00 ,  A61N5/02 ,  A61N5/1001 ,  A61N5/1027

摘要： Novel systems for and methods of delivering therapeutic agents to target tissues are disclosed. The method of delivering a therapeutic agent to a target tissue involves identifying a target tissue via an imaging modality and then using a guidewire capable of anchoring in tissue to advance a cannula to the target tissue. The guidewire and novel cannula configurations enable rapid and repeated treatments of the target tissue without the need for subsequent imaging. The cannula is coupled to a source of ultrasound, radiation, radiofrequency energy, or chemotherapeutic agents which can then be delivered to from the cannula the target tissue. The system and method can be used to treat tumors that are small or surgically inoperable. In addition, the system can be used to treat lymphatic tissue that may contain metastases from the tumors.

公开(公告)号：US20160074626A1

公开(公告)日：2016-03-17

申请号：US14485853

申请日：2014-09-15

申请人： Ethicon, Inc.

发明人： Kevin Weadock ,  Jeffrey Hammond

IPC分类号： A61M25/01 ,  A61K31/513 ,  A61K31/4375 ,  A61K31/282 ,  A61K38/38 ,  A61K33/24 ,  A61K31/704 ,  A61K31/337 ,  A61N5/02 ,  A61N1/20 ,  A61N1/32 ,  A61F7/12 ,  A61M5/142 ,  A61N5/00 ,  A61M25/09 ,  A61B17/34 ,  A61N5/10 ,  A61N7/02 ,  A61B1/04 ,  A61B1/06 ,  A61B1/015 ,  A61K31/7068

CPC分类号： A61M25/0169 ,  A61B1/015 ,  A61B1/04 ,  A61B1/06 ,  A61B5/055 ,  A61B5/4839 ,  A61B6/12 ,  A61B8/085 ,  A61B10/0233 ,  A61B17/3415 ,  A61B17/3421 ,  A61B17/3468 ,  A61B90/361 ,  A61B90/39 ,  A61B2017/3445 ,  A61B2018/00005 ,  A61B2018/00273 ,  A61B2018/00601 ,  A61B2018/00613 ,  A61B2018/00982 ,  A61B2018/00994 ,  A61B2090/3908 ,  A61B2090/3987 ,  A61K31/282 ,  A61K31/337 ,  A61K31/4375 ,  A61K31/513 ,  A61K31/704 ,  A61K31/7068 ,  A61K33/24 ,  A61K38/385 ,  A61M25/06 ,  A61M25/09 ,  A61M31/00 ,  A61M31/002 ,  A61M31/007 ,  A61M37/0092 ,  A61M2025/0166 ,  A61M2025/09125 ,  A61M2025/09141 ,  A61M2025/09166 ,  A61M2025/09175 ,  A61N1/05 ,  A61N1/20 ,  A61N1/327 ,  A61N5/00 ,  A61N5/02 ,  A61N5/1001 ,  A61N5/1027

摘要： Novel systems for and methods of delivering therapeutic agents to target tissues are disclosed. The method of delivering a therapeutic agent to a target tissue involves identifying a target tissue via an imaging modality and then using a guidewire capable of anchoring in tissue to advance a cannula to the target tissue. The guidewire and novel cannula configurations enable rapid and repeated treatments of the target tissue without the need for subsequent imaging. The cannula is coupled to a source of ultrasound, radiation, radiofrequency energy, or chemotherapeutic agents which can then be delivered to from the cannula the target tissue. The system and method can be used to treat tumors that are small or surgically inoperable. In addition, the system can be used to treat lymphatic tissue that may contain metastases from the tumors.

摘要翻译： 公开了将治疗剂递送至靶组织的新系统和方法。 将治疗剂递送到靶组织的方法包括经由成像模态识别靶组织，然后使用能够锚定在组织中的导线将套管推进到靶组织。 导丝和新颖的插管配置使得能够快速且重复地对靶组织进行处理，而不需要随后的成像。 套管耦合到超声，辐射，射频能量或化学治疗剂的源，然后可以从套管向目标组织传递。 该系统和方法可用于治疗小或手术不能手术的肿瘤。 此外，该系统可用于治疗可能含有肿瘤转移的淋巴组织。