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1.
公开(公告)号:US20240361232A1
公开(公告)日:2024-10-31
申请号:US18648345
申请日:2024-04-27
Applicant: Cerillo, INC
Inventor: Andrew Homyk , Kevin Seitter , Daniel Carrier, JR. , Sydney DeCleene , Sruthi Gopinathan
IPC: G01N21/01
CPC classification number: G01N21/01 , G01N2201/0633
Abstract: Herein are described a solid-state quasi-collimation stack and system containing the same. Also are described methods for narrow beamforming of electromagnetic radiation intended for the measurement of fluid samples. The solid-state quasi collimation stack typically comprises multiple layers of electromagnetic radiation blocking and absorbing components that selectively allow the passage of near-parallel electromagnetic beams.
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2.
公开(公告)号:US12076724B2
公开(公告)日:2024-09-03
申请号:US16998040
申请日:2020-08-20
Applicant: SYSMEX CORPORATION
Inventor: Kazuhiro Yamada , Kazuki Asao , Keisuke Kuwano
CPC classification number: B01L3/5085 , B01L9/06 , G01N21/01 , G01N21/6428 , G01N21/85 , G01N33/4915 , B01L2200/025 , B01L2200/143 , B01L2300/0627 , G01N2021/6439 , G01N2201/06113 , G01N2201/0633 , G01N2201/0636
Abstract: A specimen processing apparatus performs processing on a specimen contained in a container. The specimen processing apparatus includes: holders having different shapes, each of the holders being configured to hold the container; a holder placement unit that comprises holder receiving portions having different shapes, the shapes of the holder receiving portions corresponding to the shapes of the holders; and a specimen processing unit that performs processing on the specimen contained in the container held by one of the holders placed on the holder placement unit.
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3.
公开(公告)号:US12050177B2
公开(公告)日:2024-07-30
申请号:US18203359
申请日:2023-05-30
Applicant: Opsolution GMBH
Inventor: Bjoern Magnussen , Claudius Stern , Wolfgang Koecher
IPC: G01N21/49 , A61B5/145 , A61B5/1455 , G01N21/47 , G01N21/17
CPC classification number: G01N21/49 , A61B5/14546 , A61B5/1455 , G01N21/474 , G01N21/4795 , A61B5/14532 , A61B2560/0223 , A61B2562/046 , G01N2021/1782 , G01N2021/4752 , G01N2201/06153 , G01N2201/0621 , G01N2201/0626 , G01N2201/0633 , G01N2201/066 , G01N2201/1211 , G01N2201/1214
Abstract: A device for optical detection of analytes in a sample includes at least two optoelectronic components. The optoelectronic components include at least one optical detector configured to receive a photon and at least one optical emitter configured to emit a photon. The at least one optical emitter includes at least three optical emitters disposed in a flat, non-linear arrangement, and the at least one optical detector includes at least three optical detectors disposed in a flat, non-linear arrangement. The at least three optical emitters and the at least three optical detectors include at least three different wavelength characteristics.
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公开(公告)号:US20240133814A1
公开(公告)日:2024-04-25
申请号:US18458988
申请日:2023-08-30
Applicant: Robert R. Alfano
Inventor: Robert R. Alfano , Sandra Mamani Reyes
IPC: G01N21/65
CPC classification number: G01N21/65 , G01N2201/06113 , G01N2201/0633
Abstract: A method for obtaining a polarized orbital angular momentum Raman spectrum using vector vortex beams, includes the steps of emitting a polarized laser light from a laser source. The polarized laser light is passed through a narrow band filter that is then passed through a section of wave plates (quarter or half wave plate) to generate polarized light (linear, circular, radial and azimuthal), then through a q-plate (vortex retarder or spiral plate) to give a vortex structure topology carrying orbital angular momentum with a helical phase. The polarized vector vortex light is then directed to contact a sample, thereby producing a Raman scatter beam. The Raman scatter beam is passed back and collected into a spectrometer, thereby obtaining a Raman scattering spectrum of the sample to investigate the matching of the multipoles of the material and the multipoles of the light. A method for transmission with Multiple expansions of orbital angular momentum in rat cerebellum tissue is also disclosed. In general, we use polarized Laguerre-Gaussian vector vortex beams as a topology multipole model to describe and study the light matter interaction for Raman and transmission using the fact that the optical vortices and material can possess Multipoles denoted as L in form of monopole (L=0), dipole (L=1), quadrupole (L=2), octupole (L=3), hexidecapole (L=4) and higher orders. These multipoles can be involved with the matching up with the symmetry of the moments involved with vibrational states in Raman processes.
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公开(公告)号:US20240102936A1
公开(公告)日:2024-03-28
申请号:US18373436
申请日:2023-09-27
Applicant: Yokogawa Electric Corporation
Inventor: Kodai Murayama
IPC: G01N21/85
CPC classification number: G01N21/85 , G01N2201/0633 , G01N2201/0636 , G01N2201/0638
Abstract: An optical device 1 includes: an optical element block 10 including optical elements that form an optical path P of light used for optical measurement, arranged around a measurement subject S so that the optical path P intersects the measurement subject S; and a rotation mechanism 20 configured to change an angle of the optical element block 10 relative to the measurement subject S so that the total length of the portion of the optical path P coincident with the measurement subject S changes.
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公开(公告)号:US11892409B1
公开(公告)日:2024-02-06
申请号:US17973285
申请日:2022-10-25
Applicant: Taiwan RedEye Biomedical Inc.
Inventor: Tsung-Jui Lin , Shuo-Ting Yan , Kuan-Wei Su
CPC classification number: G01N21/65 , G01J1/42 , G01N2201/0633
Abstract: The present invention includes a shell, a light emitter, a beam splitter, a convergent lens, an optical filter, a collimation unit, a discrete light detection unit, and a processing unit. The shell includes a sample well to contain a sample. The light emitter generates a detection beam towards the beam splitter, the detection beam is reflected by the beam splitter before being converged by the convergent lens onto the sample, and a Raman scattered beam is scattered from the sample. The Raman scattered beam respectively passes through the convergent lens, the beam splitter, the optical filter, and the collimation unit, allowing the collimation unit to collimate the Raman scattered beam into a collimated beam. The discrete light detection unit generates multiple light intensity signals according to the collimated beam received, and the processing unit generates a detection result according to the light intensity signals to help detect toxins.
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公开(公告)号:US11892397B2
公开(公告)日:2024-02-06
申请号:US17316467
申请日:2021-05-10
Inventor: Jing Yong Ye , Jonathan D. Scudder
IPC: G01N21/31
CPC classification number: G01N21/31 , G01N2201/0633 , G01N2201/0636 , G01N2201/0638 , G01N2201/06113 , G01N2201/08
Abstract: A pyrogenicity test method and assay of endotoxins allows for rapid and ultrahigh sensitivity testing of parenteral pharmaceuticals or medical devices that contact blood or cerebrospinal fluid by employing a Limulus Amoebocyte Lysate (LAL) assay monitored with a photonic-crystal biosensor. The photonic-crystal biosensor is capable of determining the presence of endotoxins in a test sample by detecting shifts in the resonant condition of an open microcavity affected by the changes in the refractive index of the analyte solutions used.
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公开(公告)号:US20230204515A1
公开(公告)日:2023-06-29
申请号:US18087341
申请日:2022-12-22
Applicant: HORIBA INSTRUMENTS INCORPORATED
Inventor: Nicolas VEZARD , Beth FINAMORE , Aashish TULADHAR
CPC classification number: G01N21/65 , G01N21/6428 , G01N2201/06113 , G01N2201/0633 , G01N2201/0636 , G01N2201/08 , G01N2201/0635 , G01N2201/127
Abstract: A microplate reader simultaneously obtains Raman measurements from samples contained in non-adjacent wells. At least two Raman probes are positioned perpendicularly above or below the microplate to simultaneously acquire Raman spectra data of the non-adjacent liquid samples. Each probe is coupled to a laser and a spectrometer and includes a lens focusing laser light within the sample and collecting light from the sample for the spectrometer. The spectrometer may include a 2D imaging sensor (sCMOS or CCD) to image light from multiple probes simultaneously, spaced from one another to reduce crosstalk. A positioner moves the microplate plate or probes to acquire data from a different subset of non-adjacent samples, and may also vary laser focus within wells during data acquisition. Multiple fluorescence probes may simultaneously acquire fluorescence data from the same samples, or non-adjacent samples. Probes may be fiber-coupled and positioned within a reaction chamber of a liquid handling system.
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公开(公告)号:US20190017993A1
公开(公告)日:2019-01-17
申请号:US16133002
申请日:2018-09-17
Applicant: Nova Biomedical Corporation
Inventor: Michael S. Cafferty , Scott P. Cionek
CPC classification number: G01N33/49 , G01J3/0202 , G01J3/0205 , G01J3/0208 , G01J3/0218 , G01J3/0286 , G01J3/0291 , G01J3/0297 , G01J3/10 , G01J3/14 , G01J3/28 , G01J3/42 , G01J2003/2866 , G01N21/0303 , G01N21/255 , G01N21/274 , G01N21/31 , G01N33/492 , G01N2021/0321 , G01N2021/0389 , G01N2201/062 , G01N2201/0633 , G01N2201/0634 , G01N2201/0638
Abstract: An optical component group for use in a spectrometer module of a system for measuring whole-blood hemoglobin parameters or whole-blood bilirubin parameters. The optical component group includes a light dispersing element and an achromatic lens assembly disposed between the light dispersing element and a light entrance port of the spectrometer module where the achromatic lens assembly is thermo-compensating permitting thermal expansion and contraction of the achromatic lens assembly in a linear direction where the linear directions is also transverse to a light beam from the light entrance port through the achromatic lens assembly and to the light dispersing element and back through the achromatic lens assembly.
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公开(公告)号:US20180341096A1
公开(公告)日:2018-11-29
申请号:US16053533
申请日:2018-08-02
Applicant: The United States of America, as represented by Secretary, Depart. of Health and Human Services
Inventor: Hari Shroff , Andrew York
IPC: G02B21/00
CPC classification number: G02B21/0072 , G01N21/6458 , G01N2021/6478 , G01N2201/0633 , G02B21/0032 , G02B21/0036 , G02B21/004 , G02B21/0076
Abstract: A multi-focal structured illumination microscopy (SIM) system for generating multi-focal patterns of a sample is disclosed. The multi-focal SIM system performs a focusing, scaling and summing operation on each multi-focal pattern in a sequence of multi-focal patterns that completely scan the sample to produce a high resolution composite image.
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