公开(公告)号：US10376147B2

公开(公告)日：2019-08-13

申请号：US14097323

申请日：2013-12-05

申请人： Fred Wood ,  Dmitry Yavid ,  Joe Zott ,  Ron Goldman

发明人： Fred Wood ,  Dmitry Yavid ,  Joe Zott ,  Ron Goldman

IPC分类号： A61B5/00 ,  A61B18/20 ,  A61B18/00

摘要： A fluorescence imaging device detects fluorescence in parts of the visible and invisible spectrum, and projects the fluorescence image directly on the human body, as well as on a monitor, with improved sensitivity, video frame rate and depth of focus, and enhanced capabilities of detecting distribution and properties of multiple fluorophores. Direct projection of three-dimensional visible representations of florescence on three-dimensional body areas advantageously permits view of it during surgical procedures, including during cancer removal, reconstructive surgery and wound care, etc. A NIR laser and a human visible laser (HVL) are aligned coaxially and scanned over the operating field of view. When the NIR laser passes over the area where the florescent dye is present, it energizes the dye which emits at a shifted NIR frequency detected by a photo diode. The HVL is turned on when emission is detected, providing visual indication of those positions.

公开(公告)号：US10517483B2

公开(公告)日：2019-12-31

申请号：US14097313

申请日：2013-12-05

申请人： Fred Wood ,  Dmitry Yavid ,  Joe Zott ,  Ron Goldman

发明人： Fred Wood ,  Dmitry Yavid ,  Joe Zott ,  Ron Goldman

IPC分类号： A61B5/00 ,  A61B18/20 ,  A61B18/00

摘要： A fluorescence imaging device detects fluorescence in parts of the visible and invisible spectrum, and projects the fluorescence image directly on the human body, as well as on a monitor, with improved sensitivity, video frame rate and depth of focus, and enhanced capabilities of detecting distribution and properties of multiple fluorophores. Direct projection of three-dimensional visible representations of florescence on three-dimensional body areas advantageously permits viewing of it during surgical procedures, including during cancer removal, reconstructive surgery and wound care, etc. A NIR laser and a human visible laser (HVL) are aligned coaxially and scanned over the operating field of view. When the NIR laser passes over the area where the florescent dye is present, it energizes the dye which emits at a shifted NIR frequency detected by a photo diode. The HVL is turned on when emission is detected, providing visual indication of those positions.

公开(公告)号：US20140187967A1

公开(公告)日：2014-07-03

申请号：US14097323

申请日：2013-12-05

申请人： Fred Wood ,  Dmitry Yavid ,  Joe Zott ,  Ron Goldman

发明人： Fred Wood ,  Dmitry Yavid ,  Joe Zott ,  Ron Goldman

IPC分类号： A61B18/20 ,  A61B5/00

CPC分类号： A61B5/0071 ,  A61B5/0077 ,  A61B5/742 ,  A61B18/20 ,  A61B2018/00577

摘要： A fluorescence imaging device detects fluorescence in parts of the visible and invisible spectrum, and projects the fluorescence image directly on the human body, as well as on a monitor, with improved sensitivity, video frame rate and depth of focus, and enhanced capabilities of detecting distribution and properties of multiple fluorophores. Direct projection of three-dimensional visible representations of florescence on three-dimensional body areas advantageously permits view of it during surgical procedures, including during cancer removal, reconstructive surgery and wound care, etc. A NIR laser and a human visible laser (HVL) are aligned coaxially and scanned over the operating field of view. When the NIR laser passes over the area where the florescent dye is present, it energizes the dye which emits at a shifted NIR frequency detected by a photo diode. The HVL is turned on when emission is detected, providing visual indication of those positions.

摘要翻译： 荧光成像装置在可见光和不可见光谱的一部分中检测荧光，并将荧光图像直接投射在人体以及显示器上，具有改进的灵敏度，视频帧率和焦深，以及增强的检测能力 分布和多种荧光团的性质。 荧光三维可视表示直接投影在三维身体区域有利于允许在手术过程中观察它，包括在癌症消除，重建手术和伤口护理等期间。近红外激光和人类可见激光（HVL）是 同轴对齐并在操作视野上进行扫描。 当NIR激光通过存在荧光染料的区域时，它激发以由光电二极管检测到的移位的NIR频率发射的染料。 当检测到发射时，HVL被接通，提供这些位置的视觉指示。

公开(公告)号：US20140187931A1

公开(公告)日：2014-07-03

申请号：US14097313

申请日：2013-12-05

申请人： Fred Wood ,  Dmitry Yavid ,  Joe Zott ,  Ron Goldman

发明人： Fred Wood ,  Dmitry Yavid ,  Joe Zott ,  Ron Goldman

IPC分类号： A61B5/00

摘要： A fluorescence imaging device detects fluorescence in parts of the visible and invisible spectrum, and projects the fluorescence image directly on the human body, as well as on a monitor, with improved sensitivity, video frame rate and depth of focus, and enhanced capabilities of detecting distribution and properties of multiple fluorophores. Direct projection of three-dimensional visible representations of florescence on three-dimensional body areas advantageously permits view of it during surgical procedures, including during cancer removal, reconstructive surgery and wound care, etc. A NIR laser and a human visible laser (HVL) are aligned coaxially and scanned over the operating field of view. When the NIR laser passes over the area where the florescent dye is present, it energizes the dye which emits at a shifted NIR frequency detected by a photo diode. The HVL is turned on when emission is detected, providing visual indication of those positions.

摘要翻译： 荧光成像装置在可见光和不可见光谱的一部分中检测荧光，并将荧光图像直接投射在人体以及显示器上，具有改进的灵敏度，视频帧率和焦深，以及增强的检测能力 分布和多种荧光团的性质。 荧光三维可视表示直接投影在三维身体区域有利于允许在手术过程中观察它，包括在癌症消除，重建手术和伤口护理等期间。近红外激光和人类可见激光（HVL）是 同轴对齐并在操作视野上进行扫描。 当NIR激光通过存在荧光染料的区域时，它激发以由光电二极管检测到的移位的NIR频率发射的染料。 当检测到发射时，HVL被接通，提供这些位置的视觉指示。

公开(公告)号：US10376148B2

公开(公告)日：2019-08-13

申请号：US14097337

申请日：2013-12-05

申请人： Fred Wood ,  Dmitry Yavid ,  Joe Zott ,  Ron Goldman

发明人： Fred Wood ,  Dmitry Yavid ,  Joe Zott ,  Ron Goldman

IPC分类号： A61B5/00 ,  A61B18/20 ,  A61B18/00

摘要： A fluorescence imaging device detects fluorescence in parts of the visible and invisible spectrum, and projects the fluorescence image directly on the human body, as well as on a monitor, with improved sensitivity, video frame rate and depth of focus, and enhanced capabilities of detecting distribution and properties of multiple fluorophores. Direct projection of three-dimensional visible representations of florescence on three-dimensional body areas advantageously permits view of it during surgical procedures, including during cancer removal, reconstructive surgery and wound care, etc. A NIR laser and a human visible laser (HVL) are aligned coaxially and scanned over the operating field of view. When the NIR laser passes over the area where the florescent dye is present, it energizes the dye which emits at a shifted NIR frequency detected by a photo diode. The HVL is turned on when emission is detected, providing visual indication of those positions.

公开(公告)号：US20140187879A1

公开(公告)日：2014-07-03

申请号：US14097337

申请日：2013-12-05

申请人： Fred Wood ,  Dmitry Yavid ,  Joe Zott ,  Ron Goldman

发明人： Fred Wood ,  Dmitry Yavid ,  Joe Zott ,  Ron Goldman

IPC分类号： A61B5/00 ,  A61B18/20

CPC分类号： A61B5/0071 ,  A61B5/0077 ,  A61B5/742 ,  A61B18/20 ,  A61B2018/00577

摘要： A fluorescence imaging device detects fluorescence in parts of the visible and invisible spectrum, and projects the fluorescence image directly on the human body, as well as on a monitor, with improved sensitivity, video frame rate and depth of focus, and enhanced capabilities of detecting distribution and properties of multiple fluorophores. Direct projection of three-dimensional visible representations of florescence on three-dimensional body areas advantageously permits view of it during surgical procedures, including during cancer removal, reconstructive surgery and wound care, etc. A NIR laser and a human visible laser (HVL) are aligned coaxially and scanned over the operating field of view. When the NIR laser passes over the area where the florescent dye is present, it energizes the dye which emits at a shifted NIR frequency detected by a photo diode. The HVL is turned on when emission is detected, providing visual indication of those positions.

摘要翻译： 荧光成像装置在可见光和不可见光谱的一部分中检测荧光，并将荧光图像直接投射在人体以及显示器上，具有改进的灵敏度，视频帧率和焦深，以及增强的检测能力 分布和多种荧光团的性质。 荧光三维可视表示直接投影在三维身体区域有利于允许在手术过程中观察它，包括在癌症消除，重建手术和伤口护理等期间。近红外激光和人类可见激光（HVL）是 同轴对齐并在操作视野上进行扫描。 当NIR激光通过存在荧光染料的区域时，它激发以由光电二极管检测到的移位的NIR频率发射的染料。 当检测到发射时，HVL被接通，提供这些位置的视觉指示。

公开(公告)号：US20150157257A1

公开(公告)日：2015-06-11

申请号：US14101580

申请日：2013-12-10

申请人： Vincent Luciano ,  Ron Goldman ,  Fred Wood

发明人： Vincent Luciano ,  Ron Goldman ,  Fred Wood

IPC分类号： A61B5/00 ,  A61B1/07

CPC分类号： A61B5/489 ,  A61B1/00172 ,  A61B1/063 ,  A61B1/0676 ,  A61B1/07 ,  A61B5/0062 ,  A61B5/0064 ,  A61B5/0084 ,  A61B5/062 ,  A61B5/6831

摘要： A vein-illumination device includes: a base, a frame connected thereto using a flexible hinge, allowing the frame to move angularly, with respect to the base, in a first direction, a means for exciting angular oscillations of the frame, an elastic torsional element having a proximal end attached to the frame and a distal end attached to a mirror, and a means for exciting the angular oscillations of the mirror. The torsional element allows the mirror to move angularly with respect to the frame in a second direction, generally perpendicular to the first direction. The invention also includes a device for optically inspecting confined spaces, which includes at least one laser light source, a scanning means that scans one or more laser beams in a two-dimensional pattern over an inspection area, and at least one light detector, sensitive to the light of the laser beam(s) being reflected from the inspection area.

摘要翻译： 静脉照明装置包括：基座，使用柔性铰链连接到其上的框架，允许框架在第一方向上相对于基座成角度地移动，用于激励框架的角振荡的装置，弹性扭转 元件具有附接到框架的近端和附接到反射镜的远端，以及用于激励反射镜的角振荡的装置。 扭转元件允许反射镜在大致垂直于第一方向的第二方向上相对于框架成角度地移动。 本发明还包括用于光学检查限制空间的装置，其包括至少一个激光光源，在检查区域上以二维图案扫描一个或多个激光束的扫描装置，以及至少一个敏感的光检测器 对于从检查区域反射的激光束的光。

公开(公告)号：US20130123640A1

公开(公告)日：2013-05-16

申请号：US13649234

申请日：2012-10-11

申请人： Ron Goldman ,  Stephen P. Conlon ,  Vincent Luciano ,  Fred Wood

发明人： Ron Goldman ,  Stephen P. Conlon ,  Vincent Luciano ,  Fred Wood

IPC分类号： A61B5/00

CPC分类号： A61B5/489 ,  A61B5/004 ,  A61B5/0059 ,  A61B5/0062 ,  A61B5/0064 ,  A61B5/0079 ,  A61B5/0082 ,  A61B5/4887 ,  A61B5/7221 ,  A61B5/748 ,  A61B2560/0431 ,  A61B2562/0233 ,  A61B2562/028 ,  A61M5/427

摘要： The present invention is a Miniature Vein Enhancer that includes a Miniature Projection Head, The Miniature Projection Head may be operated in one of three modes, AFM, DBM, and RTM. The Miniature Projection Head of the present invention projects an image of the veins of a patient, which aids the practitioner in pinpointing a vein for an intravenous drip, blood test, and the like. The Miniature projection head may have a cavity for a power source or it may have a power source located in a body portion of the Miniature Vein Enhancer. The Miniature Vein Enhancer may be attached to one of several improved needle protectors, or the Miniature Vein Enhancer may be attached to a body similar to a flashlight for hand held use. The Miniature Vein Enhancer of the present invention may also be attached to a magnifying glass, a flat panel display, and the like.

摘要翻译： 本发明是一种微型静脉增强器，其包括微型投影头，微型投影头可以以AFM，DBM和RTM三种模式之一操作。 本发明的微型投影头投影患者的静脉的图像，其帮助从业者精确定位静脉用于静脉滴注，血液检查等。 微型投影头可以具有用于电源的空腔，或者其可以具有位于微型静脉增强器的主体部分中的电源。 微型静脉增强器可以附接到几个改进的针保护器中的一个，或者微型静脉增强器可以附接到类似于手电筒的用于手持使用的身体。 本发明的微型静脉增强器还可以附接到放大镜，平板显示器等。

公开(公告)号：US08244333B2

公开(公告)日：2012-08-14

申请号：US11807057

申请日：2007-05-25

申请人： Fred Wood ,  Ron Goldman ,  Stephen Conlon ,  Vincent Luciano

发明人： Fred Wood ,  Ron Goldman ,  Stephen Conlon ,  Vincent Luciano

IPC分类号： A61B6/00

CPC分类号： A61B5/0059 ,  A61B5/0062 ,  A61B5/489

摘要： The present invention is a Miniature Vein Enhancer that includes a Miniature Projection Head. The Miniature Projection Head may be operated in one of three modes, AFM, DBM, and RTM. The Miniature Projection Head of the present invention projects an image of the veins of a patient, which aids the practitioner in pinpointing a vein for an intravenous drip, blood test, and the like. The Miniature projection head may have a cavity for a power source or it may have a power source located in a body portion of the Miniature Vein Enhancer. The Miniature Vein Enhancer may be attached to one of several improved needle protectors, or the Miniature Vein Enhancer may be attached to a body similar to a flashlight for hand held use. The Miniature Vein Enhancer of the present invention may also be attached to a magnifying glass, a flat panel display, and the like.

摘要翻译： 本发明是一种微型静脉增强器，其包括微型投影头。 微型投影头可以以AFM，DBM和RTM三种模式之一操作。 本发明的微型投影头投影患者的静脉的图像，其帮助从业者精确定位静脉用于静脉滴注，血液检查等。 微型投影头可以具有用于电源的空腔，或者其可以具有位于微型静脉增强器的主体部分中的电源。 微型静脉增强器可以附接到几个改进的针保护器中的一个，或者微型静脉增强器可以附接到类似于手电筒的用于手持使用的身体。 本发明的微型静脉增强器还可以附接到放大镜，平板显示器等。

公开(公告)号：US20080287806A1

公开(公告)日：2008-11-20

申请号：US11807064

申请日：2007-05-25

申请人： Fred Wood ,  Ron Goldman ,  Stephen Conlon ,  Vincent Luciano

发明人： Fred Wood ,  Ron Goldman ,  Stephen Conlon ,  Vincent Luciano

IPC分类号： A61B6/00

CPC分类号： A61B5/489 ,  A61B5/004 ,  A61B5/0059 ,  A61B5/0062 ,  A61B5/0064 ,  A61B5/0079 ,  A61B5/0082 ,  A61B5/4887 ,  A61B5/7221 ,  A61B5/748 ,  A61B2560/0431 ,  A61B2562/0233 ,  A61B2562/028 ,  A61M5/427

摘要： The present invention is a Miniature Vein Enhancer that includes a Miniature Projection Head. The Miniature Projection Head may be operated in one of three modes, AFM, DBM, and RTM. The Miniature Projection Head of the present invention projects an image of the veins of a patient, which aids the practitioner in pinpointing a vein for an intravenous drip, blood test, and the like. The Miniature projection head may have a cavity for a power source or it may have a power source located in a body portion of the Miniature Vein Enhancer. The Miniature Vein Enhancer may be attached to one of several improved needle protectors, or the Miniature Vein Enhancer may be attached to a body similar to a flashlight for hand held use. The Miniature Vein Enhancer of the present invention may also be attached to a magnifying glass, a flat panel display, and the like.

摘要翻译： 本发明是一种微型静脉增强器，其包括微型投影头。 微型投影头可以以AFM，DBM和RTM三种模式之一操作。 本发明的微型投影头投影患者的静脉的图像，其帮助从业者精确定位静脉用于静脉滴注，血液检查等。 微型投影头可以具有用于电源的空腔，或者其可以具有位于微型静脉增强器的主体部分中的电源。 微型静脉增强器可以附接到几个改进的针保护器中的一个，或者微型静脉增强器可以附接到类似于手电筒的用于手持使用的身体。 本发明的微型静脉增强器还可以附接到放大镜，平板显示器等。