公开(公告)号：US06555065B1

公开(公告)日：2003-04-29

申请号：US09554748

申请日：2000-05-18

Applicant: Francois Melet

Inventor： Francois Melet

IPC: G01N3348

CPC classification number: G01N15/1209 ,  Y10T436/101666

Abstract: A compact apparatus for automatically analyzing a blood sample having a pumping assembly, a dilution assembly and a measuring assembly. The pumping assembly includes pumps for air, lysis and diluent. The dilution assembly includes a sampling needle, and containers for waste, white corpuscle dilution, and red corpuscle dilution. The measuring assembly includes a measuring chamber, and a device for counting platelets, red corpuscles, white corpuscles and hemoglobin in the blood sample. Both red and white corpuscles are counted in the same measuring chamber. A plurality of pipes establish fluid communication between the elements of the apparatus. A plurality of electro-valves are adapted to automatically open and close the pipes thereby regulating fluid flow between the pumping assembly, the dilution assembly and the measuring assembly. One of the electro-valves is adapted to shutoff a diluent source and substitute water therefor, whereby the apparatus is rinsed with the water to avoid crystalization.

Abstract translation: 一种用于自动分析具有泵送组件，稀释组件和测量组件的血液样品的紧凑装置。 泵送组件包括用于空气，裂解和稀释剂的泵。 稀释组件包括采样针，废物容器，白细胞稀释和红细胞稀释。 测量组件包括测量室，以及用于在血液样品中计数血小板，红色小体，白色小体和血红蛋白的装置。 红色和白色的小体都被计入同一个测量室。 多个管道在装置的元件之间建立流体连通。 多个电动阀适于自动打开和关闭管道，从而调节泵送组件，稀释组件和测量组件之间的流体流动。 其中一个电动阀适于切断稀释剂源并替代水，由此用水冲洗装置以避免结晶。

公开(公告)号：US5047210A

公开(公告)日：1991-09-10

申请号：US288609

申请日：1988-12-12

Applicant: Francois Melet

Inventor： Francois Melet

IPC: G01N35/04 ,  B01L9/06

CPC classification number: B01L9/06 ,  Y10T436/11

Abstract: A device for presentation of receptacles containing samples of liquid with a view to transferring them to an automatic analyzer. The device comprises a cylindrical drum forming a core integral with at least two circular crowns perforated or with cavities to receive the receptacles and sloping them relative to the axis of the drum which is maintained horizontal during the presentation of the samples with a view to transferring them into the analyzer. Such a device having a small bulk enables ideal agitation as a consequence of the rotation and tipping over of the samples during their presentation.

Abstract translation: 用于呈现包含液体样品的容器的装置，以便将它们转移到自动分析器。 该装置包括一个圆柱形鼓，其形成一个与至少两个穿孔或带有空腔的圆冠形成一体的芯，以容纳容器并相对于滚筒的轴线倾斜它们，以在样品呈现期间保持水平，以便转移它们 进入分析仪。 具有小体积的这种装置使得由于样品在其呈现期间的旋转和翻转而导致理想的搅动。

公开(公告)号：US20070077173A1

公开(公告)日：2007-04-05

申请号：US11541555

申请日：2006-10-03

Applicant: Francois Melet

Inventor： Francois Melet

IPC: G01N35/00

CPC classification number: G01N21/253 ,  G01N21/274 ,  G01N21/31 ,  G01N35/00069 ,  G01N35/025 ,  G01N2021/3133 ,  G01N2021/3166 ,  G01N2021/3177 ,  G01N2201/0415 ,  G01N2201/06186 ,  G01N2201/12792 ,  G01N2201/1285

Abstract: A compact analyzer for dry biochemical analysis of blood samples, integrating onto a common chassis (11): a measuring chamber (20) adapted to receive a disposable rotor (13) including microtanks (13A, 13B) containing dry reagents, a digital dilution module (21) of fixed or variable ratio defined as a function of the species of the sample to be analyzed, a sample centrifuging module (12) adapted, inside the measuring chamber, to centrifuge the rotor and position it angularly, an optical module adapted to apply beams of light to microtanks of the rotor, this optical module including a flash-lamp type light source (14) and a reference light sensor (16), an electronic processing and control system (23, 24, 25) including an external memory reader (26) adapted to read a portable external memory (27) containing at least information characteristic of at least the disposable rotor in use.

Abstract translation: 一种用于血液样品的干生物化学分析的紧凑型分析仪，集成到公共底盘（11）上：测量室（20），其适于容纳包含含有干试剂的微量池（13A，13B）的一次性转子（13），数字 固定或可变比率的稀释模块（21），其定义为待分析样品的种类的函数;样品离心模块（12），其适于在所述测量室内部离心转子并将其定位，光学模块 该光学模块包括闪光灯型光源（14）和参考光传感器（16），电子处理和控制系统（23,24,25）包括： 外部存储器读取器（26）适于读取至少包含使用中的一次性转子的信息特征的便携式外部存储器（27）。

公开(公告)号：US5054498A

公开(公告)日：1991-10-08

申请号：US399544

申请日：1989-08-16

Applicant: Francois Melet

Inventor： Francois Melet

IPC: A61B5/15

CPC classification number: A61B5/153 ,  A61B5/15003 ,  A61B5/150213 ,  A61B5/150236 ,  A61B5/150351 ,  A61B5/150389 ,  A61B5/150503

Abstract: A device for taking samples of arterial blood with a view to its subsequent gasometric analysis comprises a main body forming a reservoir in which a free piston travels. Said piston isolates the blood from the air and cannot be manipulated by the operator. The device also includes a filter located at the end of the piston stroke which is permeable to air and impermeable to blood, allows the operator to observe the blood as it advances, and acts as a barrier to excessive blood flow, and a stopper which ulitmately seals the system and facilitates its tranport. In contrast to conventional invasive systems, this device, which does not need to be sterilized, makes it possible to obtain a blood sample which, after sampling, is only minimally contaminated with the ambient air, is available in a sufficient quantity, and is only slightly coagulable.

Abstract translation: PCT No.PCT / FR88 / 00622 Sec。 371日期1989年8月16日 102（e）日期1989年8月16日PCT提交1988年12月16日PCT公布。 出版物WO89 / 05607 日期：1989年6月29日。用于采集动脉血样本的装置，以便随后进行气体分析，包括形成自由活塞行进的储存器的主体。 所述活塞将血液与空气隔离，不能由操作者操纵。 该装置还包括位于活塞行程末端的过滤器，该过滤器可渗透空气并且不透血，允许操作者在血液流动时观察血液，并且作为过量血液流动的障碍物，以及一种阻塞剂 密封系统并促进其运输。 与传统的侵入性系统相比，这种不需要消毒的装置使得可以获得在采样之后仅被环境空气最低限度地污染的血液样品，其可用量足够，只有 轻微凝固。