公开(公告)号：US20220296654A1

公开(公告)日：2022-09-22

申请号：US17618725

申请日：2020-06-11

Applicant: Evelo Biosciences, Inc

Inventor： Alicia Ballok ,  Mark Bodmer ,  Baundauna Bose ,  Sofia M. Carlton ,  Taylor A. Cormack ,  Christopher J.H. Davitt ,  Loise Francisco-Anderson ,  Brian Goodman ,  Andrea ltano ,  Nihal Okan ,  Holly Ponichtera ,  Erin B. Troy ,  Fabian B. Romano-Chernac ,  Maria Sizova

IPC: A61K35/74 ,  A61K35/744 ,  A61K35/745 ,  A61P35/00 ,  A61P37/00

Abstract: Provided herein are methods and pharmaceutical compositions related to processed microbial extracellular vesicles (pmEVs) that can be useful as therapeutic agents.

公开(公告)号：US20190350987A1

公开(公告)日：2019-11-21

申请号：US16268745

申请日：2019-02-06

Applicant: Evelo Biosciences, Inc.

Inventor： Brian Goodman ,  Baundauna Bose ,  Christopher J.H. Davitt ,  Maria Sizova ,  Sofia M.R. Carlton ,  Andrea Itano ,  Holly Ponichtera ,  Taylor A. Cormack

IPC: A61K35/74 ,  A61K45/06 ,  A61P37/06 ,  A61P19/02 ,  A61P3/10 ,  A61P1/16 ,  A61P17/06 ,  A61P35/00

Abstract: Provided herein are methods and compositions related to Veillonella bacteria useful as therapeutic agents.

公开(公告)号：US11266700B2

公开(公告)日：2022-03-08

申请号：US16192172

申请日：2018-11-15

Applicant: Evelo Biosciences, Inc.

Inventor： Brian Goodman ,  Holly Ponichtera ,  Andrea Itano ,  Mark Bodmer ,  Taylor A. Cormack ,  Maria Sizova ,  Carolina Baez-Giangreco ,  Duncan McHale ,  Kritika Ramani

IPC: A61K35/744 ,  A61K45/00 ,  A61K35/00 ,  A61P29/00 ,  A61P17/06 ,  A61P37/06 ,  C12N1/20 ,  C12R1/225

Abstract: Provided herein are methods and compositions related to immune modulating Lactococcus strains useful as therapeutic agents. In certain embodiments, provided herein are methods of treating an immune disorder in a subject comprising administering to the subject a bacterial composition comprising Lactococcus lactis cremoris Strain A (ATCC Deposit Number PTA-125368).

公开(公告)号：US11090341B2

公开(公告)日：2021-08-17

申请号：US16268745

申请日：2019-02-06

Applicant: Evelo Biosciences, Inc.

Inventor： Brian Goodman ,  Baundauna Bose ,  Christopher J. H. Davitt ,  Maria Sizova ,  Sofia M. R. Carlton ,  Andrea Itano ,  Holly Ponichtera ,  Taylor A. Cormack ,  Kritika Ramani

IPC: A61K35/74 ,  A61P17/06 ,  A61P1/16 ,  A61P37/06 ,  A61P19/02 ,  A61P3/10 ,  A61P35/00 ,  A61K45/06

Abstract: Provided herein are methods and compositions related to Veillonella bacteria useful as therapeutic agents.

公开(公告)号：US20230256032A1

公开(公告)日：2023-08-17

申请号：US18005145

申请日：2021-07-20

Applicant: Evelo Biosciences, Inc.

Inventor： Mark Bodner ,  William Caffry ,  Taylor A. Cormack ,  Valeria Kravitz ,  Alline Pacheco ,  Holly Ponichtera ,  Kritika Ramani ,  Maria Sizova ,  Leslie Wardwell-Scott

IPC: A61K35/74 ,  A61K9/50 ,  A61K9/00 ,  A61P29/00

CPC classification number: A61K35/74 ,  A61K9/5005 ,  A61K9/0053 ,  A61K9/0019 ,  A61P29/00

Abstract: Provided herein are methods and pharmaceutical compositions related to the bacteria and microbial extracellular vesicles (mEVs) of Prevotella histicola Strain C that are useful as therapeutic agents, e.g., for treating inflammatory diseases (e.g., a neuroinflammatory disease).

公开(公告)号：US20220249579A1

公开(公告)日：2022-08-11

申请号：US17618679

申请日：2020-06-11

Applicant: Evelo Biosciences, Inc.

Inventor： Alicia Ballok ,  Mark Bodmer ,  Baundauna Bosse ,  Sofia M. Carlton ,  Taylor A. Cormack ,  Christopher J. Davitt ,  Loise Francisco-Anderson ,  Brian Goodman ,  Andrea Itano ,  Nihal Okan ,  Holly Ponichtera ,  Erin B. Troy ,  Fabian B. Romano-Chernac ,  Maria Sizova

IPC: A61K35/745 ,  A61P37/06 ,  A61K45/06 ,  A61K9/00

Abstract: Provided herein are methods and pharmaceutical compositions related to secreted microbial extracellular vesicles (smEVs) that can be useful as therapeutic agents.

公开(公告)号：US20190216862A1

公开(公告)日：2019-07-18

申请号：US16190735

申请日：2018-11-14

Applicant: Evelo Biosciences, Inc.

Inventor： Brian Goodman ,  Holly Ponichtera ,  Andrea Itano ,  Taylor A. Cormack ,  Maria Sizova ,  Valeria Kravitz ,  Ekaterina Gavrish ,  Carolina Baez-Giangreco

IPC: A61K35/742 ,  A61P37/00 ,  A61P35/00 ,  C12R1/01

CPC classification number: A61K35/742 ,  A61K35/74 ,  A61P35/00 ,  A61P37/00 ,  C12N1/20 ,  C12R1/01

Abstract: Provided herein are methods and compositions related to Blautia Strain A useful as therapeutic agents.

公开(公告)号：US20220339208A1

公开(公告)日：2022-10-27

申请号：US17633105

申请日：2020-08-04

Applicant: Evelo Biosciences, Inc.

Inventor： S. M. Abel ,  Kristie Barth ,  Mark Bodmer ,  Taylor A. Cormack ,  Tanmoy Ganguly ,  Humphrey Gardner ,  Andrea Itano ,  Duncan McHale ,  Mustafa Noor ,  Holly Ponichtera ,  Kritika Ramani ,  Peter Sandy

IPC: A61K35/74 ,  A61K9/00 ,  A61P17/00 ,  A61P17/06

Abstract: Provided herein are methods and compositions related to Prevotella bacteria useful as therapeutic agents, e.g., for the treatment of psoriasis or atopic dermatitis.

公开(公告)号：US10702561B2

公开(公告)日：2020-07-07

申请号：US16595085

申请日：2019-10-07

Applicant: Evelo Biosciences, Inc.

Inventor： Brian Goodman ,  Holly Ponichtera ,  Andrea Itano ,  Taylor A. Cormack ,  Maria Sizova ,  Valeria Kravitz ,  Ekaterina Gavrish ,  Carolina Baez-giangreco

IPC: A01N63/00 ,  A61K35/742 ,  C12R1/01 ,  A61P35/00 ,  A61P37/00 ,  C12N1/20 ,  A61K35/74

Abstract: Provided herein are pharmaceutical compositions related to a Blautia strain useful as a therapeutic agent.

公开(公告)号：US20200030389A1

公开(公告)日：2020-01-30

申请号：US16595085

申请日：2019-10-07

Applicant: Evelo Biosciences, Inc.

Inventor： Brian Goodman ,  Holly Ponichtera ,  Andrea Itano ,  Taylor A. Cormack ,  Maria Sizova ,  Valeria Kravitz ,  Ekaterina Gavrish ,  Carolina Baez-giangreco

IPC: A61K35/742 ,  C12R1/01 ,  A61P35/00 ,  A61P37/00 ,  C12N1/20 ,  A61K35/74

Abstract: Provided herein are pharmaceutical compositions related to a Blautia strain useful as a therapeutic agent.