公开(公告)号：US20240139256A1

公开(公告)日：2024-05-02

申请号：US18479774

申请日：2023-10-02

Applicant: FUJIFILM Cellular Dynamics, Inc. ,  FUJIFILM Holdings America Corporation

Inventor： Sarah HIMMERICH ,  Nathaniel BEARDSLEY ,  Annie ARMSTRONG SMELTER ,  Nathan MEYER ,  Ravi VAIDYANATHAN ,  Cara RIEGER

IPC: A61K35/33 ,  A61P9/04 ,  C12N5/071 ,  C12N5/077

CPC classification number: A61K35/33 ,  A61P9/04 ,  C12N5/0657 ,  C12N5/0697 ,  C12N2501/115 ,  C12N2501/155 ,  C12N2501/16 ,  C12N2501/415 ,  C12N2506/45

Abstract: Provided herein are methods for producing quiescent cardiac fibroblast cells from pluripotent stem cells. Further provided herein are microtissue compositions comprising the cardiac fibroblast cells with endothelial cells and cardiomyocytes.

公开(公告)号：US20250011714A1

公开(公告)日：2025-01-09

申请号：US18886115

申请日：2024-09-16

Applicant: FUJIFILM Cellular Dynamics, Inc.

Inventor： Nathan MEYER ,  Lucas CHASE ,  Casey STANKEWICZ

IPC: C12N5/00 ,  C12N5/079

Abstract: Provided herein are methods of enriching a retinal pigment epithelium (RPE) cell population derived from stem cells. Such a method may comprise removing contaminating cells through the depletion of CD24 positive cells, CD56 positive cells, and/or CD90 positive cells from a starting population of RPE cells.

公开(公告)号：US20220033770A1

公开(公告)日：2022-02-03

申请号：US17493533

申请日：2021-10-04

Applicant: FUJIFILM Cellular Dynamics, Inc.

Inventor： Nathan MEYER ,  Lucas CHASE ,  Casey STANKEWICZ

IPC: C12N5/00 ,  C12N5/079

Abstract: Provided herein are methods of enriching a retinal pigment epithelium (RPE) cell population derived from stem cells. Such a method may comprise removing contaminating cells through the depletion of CD24 positive cells, CD56 positive cells, and/or CD90 positive cells from a starting population of RPE cells.

公开(公告)号：US20210238546A1

公开(公告)日：2021-08-05

申请号：US17049018

申请日：2019-04-22

Applicant: FUJIFILM Cellular Dynamics, Inc.

Inventor： Lucas CHASE ,  Kyle WALLACE ,  Benjamin MELINE ,  Andrew DIAS ,  Brandon SHELLEY ,  Marisa FENN ,  Debjani PHILLIPS ,  Matthew STERNFELD ,  Nathan MEYER

IPC: C12N5/079 ,  A61K35/30 ,  C12N5/0793 ,  G01N33/68

Abstract: Provided herein are methods of producing a photoreceptor precursor (PRP) cell population derived from stem cells. Further provided herein are methods of using the PRP cell populations, such as for therapeutics.