公开(公告)号：US10100340B2

公开(公告)日：2018-10-16

申请号：US15301091

申请日：2015-04-03

Applicant: FERMENTALG

Inventor： Pierre Calleja ,  Julien Pagliardini ,  Olivier Cagnac ,  Francois Godart

IPC: C12N1/12 ,  C12P7/64 ,  A23D9/00 ,  C11B1/10 ,  A23K20/158 ,  A23K50/80 ,  A23L33/115

Abstract: A method for culturing a protist of the Aurantiochytrium mangrovei genus. The genus is characterized genetically and by virtue of the lipid profile thereof. The method makes it possible to obtain a high biomass yield and a lipid, and more particularly docosahexaenoic acid (DHA), enrichment of the protists thus cultured. The development of a culture medium allows the production, at high cell density, of a DHA-rich protest of the Aurantiochytrium mangrovei genus. The medium is chemically defined at low sodium ion (Na+) and chloride ion (Cl−) content.

公开(公告)号：US09556468B2

公开(公告)日：2017-01-31

申请号：US14385305

申请日：2013-03-15

Applicant: FERMENTALG

Inventor： Khadidja Romari ,  Francois Godart ,  Pierre Calleja

IPC: C12P23/00 ,  C12R1/89 ,  C12N1/12

CPC classification number: C12R1/89 ,  C12N1/12 ,  C12P23/00

Abstract: Novel strains of microalgae belonging to the Scenedesmus genus enable the production of lipids, in particular lutein, in mixotrophic mode, as well as a method for selecting and culturing the strains using a variable and/or discontinuous supply of light, in particular in the form of flashes.

Abstract translation: 属于Scenedesmus属的新型微藻菌株能够以混合营养模式生产脂质，特别是叶黄素，以及使用可变和/或不连续光供应来选择和培养菌株的方法，特别是以形式 的闪光。

公开(公告)号：US20150037839A1

公开(公告)日：2015-02-05

申请号：US14385305

申请日：2013-03-15

Applicant: FERMENTALG

Inventor： Khadidja Romari ,  Francois Godart ,  Pierre Calleja

IPC: C12P23/00 ,  C12R1/89 ,  C12N1/12

CPC classification number: C12R1/89 ,  C12N1/12 ,  C12P23/00

Abstract: Novel strains of microalgae belonging to the Scenedesmus genus enable the production of lipids, in particular lutein, in mixotrophic mode, as well as a method for selecting and culturing the strains using a variable and/or discontinuous supply of light, in particular in the form of flashes.

Abstract translation: 属于Scenedesmus属的新型微藻菌株能够以混合营养模式生产脂质，特别是叶黄素，以及使用可变和/或不连续光供应来选择和培养菌株的方法，特别是以形式 的闪光。

公开(公告)号：US10597630B2

公开(公告)日：2020-03-24

申请号：US15506377

申请日：2015-08-26

Applicant: FERMENTALG

Inventor： Pierre Calleja ,  Cyril Rols ,  Julien Pagliardini ,  Brice Bourdenx

IPC: C12N1/12 ,  C12P7/64

Abstract: Disclosed is a method for culture of microalgae, advantageously of the genus Crypthecodinium having a gene coding for the small 18s ribosomal RNA subunit having a genetic similarity of at least 96% with the same gene of the strain of the species Crypthecodinium cohnii deposited in the CCAP (Culture Collection of Algae and Protozoa) under number CCAP 1104/3 in a defined chemical medium.

公开(公告)号：US10100345B2

公开(公告)日：2018-10-16

申请号：US14904369

申请日：2014-07-15

Applicant: FERMENTALG

Inventor： Francois Godart ,  Julien Pagliardini ,  Cyril Rols ,  Pierre Calleja

IPC: C12N1/12 ,  C12P23/00 ,  C12R1/89 ,  C12N13/00 ,  C12P7/64

Abstract: Disclosed are novel strains of protists belonging to the Aurantiochytrium genus that allow the high yield production of lipids and carotenoids, in particular docosahexaenoic acid (DHA) and canthaxanthin and/or astaxanthin, in mixotrophic mode, in particular, using variable and/or discontinuous provision of light, in particular in the form of flashes.

公开(公告)号：US20180265835A1

公开(公告)日：2018-09-20

申请号：US15882241

申请日：2018-01-29

Applicant: FERMENTALG

Inventor： Khadidja Romari ,  François Godart ,  Pierre Calleja

IPC: C12N1/12 ,  C12N13/00 ,  C12P23/00 ,  C12R1/89 ,  C12P7/64

CPC classification number: C12N1/12 ,  C12N13/00 ,  C12P7/6427 ,  C12P7/6472 ,  C12P23/00 ,  C12R1/89

Abstract: New strains of microalgae belonging to the Nitzschia genus allow high-yield production of lipids such as docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), and/or carotenoids such as fucoxanthin. Biomass containing the microalgae can be charged with fucoxanthin representing more than 0.2% by weight of the dry matter.

公开(公告)号：US20150044738A1

公开(公告)日：2015-02-12

申请号：US14385507

申请日：2013-03-15

Applicant: FERMENTALG

Inventor： Khadidja Romari ,  Pierre Calleja

IPC: C12P7/64 ,  C12R1/89

CPC classification number: C12P7/6427 ,  C12N1/12 ,  C12P7/6472 ,  C12R1/89

Abstract: New strains of microalgae belonging to the Euglena genus, allow production of lipids, in particular of EPA and/or ARA, in mixotrophic mode, and a method for selecting and culturing such strains, using a variable and/or discontinuous light source, in particular a flashing light.

Abstract translation: 属于欧氏弧菌属的微藻的新菌株允许在混合营养模式下产生脂质，特别是EPA和/或ARA，以及使用可变和/或不连续光源特别选择和培养这些菌株的方法 闪烁的光芒

公开(公告)号：US09938545B2

公开(公告)日：2018-04-10

申请号：US14906056

申请日：2014-07-21

Applicant: FERMENTALG ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) ,  COMMISARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES

Inventor： Pierre Calleja ,  Marina Leterrier ,  Eric Marechal

IPC: C12P7/64 ,  C12N1/12 ,  C12N15/82 ,  C12N15/74 ,  C12P19/34 ,  C12N9/14 ,  C12N9/10

CPC classification number: C12P7/6463 ,  C12N1/12 ,  C12N9/1029 ,  C12N9/14 ,  C12N15/82 ,  C12Y203/01051

Abstract: The present invention relates to a genetically engineered algae strain in which the expression of the CGI-58 gene or homologous gene thereof is silenced. The present invention further relates to a method of triacylglycerol accumulation using said genetically engineered diatom and/or diatom strain.

公开(公告)号：US09506100B2

公开(公告)日：2016-11-29

申请号：US14385294

申请日：2013-03-15

Applicant: FERMENTALG

Inventor： Khadidja Romari ,  Adeline Le Monnier ,  Cyril Rols ,  Cindy Merlet ,  Julien Pagliardini ,  Pierre Calleja ,  Claude Gudin

IPC: C12P7/64 ,  C12P23/00 ,  C12R1/89 ,  C12N1/12

CPC classification number: C12P23/00 ,  C12N1/12 ,  C12P7/6427 ,  C12P7/6472 ,  C12R1/89

Abstract: New strains of protists belonging to the Schizochytrium genus, allow high-yield production of lipids and carotenoids, in particular of astaxanthin and docosahexaenoic acid (DHA), in mixotrophic mode, and a method for selecting and culturing such strains, using a variable and/or discontinuous light source, in particular a flashing light.

Abstract translation: 属于裂殖壶菌属的新生原子生产菌株允许以混合营养模式高产量生产脂质和类胡萝卜素，特别是虾青素和二十二碳六烯酸（DHA），以及选择和培养这些菌株的方法，使用变量和/ 或不连续光源，特别是闪光灯。

公开(公告)号：US20150037838A1

公开(公告)日：2015-02-05

申请号：US14385294

申请日：2013-03-15

Applicant: FERMENTALG

Inventor： Khadidja Romari ,  Adeline Le Monnier ,  Cyril Rols ,  Cindy Merlet ,  Julien Pagliardini ,  Pierre Calleja ,  Claude Gudin

IPC: C12P23/00 ,  C12R1/89 ,  C12P7/64 ,  C12N1/12

CPC classification number: C12P23/00 ,  C12N1/12 ,  C12P7/6427 ,  C12P7/6472 ,  C12R1/89

Abstract: New strains of protists belonging to the Schizochytrium genus, allow high-yield production of lipids and carotenoids, in particular of astaxanthin and docosahexaenoic acid (DHA), in mixotrophic mode, and a method for selecting and culturing such strains, using a variable and/or discontinuous light source, in particular a flashing light.

Abstract translation: 属于裂殖壶菌属的新生原子生产菌株允许以混合营养模式高产量生产脂质和类胡萝卜素，特别是虾青素和二十二碳六烯酸（DHA），以及选择和培养这些菌株的方法，使用可变和/ 或不连续光源，特别是闪光灯。