-
1.发明授权Cyanine derivatives having meso-reactive functional group at polymethine chain and preparation method thereof 有权在聚甲炔链上具有中等反应性官能团的花青衍生物及其制备方法公开(公告)号：US09151735B2
公开(公告)日：2015-10-06
申请号：US13813764
申请日：2013-01-07
发明人： Juyoung Yoon , Guo Zhiqian
IPC分类号： G01N31/22 , G01N31/00 , C07D403/08 , C07D403/02 , C07D209/14 , G01N33/84 , C09B23/01
CPC分类号： G01N31/221 , C07D209/14 , C07D403/08 , C09B23/0041 , C09B23/0066 , G01N33/84 , Y10T436/163333
摘要： The present invention relates to a novel cyanne derivative having a meso-reaction functional group in a polymethine chain, and a preparation method thereof, and the cyanine derivative having the reaction functional group substituted at the meso site may be suitable for mass production thanks to a very simple synthesis method, have a very fast reaction rate because while a related art reagent for detection of nerve agents undergoes two steps of reactions, the cyanine derivative of the present invention undergoes only one step of reaction, have very excellent sensitivity, and be useful as an acid pH-activated ratiometric NIR probe because it is able to be activated in an acidic pH and is usable in an aqueous environment.
摘要翻译： 本发明涉及一种在聚甲炔链中具有内消旋反应官能团的新型氰化物衍生物及其制备方法，并且具有在中间位置被取代的反应官能团的花青衍生物可适用于批量生产 非常简单的合成方法，具有非常快的反应速率，因为当用于检测神经药物的现有技术试剂经历两步反应时，本发明的花青衍生物仅经历一个反应步骤，具有非常优异的灵敏度，并且是有用的 作为酸性pH活化的比率NIR探针，因为它能够在酸性pH下活化并且可用于水性环境中。
-
2.发明申请NOVEL CYANINE DERIVATIVES HAVING MESO-REACTIVE FUNCTIONAL GROUP AT POLYMETHINE CHAIN AND PREPARATION METHOD THEREOF 有权在聚四氟乙烯链上具有MESO反应性官能团的新型氰胺衍生物及其制备方法公开(公告)号：US20140329331A1
公开(公告)日：2014-11-06
申请号：US13813764
申请日：2013-01-07
发明人： Juyoung Yoon , Guo Zhiqian
IPC分类号： G01N31/22 , C07D403/08
CPC分类号： G01N31/221 , C07D209/14 , C07D403/08 , C09B23/0041 , C09B23/0066 , G01N33/84 , Y10T436/163333
摘要： The present invention relates to a novel cyanne derivative having a meso-reaction functional group in a polymethine chain, and a preparation method thereof, and the cyanine derivative having the reaction functional group substituted at the meso site may be suitable for mass production thanks to a very simple synthesis method, have a very fast reaction rate because while a related art reagent for detection of nerve agents undergoes two steps of reactions, the cyanine derivative of the present invention undergoes only one step of reaction, have very excellent sensitivity, and be useful as an acid pH-activated ratiometric NIR probe because it is able to be activated in an acidic pH and is usable in an aqueous environment.
摘要翻译： 本发明涉及一种在聚甲炔链中具有内消旋反应官能团的新型氰化物衍生物及其制备方法，并且具有在中间位置被取代的反应官能团的花青衍生物可适用于批量生产 非常简单的合成方法，具有非常快的反应速率，因为当用于检测神经药物的现有技术试剂经历两步反应时，本发明的花青衍生物仅经历一个反应步骤，具有非常优异的灵敏度，并且是有用的 作为酸性pH活化的比率NIR探针，因为它能够在酸性pH下活化并且可用于水性环境中。
-
搜索结果
2 条记录 (耗时 0.011 秒)
