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公开(公告)号:US20170181970A1
公开(公告)日:2017-06-29
申请号:US15349240
申请日:2016-11-11
发明人: Dov Tamarkin , Helena Shifrin , Rita Keynan , Enbal Ziv , Tal Berman , David Schuz , Elana Gazal
IPC分类号: A61K9/12 , A61K47/34 , A61K47/44 , A61K31/7056 , A61K31/355 , A61K31/59 , A61K31/522 , A61K31/20 , A61K31/65 , A61K47/14
CPC分类号: A61K9/12 , A61K8/046 , A61K9/0014 , A61K9/122 , A61K31/20 , A61K31/355 , A61K31/522 , A61K31/59 , A61K31/65 , A61K31/7056 , A61K45/06 , A61K47/06 , A61K47/14 , A61K47/24 , A61K47/34 , A61K47/44 , Y10S514/871 , Y10S514/945
摘要: A waterless foamable pharmaceutical composition suitable for external administration is disclosed. The composition includes a foamable carrier least one liquefied or compressed gas propellant. The foamable carrier includes at least one liquid oil; at least one silicone and at least one least one stabilizing agent; wherein the stabilizing agent selected from the group consisting of about 0.01% to about 25% by weight of at least one surface-active agent alone or on combination with a foam adjuvant; and about 0% to about 5% by weight of at least one polymeric agent alone or on combination with a foam adjuvant; and mixtures thereof. Pharmaceutical compositions comprising active agents, methods for their preparation, propellants suitable for use with the carriers and uses thereof are further described.
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公开(公告)号:US20150118164A1
公开(公告)日:2015-04-30
申请号:US14504942
申请日:2014-10-02
发明人: Dov Tamarkin , Helena Shifrin , Rita Keynan , Enbal Ziv , Tal Berman , David Schuz , Elana Gazal
CPC分类号: A61K9/12 , A61K8/046 , A61K9/0014 , A61K9/122 , A61K31/20 , A61K31/355 , A61K31/522 , A61K31/59 , A61K31/65 , A61K31/7056 , A61K45/06 , A61K47/06 , A61K47/14 , A61K47/24 , A61K47/34 , A61K47/44 , Y10S514/871 , Y10S514/945
摘要: A waterless foamable pharmaceutical composition suitable for external administration is disclosed. The composition includes a foamable carrier least one liquefied or compressed gas propellant. The foamable carrier includes at least one liquid oil; at least one silicone and at least one least one stabilizing agent; wherein the stabilizing agent selected from the group consisting of about 0.01% to about 25% by weight of at least one surface-active agent alone or on combination with a foam adjuvant; and about 0% to about 5% by weight of at least one polymeric agent alone or on combination with a foam adjuvant; and mixtures thereof. Pharmaceutical compositions comprising active agents, methods for their preparation, propellants suitable for use with the carriers and uses thereof are further described.
摘要翻译: 公开了一种适用于外用的无水可发泡药物组合物。 组合物包括可发泡载体至少一种液化或压缩气体推进剂。 可发泡载体包括至少一种液体油; 至少一种硅氧烷和至少一种至少一种稳定剂; 其中所述稳定剂选自约0.01%至约25%重量的至少一种表面活性剂单独或与泡沫佐剂组合; 和约0%至约5%重量的至少一种聚合物单体或与泡沫佐剂组合; 及其混合物。 进一步描述包含活性剂的药物组合物,其制备方法,适用于载体的推进剂及其用途。
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公开(公告)号:US20190091149A1
公开(公告)日:2019-03-28
申请号:US15999088
申请日:2018-08-17
发明人: Dov Tamarkin , Helena Shifrin , Rita Keynan , Enbal Ziv , Tal Berman , David Schuz , Elana Gazal
IPC分类号: A61K9/12 , A61K45/06 , A61K31/59 , A61K31/522 , A61K31/355 , A61K47/34 , A61K31/7056 , A61K47/44 , A61K8/04 , A61K9/00 , A61K31/65 , A61K47/06 , A61K47/14 , A61K47/24 , A61K31/20
摘要: A waterless foamable pharmaceutical composition suitable for external administration is disclosed. The composition includes a foamable carrier least one liquefied or compressed gas propellant. The foamable carrier includes at least one liquid oil; at least one silicone and at least one least one stabilizing agent; wherein the stabilizing agent selected from the group consisting of about 0.01% to about 25% by weight of at least one surface-active agent alone or on combination with a foam adjuvant; and about 0% to about 5% by weight of at least one polymeric agent alone or on combination with a foam adjuvant; and mixtures thereof. Pharmaceutical compositions comprising active agents, methods for their preparation, propellants suitable for use with the carriers and uses thereof are further described.
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公开(公告)号:US09549898B2
公开(公告)日:2017-01-24
申请号:US14504942
申请日:2014-10-02
发明人: Dov Tamarkin , Helena Shifrin , Rita Keynan , Enbal Ziv , Tal Berman , David Schuz , Elana Gazal
CPC分类号: A61K9/12 , A61K8/046 , A61K9/0014 , A61K9/122 , A61K31/20 , A61K31/355 , A61K31/522 , A61K31/59 , A61K31/65 , A61K31/7056 , A61K45/06 , A61K47/06 , A61K47/14 , A61K47/24 , A61K47/34 , A61K47/44 , Y10S514/871 , Y10S514/945
摘要: A waterless foamable pharmaceutical composition suitable for external administration is disclosed. The composition includes a foamable carrier least one liquefied or compressed gas propellant. The foamable carrier includes at least one liquid oil; at least one silicone and at least one least one stabilizing agent; wherein the stabilizing agent selected from the group consisting of about 0.01% to about 25% by weight of at least one surface-active agent alone or on combination with a foam adjuvant; and about 0% to about 5% by weight of at least one polymeric agent alone or on combination with a foam adjuvant; and mixtures thereof. Pharmaceutical compositions comprising active agents, methods for their preparation, propellants suitable for use with the carriers and uses thereof are further described.
摘要翻译: 公开了一种适用于外用的无水可发泡药物组合物。 组合物包括可发泡载体至少一种液化或压缩气体推进剂。 可发泡载体包括至少一种液体油; 至少一种硅氧烷和至少一种至少一种稳定剂; 其中所述稳定剂选自约0.01%至约25%重量的至少一种表面活性剂单独或与泡沫佐剂组合; 和约0%至约5%重量的至少一种聚合物单体或与泡沫佐剂组合; 及其混合物。 进一步描述包含活性剂的药物组合物,其制备方法,适用于载体的推进剂及其用途。
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