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12 条记录 (耗时 0.031 秒)

    TREATMENT OF OCULAR INFLAMMATORY DISEASES USING LAQUINIMOD
    4.
    发明申请
    TREATMENT OF OCULAR INFLAMMATORY DISEASES USING LAQUINIMOD 审中-公开

    公开(公告)号：US20170231971A1

    公开(公告)日：2017-08-17

    申请号：US15582162

    申请日：2017-04-28

    申请人： Joel Kaye ,  Hussein Hallak ,  Nora Tarcic

    发明人： Joel Kaye ,  Hussein Hallak ,  Nora Tarcic

    IPC分类号： A61K31/4704 ,  A61K9/00 ,  A61K9/08

    CPC分类号： A61K31/4704 ,  A61K9/0048 ,  A61K9/0053 ,  A61K9/08

    摘要： Disclosed is a method for treating an ocular inflammatory disease (OID), e.g., uveitis or conjunctivitis, comprising periodic administration of a therapeutically effective amount of laquinimod or a pharmaceutically acceptable salt thereof. Also provided is a pharmaceutical composition comprising laquinimod or a pharmaceutically acceptable salt thereof for use in treating a subject suffering from an OID, uveitis, bacterial conjunctivitis, viral conjunctivitis, an inflammation of the orbital tissue, the lacrimal apparatus, the eyelid, the cornea, the retina or the optic pathway. This application also provides a method for treating a subject suffering from an autoimmune disease-associated ocular inflammation comprising periodic ocular administration to the subject a therapeutically effective amount of laquinimod or a pharmaceutically acceptable salt, and an ocular pharmaceutical composition comprising laquinimod or a pharmaceutically acceptable salt thereof for use in treating an autoimmune disease-associated ocular inflammation.

    TREATMENT OF OCULAR INFLAMMATORY DISEASES USING LAQUINIMOD
    5.
    发明申请
    TREATMENT OF OCULAR INFLAMMATORY DISEASES USING LAQUINIMOD 审中-公开

    公开(公告)号：US20180071275A1

    公开(公告)日：2018-03-15

    申请号：US15816402

    申请日：2017-11-17

    申请人： Joel Kaye ,  Hussein Hallak ,  Nora Tarcic

    发明人： Joel Kaye ,  Hussein Hallak ,  Nora Tarcic

    IPC分类号： A61K31/4704 ,  A61K9/00 ,  A61K9/08

    CPC分类号： A61K31/4704 ,  A61K9/0048 ,  A61K9/0053 ,  A61K9/08

    摘要： Disclosed is a method for treating an ocular inflammatory disease (OID), e.g., uveitis or conjunctivitis, comprising periodic administration of a therapeutically effective amount of laquinimod or a pharmaceutically acceptable salt thereof. Also provided is a pharmaceutical composition comprising laquinimod or a pharmaceutically acceptable salt thereof for use in treating a subject suffering from an OID, uveitis, bacterial conjunctivitis, viral conjunctivitis, an inflammation of the orbital tissue, the lacrimal apparatus, the eyelid, the cornea, the retina or the optic pathway. This application also provides a method for treating a subject suffering from an autoimmune disease-associated ocular inflammation comprising periodic ocular administration to the subject a therapeutically effective amount of laquinimod or a pharmaceutically acceptable salt, and an ocular pharmaceutical composition comprising laquinimod or a pharmaceutically acceptable salt thereof for use in treating an autoimmune disease-associated ocular inflammation.

    TREATMENT OF OCULAR INFLAMMATORY DISEASES USING LAQUINIMOD
    8.
    发明申请
    TREATMENT OF OCULAR INFLAMMATORY DISEASES USING LAQUINIMOD 审中-公开

    公开(公告)号：US20170333420A1

    公开(公告)日：2017-11-23

    申请号：US15670684

    申请日：2017-08-07

    申请人： Joel Kaye ,  Hussein Hallak ,  Nora Tarcic

    发明人： Joel Kaye ,  Hussein Hallak ,  Nora Tarcic

    IPC分类号： A61K31/4704 ,  A61K9/00 ,  A61K9/08

    CPC分类号： A61K31/4704 ,  A61K9/0048 ,  A61K9/0053 ,  A61K9/08

    摘要： Disclosed is a method for treating an ocular inflammatory disease (OID), e.g., uveitis or conjunctivitis, comprising periodic administration of a therapeutically effective amount of laquinimod or a pharmaceutically acceptable salt thereof. Also provided is a pharmaceutical composition comprising laquinimod or a pharmaceutically acceptable salt thereof for use in treating a subject suffering from an OID, uveitis, bacterial conjunctivitis, viral conjunctivitis, an inflammation of the orbital tissue, the lacrimal apparatus, the eyelid, the cornea, the retina or the optic pathway. This application also provides a method for treating a subject suffering from an autoimmune disease-associated ocular inflammation comprising periodic ocular administration to the subject a therapeutically effective amount of laquinimod or a pharmaceutically acceptable salt, and an ocular pharmaceutical composition comprising laquinimod or a pharmaceutically acceptable salt thereof for use in treating an autoimmune disease-associated ocular inflammation.

    TREATMENT OF MULTIPLE SCLEROSIS WITH COMBINATION OF LAQUINIMOD AND FINGOLIMOD
    10.
    发明申请
    TREATMENT OF MULTIPLE SCLEROSIS WITH COMBINATION OF LAQUINIMOD AND FINGOLIMOD 审中-公开
    多药联合治疗多发性硬化

    公开(公告)号：US20150037263A1

    公开(公告)日：2015-02-05

    申请号：US14520145

    申请日：2014-10-21

    申请人： Hussein Hallak ,  Nora Tarcic ,  Joel Flaxman Kaye

    发明人： Hussein Hallak ,  Nora Tarcic ,  Joel Flaxman Kaye

    IPC分类号： A61K31/47 ,  A61K45/06 ,  A61J1/03 ,  A61K31/137

    CPC分类号： A61K31/47 ,  A61J1/035 ,  A61K9/0053 ,  A61K9/14 ,  A61K9/28 ,  A61K9/48 ,  A61K31/137 ,  A61K31/4704 ,  A61K45/06 ,  A61K47/02 ,  A61K47/26 ,  A61K2300/00

    摘要： This invention provides a method of treating a subject afflicted with multiple sclerosis or presenting a clinically isolated syndrome comprising administering to the subject laquinimod as an add-on therapy to or in combination with fingolimod. This invention also provides a package and a pharmaceutical composition comprising laquinimod and fingolimod for treating a subject afflicted with multiple sclerosis or presenting a clinically isolated syndrome. This invention also provides laquinimod for use as an add-on therapy or in combination with fingolimod in treating a subject afflicted with multiple sclerosis or presenting a clinically isolated syndrome. This invention further provides use of laquinimod and fingolimod in the preparation of a combination for treating a subject afflicted with multiple sclerosis or presenting a clinically isolated syndrome.

    摘要翻译： 本发明提供了治疗患有多发性硬化或呈现临床分离综合征的受试者的方法，其包括以与芬戈莫德组合的附加疗法给予所述受试者的拉喹莫德。 本发明还提供一种包含药物组合物，其包含拉喹莫德和芬戈莫德，用于治疗患有多发性硬化症或呈现临床分离综合征的受试者。 本发明还提供了用作附加疗法或与芬戈莫德组合用于治疗患有多发性硬化症或呈现临床孤立综合征的受试者的拉喹莫德。 本发明还提供了拉喹莫德和芬戈莫德在制备用于治疗患有多发性硬化症或呈现临床分离综合征的受试者的组合的用途。