公开(公告)号：US20240279693A1

公开(公告)日：2024-08-22

申请号：US18570268

申请日：2022-07-01

申请人： FMC Agricultural Solutions A/S ,  BIOPHERO APS

发明人： Carina Holkenbrink ,  Irina Borodina

IPC分类号： C12P7/6427 ,  C12N9/02

CPC分类号： C12P7/6427 ,  C12N9/0008 ,  C12N9/0071 ,  C12Y102/0105 ,  C12Y114/19 ,  C12Y114/19006

摘要： The present invention relates to yeast cells capable of producing Δ(12) desaturated fatty acyl-CoAs and optionally fatty alcohols, said yeast cells expressing heterologous Δ(12) desaturases capable of introducing a double bond at position (12), i. e. a double bond between the carbon at position (12) and the carbon at position (13), in a saturated or desaturated fatty acyl-CoA having a carbon chain length of at least (13).

公开(公告)号：US20240327874A1

公开(公告)日：2024-10-03

申请号：US17783955

申请日：2020-12-18

申请人： FMC Agricultural Solutions A/S

发明人： Irina Borodina ,  Carina Holkenbrink ,  Christer Löfstedt ,  Baojian Ding ,  Leonie Wenning

IPC分类号： C12P7/04 ,  C12N9/02 ,  C12N9/10 ,  C12N9/16 ,  C12P7/64 ,  C12P7/6409

CPC分类号： C12P7/04 ,  C12N9/0008 ,  C12N9/004 ,  C12N9/1029 ,  C12N9/16 ,  C12P7/64 ,  C12P7/6409 ,  C12Y102/01084 ,  C12Y106/02002 ,  C12Y203/01086

摘要： The present invention relates to yeast cells engineered for the production of E8,E10-dodecadienyl coenzyme A, codlemone (E8,E10-dodecadien-1-ol), and optionally its derivatives E8,E10-dodecadienyl acetate and/or E8,E10-dodecadienal. Methods for production of E8,E10-dodecadienyl coenzyme A, codlemone (E8,E10-do-decadien-1-ol), and optionally its derivatives E8,E10-dodecadienyl acetate and/or E8,E10-dodecadienal are also provided. Nucleic acid constructs useful for obtaining such yeast cells are also provided.

公开(公告)号：US20240287555A1

公开(公告)日：2024-08-29

申请号：US18570271

申请日：2022-07-01

申请人： FMC Agricultural Solutions A/S

发明人： Carina Holkenbrink ,  Irina Borodina ,  Baojian Ding ,  Christer Löfstedt

IPC分类号： C12P7/6409 ,  C12N9/02 ,  C12P7/6436

CPC分类号： C12P7/6409 ,  C12N9/0008 ,  C12N9/0071 ,  C12P7/6436 ,  C12Y102/01084 ,  C12Y114/19 ,  C12Y114/19005

摘要： The present invention relates to yeast cells capable of producing Δ13 desaturated fatty acyl-CoAs and optionally desaturated fatty alcohols, said yeast cells expressing heterologous Δ13 desaturases. Said compounds are precursors of sex pheromone components of several insects, such as the navel orangeworm Amyelois transitella, the grape leaffolder Desmia funeralis, Cedar processionary moth Thaumetopoea bonjeani, the iron prominent Notodonta dromedarius, and others.