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1.发明申请Method and apparatus for inducing controlled mechanical constraints in a tissue construct 失效用于在组织构建体中诱导受控机械约束的方法和装置公开(公告)号：US20050019897A1
公开(公告)日：2005-01-27
申请号：US10866708
申请日：2004-06-15
申请人： Francois Bergeron , Lucie Germain , Francois Auger
发明人： Francois Bergeron , Lucie Germain , Francois Auger
IPC分类号： C12M3/00
摘要： A method and a device (10) for reorganizing the fibers of a matrix in a living tissue sheet (S) by inducing controlled mechanical constraints in the living tissue (S) sheet thus causing the fibers of the matrix to be aligned parallel to the strain orientation. The sheet (S) is held in a stretched state until the fibers set in place.
摘要翻译： 一种方法和装置（10），用于通过在活组织（S）片中引起受控的机械约束来重新组织活组织片（S）中的基质的纤维，从而使基质的纤维平行于菌株 方向。 片材（S）保持在拉伸状态，直到纤维固定就位。
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公开(公告)号：US20050170501A1
公开(公告)日：2005-08-04
申请号：US10511433
申请日：2003-04-24
申请人： Francois Auger , Francois Bergeron , Lucie Germain
发明人： Francois Auger , Francois Bergeron , Lucie Germain
CPC分类号： C12N5/0691 , C12N5/0697 , C12N2502/1323 , C12N2502/28
摘要： The present invention relates to a method of assembling a single living tissue sheet formed of different cell populations. According to this invention at least two cell populations composing at least two living tissue sheets can be assembled into a single continuous tissue construct. The cells of this construct can also be autologous or heterologous depending on the needs and the type of implant to be transferred in a recipient patient.
摘要翻译： 本发明涉及组装由不同细胞群形成的单个活组织片的方法。 根据本发明，构成至少两个活组织片的至少两个细胞群可以组装成单个连续的组织构建体。 这种构建体的细胞也可以是自体的或异源的，这取决于在受体患者中要转移的植入物的需要和类型。
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公开(公告)号：US20070111307A1
公开(公告)日：2007-05-17
申请号：US11603865
申请日：2006-11-24
申请人： Francois Auger , Francois Bergeron , Lucie Germain
发明人： Francois Auger , Francois Bergeron , Lucie Germain
CPC分类号： C12N5/0691 , C12N5/0697 , C12N2502/1323 , C12N2502/28
摘要： The present invention relates to a method of assembling a single living tissue sheet formed of different cell populations. According to this invention at least two cell populations composing at least two living tissue sheets can be assembled into a single continuous tissue construct The cells of this construct can also be autologous or heterologous depending on the needs and the type of implant to be transferred in a recipient patient.
摘要翻译： 本发明涉及组装由不同细胞群形成的单个活组织片的方法。 根据本发明，构成至少两个活组织片的至少两个细胞群可以组装成单个连续组织构建体。该构建体的细胞也可以是自体的或异源的，这取决于待转移的植入物的需要和类型 受试者。
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公开(公告)号：US20060128010A1
公开(公告)日：2006-06-15
申请号：US10522010
申请日：2002-07-16
CPC分类号： C12N5/0062
摘要： A method for preparing a human or animal tissue by applying a compressive force to a stack of sheets of living tissue thereby inducing adjacent layers to fuse or adhere to each other. The force is applied in direction normal to the surface of the tissue. A multi-layer tissue produced by the method decribed above can also possess at least two different types of sheets and/or consist essentially of between two and twelve sheets of living tissue. The method can also be used to prepare a planar tissue that can further be incorporated in a multi-layer tissue construct. The methods and tissues described herein are useful for the preparation of engineered tissues.
摘要翻译： 一种通过向生物体组织堆叠施加压缩力来制备人或动物组织的方法，从而导致相邻层彼此熔合或粘附。 力沿垂直于组织表面的方向施加。 通过上述方法生产的多层组织也可以具有至少两种不同类型的片材和/或基本上由两片和12片生物组织组成。 该方法也可用于制备可以进一步掺入多层组织结构中的平面组织。 本文所述的方法和组织可用于制备工程组织。
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公开(公告)号：US20050079604A1
公开(公告)日：2005-04-14
申请号：US10495748
申请日：2002-11-27
申请人： Lucie Germain , Francois Auger , Guillaume Grenier , Danielle Larouche , Murielle Remy-Zolghadri , Francois Bergeron
发明人： Lucie Germain , Francois Auger , Guillaume Grenier , Danielle Larouche , Murielle Remy-Zolghadri , Francois Bergeron
CPC分类号： A61L27/3691 , A61L27/18 , A61L27/3604 , A61L27/60 , C12N5/0691 , C12N5/0698 , C12N2502/094 , C12N2502/1323 , C08L69/00
摘要： The present invention relates two new methods of improving the functionality of human or animal tissues by physically or biochemically treating the tissue prior to submitting it to different tests or before grafting it to a recipientpatient. Such a treated tissue is therefore rendered having a greater capability to resist to mechanical stress or shows a higher contractility.
摘要翻译： 本发明涉及通过在将其提交给不同的测试之前或在将其接枝到受体患者之前通过物理或生物化学处理组织来改善人或动物组织的功能的两种新方法。 因此，这样处理的组织具有更大的抵抗机械应力的能力或显示较高的收缩性。
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公开(公告)号：US07614103B2
公开(公告)日：2009-11-10
申请号：US11951840
申请日：2007-12-06
申请人： Benoit Beaudry , Hugo Bastien , Francois Bergeron , Jean-Sébastien Gosselin , Etienne Poulin , Vincent Deschamps-Sonsino , Noemie Seguin-Tremblay
发明人： Benoit Beaudry , Hugo Bastien , Francois Bergeron , Jean-Sébastien Gosselin , Etienne Poulin , Vincent Deschamps-Sonsino , Noemie Seguin-Tremblay
摘要： The present invention provides a stretcher having a brake mechanism that can be selectively activated to influence the movement of the stretcher supported by an inclined surface. The brake mechanism of the stretcher progressively increases the amount of friction between the stretcher and the surface of which the stretcher is supported to reduce or stop movements of the stretcher. The stretcher further includes a pulling member influencing the position or the activation of the brake mechanism on the stretcher and high friction means associated with the bottom side of the stretcher. The present invention also provides a size reduction mechanism requesting limited storage space for the stretcher when not in use and a foot restraint to secure the feet of the patient on the stretcher and offer additional volume to carry additional material with the patient. A method for braking a stretcher on an inclined plane is also disclosed.
摘要翻译： 本发明提供了一种具有制动机构的担架，该制动机构能够被选择性地启动以影响由倾斜表面支撑的担架的移动。 担架的制动机构逐渐增加担架与担架担架的表面之间的摩擦量，以减小或停止担架的移动。 担架还包括影响担架上的制动机构的位置或启动的牵引构件以及与担架的底侧相关联的高摩擦装置。 本发明还提供了一种尺寸减小机构，其在不使用时为担架提供有限的存储空间，并且还提供足部约束以将患者的脚固定在担架上并提供额外的体积以携带患者的附加材料。 还公开了一种用于在倾斜平面上制动担架的方法。
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