公开(公告)号：US20190093131A1

公开(公告)日：2019-03-28

申请号：US15772567

申请日：2016-11-07

Applicant: Firmenich SA

Inventor： Eric Wen-Bo LIU ,  Xiu-Feng HE ,  Olivier HAEFLIGER ,  Zong-Xia YU ,  Pan LI

IPC: C12P7/02

CPC classification number: C12P7/02 ,  C12N9/16 ,  C12P7/04 ,  C12Y301/07007

Abstract: The present invention discloses a method of producing drimenol and/or drimenol derivatives by contacting a polypeptide with farnesyl pyrophosphate. Also provided is an amino acid sequence of a polypeptide useful in the methods of the invention and nucleic acid encoding the polypeptides of the invention. The method further provides host cells or organisms genetically modified to express the polypeptides of the invention and useful to produce drimenol and/or drimenol derivatives.

公开(公告)号：US20180094281A1

公开(公告)日：2018-04-05

申请号：US15564671

申请日：2016-04-11

Applicant: Firmenich SA

Inventor： Michel SCHALK ,  Fabienne DEGUERRY ,  Pan LI ,  Xiufeng HE ,  Qi WANG

IPC: C12P5/00 ,  C12N9/88

CPC classification number: C12P5/007 ,  C12N9/88 ,  C12Y402/03039 ,  C12Y402/03079

Abstract: Provided herein is an isolated polypeptide from Juniperus virginiana, Platycladus orientalis ‘Beverleyensis’ or Platycladus orientalis comprising a (+)-cedrol or a (−)-thujopsene synthase. Further provided herein is an isolated nucleic acid molecule from Juniperus virginiana, Platycladus orientalis ‘Beverleyensis’ or Platycladus orientalis encoding a (+)-cedrol or (−)-thujopsene synthase. Further provided herein are methods of producing (+)-cedrol or (−)-thujopsene.