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公开(公告)号：US20110206643A1
公开(公告)日：2011-08-25
申请号：US11921546
申请日：2006-05-31
申请人： Valentin Fulga , Robert Michael Clark , Yael Porat , Danny Belkin , Avner Schrift , Eyal Teichman
发明人： Valentin Fulga , Robert Michael Clark , Yael Porat , Danny Belkin , Avner Schrift , Eyal Teichman
摘要： A method for automated cell processing is provided, including receiving at least one tissue containing a multiplicity of cells belonging to multiple cell types, and automatically increasing both the proportion of cells of at least one of said multiple cell types as compared with at least another of said multiple cell types and the absolute number of cells of said at least one of said multiple cell types. Other embodiments are also described.
摘要翻译： 提供了一种用于自动细胞处理的方法，包括接收至少一个包含多个细胞类型的细胞的组织，并且与至少另一种细胞相比，自动增加所述多种细胞类型中的至少一种细胞的比例 所述多种细胞类型和所述多种细胞类型中的所述至少一种的细胞的绝对数目。 还描述了其它实施例。
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2.发明授权Method and system for coating a medical device using optical drop volume verification 失效使用光学液滴体积验证涂覆医疗器械的方法和系统公开(公告)号：US07749553B2
公开(公告)日：2010-07-06
申请号：US11047282
申请日：2005-01-31
申请人： Eyal Teichman , Avner Schrift
发明人： Eyal Teichman , Avner Schrift
IPC分类号： B05C11/00 , C23C16/52 , B41J29/373
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/91525 , A61F2002/91533 , A61F2002/91575 , A61F2230/0054 , B05B12/082 , B05B13/0442
摘要： A method and apparatus for controlling coating material deposition on to a medical device. Images of material drops in flight are captured and an average single drop volume value is calculated by conversion of the captured drop images to a volume measurement. The average single drop volume value is used to calculate a total number of drops necessary to apply a desired amount of coating. Alternately, material is applied and the amount of material deposited is accumulated and adjustments are made to deposit only a desired amount of coating material. A drop volume is determined for either every drop or a sampling of drops as the drops are being applied. Adjustments to the coating process include changing drop size and changing a number of drops to be deposited.
摘要翻译： 一种用于控制涂覆材料沉积到医疗装置上的方法和装置。 捕获飞行中物质滴的图像，通过将捕获的液滴图像转换为体积测量来计算平均单滴体积值。 平均单滴体积值用于计算施加所需量涂层所需的总滴数。 或者，施加材料并且堆积的材料的量被累积并且进行调整以仅沉积所需量的涂层材料。 随着液滴的应用，每滴滴或液滴的取样确定液滴体积。 对涂布过程的调整包括改变液滴尺寸和改变要沉积的液滴数量。
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3.发明申请Method and System for Coating a Medical Device Using Optical Drop Volume Verification 有权使用光滴体积验证涂覆医疗器械的方法和系统公开(公告)号：US20100300356A1
公开(公告)日：2010-12-02
申请号：US12826059
申请日：2010-06-29
申请人： Eyal Teichman , Avner Schrift
发明人： Eyal Teichman , Avner Schrift
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/91525 , A61F2002/91533 , A61F2002/91575 , A61F2230/0054 , B05B12/082 , B05B13/0442
摘要： A method and apparatus for controlling coating material deposition on to a medical device. Images of material drops in flight are captured and an average single drop volume value is calculated by conversion of the captured drop images to a volume measurement. The average single drop volume value is used to calculate a total number of drops necessary to apply a desired amount of coating. Alternately, material is applied and the amount of material deposited is accumulated and adjustments are made to deposit only a desired amount of coating material. A drop volume is determined for either every drop or a sampling of drops as the drops are being applied. Adjustments to the coating process include changing drop size and changing a number of drops to be deposited.
摘要翻译： 一种用于控制涂覆材料沉积到医疗装置上的方法和装置。 捕获飞行中物质滴的图像，通过将捕获的液滴图像转换为体积测量来计算平均单滴体积值。 平均单滴体积值用于计算施加所需量涂层所需的总滴数。 或者，施加材料并且堆积的材料的量被累积并且进行调整以仅沉积所需量的涂层材料。 随着液滴的应用，每滴滴或液滴的取样确定液滴体积。 对涂布过程的调整包括改变液滴尺寸和改变要沉积的液滴数量。
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公开(公告)号：US07709048B2
公开(公告)日：2010-05-04
申请号：US10982408
申请日：2004-11-05
申请人： Eyal Teichman , Avner Schrift
发明人： Eyal Teichman , Avner Schrift
CPC分类号： A61F2/82 , A61F2002/30322 , A61F2250/0026 , A61F2250/0067 , B05B12/122 , B05B13/0442 , B05C5/0216
摘要： A method and device, for use in an operating theater just prior to implantation, for selectively applying a medical coating to an implantable medical device. Disclosed is a device for use with a stent deployed on a catheter balloon configured to apply a medical coating of a desired thickness to the surface of the stent only. A drop-on-demand inkjet printing system in association with an optical scanning device is described. The device is further configured to apply a plurality of layered coats, each layered coat being of a different coating material, and if appropriate, different thickness and to coat a portion of the medical device as a function of its geometric configuration. The coating is applied by moving an applicator over the device in a path that is independent of the deposited coating pattern.
摘要翻译： 一种在植入之前用于手术室的方法和装置，用于选择性地将医用涂层施加到可植入医疗装置上。 公开了一种用于与部署在导管球囊上的支架一起使用的装置，所述支架被构造成仅将所需厚度的医用涂层施加到支架的表面。 描述了与光学扫描装置相关联的按需喷墨打印系统。 该装置还被配置为施加多个分层涂层，每个分层涂层是不同的涂层材料，并且如果适当，施加不同的厚度并且根据其几何构型涂覆医疗装置的一部分。 通过在与沉积的涂层图案无关的路径中将涂布器移动到装置上来施加涂层。
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5.发明授权Lighting and imaging system including a flat light source with LED illumination 有权照明和成像系统包括带有LED照明的平面光源公开(公告)号：US07599727B2
公开(公告)日：2009-10-06
申请号：US11227767
申请日：2005-09-15
申请人： Eyal Teichman , Avner Schrift
发明人： Eyal Teichman , Avner Schrift
CPC分类号： G01N21/8806 , A61F2/82 , G01N21/95 , G01N21/9515 , G01N21/952 , G01N21/954 , G01N21/956 , G01N2021/8812 , G01N2021/8825 , G01N2021/8832 , G01N2021/8887 , G01N2201/021 , G01N2201/0633 , G01N2201/0634 , G01N2201/0636
摘要： A system for lighting a stent, i.e., providing an illumination source, to facilitate the capturing of an image of the stent. The lighting is provided so that an image capturing device, e.g., a digital camera or system, will capture an image that distinctly shows the difference between the stent and any surface upon which the stent is mounted, in addition to sharply defining the edges of the stent struts.
摘要翻译： 一种用于照明支架的系统，即提供照明源，以便于捕获支架的图像。 提供照明，使得诸如数字照相机或系统的图像捕获装置将捕获明显地显示支架和安装支架的任何表面之间的差异的图像，除了明确地限定 支架支柱
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公开(公告)号：US20060073265A1
公开(公告)日：2006-04-06
申请号：US10982408
申请日：2004-11-05
申请人： Eyal Teichman , Avner Schrift
发明人： Eyal Teichman , Avner Schrift
CPC分类号： A61F2/82 , A61F2002/30322 , A61F2250/0026 , A61F2250/0067 , B05B12/122 , B05B13/0442 , B05C5/0216
摘要： A method and device, for use in an operating theater just prior to implantation, for selectively applying a medical coating to an implantable medical device. Disclosed is a device for use with a stent deployed on a catheter balloon configured to apply a medical coating of a desired thickness to the surface of the stent only. A drop-on-demand inkjet printing system in association with an optical scanning device is described. The device is further configured to apply a plurality of layered coats, each layered coat being of a different coating material, and if appropriate, different thickness and to coat a portion of the medical device as a function of its geometric configuration. The coating is applied by moving an applicator over the device in a path that is independent of the deposited coating pattern.
摘要翻译： 一种在植入之前用于手术室的方法和装置，用于选择性地将医用涂层施加到可植入医疗装置上。 公开了一种用于与部署在导管球囊上的支架一起使用的装置，所述支架被构造成仅将所需厚度的医用涂层施加到支架的表面。 描述了与光学扫描装置相关联的按需喷墨打印系统。 该装置还被配置为施加多个分层涂层，每个分层涂层是不同的涂层材料，并且如果适当，施加不同的厚度并且根据其几何构型涂覆医疗装置的一部分。 通过在与沉积的涂层图案无关的路径中将涂布器移动到装置上来施加涂层。
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7.发明授权Method and system for coating a medical device using optical drop volume verification 有权使用光学液滴体积验证涂覆医疗器械的方法和系统公开(公告)号：US08381676B2
公开(公告)日：2013-02-26
申请号：US12826059
申请日：2010-06-29
申请人： Eyal Teichman , Avner Schrift
发明人： Eyal Teichman , Avner Schrift
IPC分类号： B05B7/00 , B05B13/02 , B05B13/04 , B05B9/06 , B05B3/00 , B05B15/04 , B05C15/00 , B05C5/00 , B05C11/00
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/91525 , A61F2002/91533 , A61F2002/91575 , A61F2230/0054 , B05B12/082 , B05B13/0442
摘要： A method and apparatus for controlling coating material deposition on to a medical device. Images of material drops in flight are captured and an average single drop volume value is calculated by conversion of the captured drop images to a volume measurement. The average single drop volume value is used to calculate a total number of drops necessary to apply a desired amount of coating. Alternately, material is applied and the amount of material deposited is accumulated and adjustments are made to deposit only a desired amount of coating material. A drop volume is determined for either every drop or a sampling of drops as the drops are being applied. Adjustments to the coating process include changing drop size and changing a number of drops to be deposited.
摘要翻译： 一种用于控制涂覆材料沉积到医疗装置上的方法和装置。 捕获飞行中物质滴的图像，通过将捕获的液滴图像转换为体积测量来计算平均单滴体积值。 平均单滴体积值用于计算施加所需量涂层所需的总滴数。 或者，施加材料并且堆积的材料的量被累积并且进行调整以仅沉积所需量的涂层材料。 随着液滴的应用，每滴滴或液滴的取样确定液滴体积。 对涂布过程的调整包括改变液滴尺寸和改变要沉积的液滴数量。
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8.发明申请Lighting and imaging system including a flat light source with led illumination 有权照明和成像系统包括带有LED照明的平面光源公开(公告)号：US20070073134A1
公开(公告)日：2007-03-29
申请号：US11227767
申请日：2005-09-15
申请人： Eyal Teichman , Avner Schrift
发明人： Eyal Teichman , Avner Schrift
IPC分类号： A61B5/05
CPC分类号： G01N21/8806 , A61F2/82 , G01N21/95 , G01N21/9515 , G01N21/952 , G01N21/954 , G01N21/956 , G01N2021/8812 , G01N2021/8825 , G01N2021/8832 , G01N2021/8887 , G01N2201/021 , G01N2201/0633 , G01N2201/0634 , G01N2201/0636
摘要： A system for lighting a stent, i.e., providing an illumination source, to facilitate the capturing of an image of the stent. The lighting is provided so that an image capturing device, e.g., a digital camera or system, will capture an image that distinctly shows the difference between the stent and any surface upon which the stent is mounted, in addition to sharply defining the edges of the stent struts.
摘要翻译： 一种用于照明支架的系统，即提供照明源，以便于捕获支架的图像。 提供照明，使得诸如数字照相机或系统的图像捕获装置将捕获明显地显示支架和安装支架的任何表面之间的差异的图像，除了明确地限定 支架支柱
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公开(公告)号：US20060172060A1
公开(公告)日：2006-08-03
申请号：US11047282
申请日：2005-01-31
申请人： Eyal Teichman , Avner Schrift
发明人： Eyal Teichman , Avner Schrift
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/91525 , A61F2002/91533 , A61F2002/91575 , A61F2230/0054 , B05B12/082 , B05B13/0442
摘要： A method and apparatus for controlling coating material deposition on to a medical device. Images of material drops in flight are captured and an average single drop volume value is calculated by conversion of the captured drop images to a volume measurement. The average single drop volume value is used to calculate a total number of drops necessary to apply a desired amount of coating. Alternately, material is applied and the amount of material deposited is accumulated and adjustments are made to deposit only a desired amount of coating material. A drop volume is determined for either every drop or a sampling of drops as the drops are being applied. Adjustments to the coating process include changing drop size and changing a number of drops to be deposited.
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公开(公告)号：US08104427B2
公开(公告)日：2012-01-31
申请号：US12534667
申请日：2009-08-03
CPC分类号： B05C5/0216 , B05B12/12 , B05B13/0442
摘要： The present invention is a method and device, which is suitable for use in an operating theater just prior to implantation, for selectively applying a medical coating to an implantable medical device, for example a stent. Disclosed is a device for use with a stent deployed on a catheter balloon. The device is configured to apply a medical coating of a desired thickness to the surface of a stent only. This is done by use of a drop-on-demand inkjet printing system in association with an optical scanning device. The device is further configured so as to, if necessary, apply a plurality of layered coats, each layered coat being of a different coating material, and if appropriate, different thickness. The section of the housing in which the stent is held during the coating procedure is detachable from the housing base. The detachable housing section may be easily cleaned and re-sterilized or simply disposed or simply disposed of.
摘要翻译： 本发明是适于在植入之前适用于手术室中的方法和装置，用于选择性地将医用涂层施加到可植入医疗装置，例如支架上。 公开了一种与部署在导管气囊上的支架一起使用的装置。 该装置被配置成将仅具有所需厚度的医用涂层施加到支架的表面。 这通过使用与光学扫描装置相关联的按需喷墨打印系统来完成。 该装置进一步构造成如果需要，施加多个分层涂层，每个分层涂层是不同的涂层材料，并且如果合适的话，其厚度不同。 支架在涂覆过程中保持的壳体的部分可从壳体基座拆卸。 可拆卸的壳体部分可以容易地清洁和重新灭菌或简单地设置或简单地处理。
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